Dimerization of the extracellular domain of the human growth hormone receptor by …
Mark Ultsch
Science
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Activation of Growth Hormone Receptors by Growth Hormone and Growth Hormone Antagonist Dimers: Insights into Receptor Triggering
Wendy Chen
Molecular Endocrinology, 2008
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Structural basis for activation of the growth hormone-releasing hormone receptor
Qingtong Zhou
Nature Communications, 2020
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Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
Mark Ultsch
Science, 1991
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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
Mark Ultsch
Journal of Molecular Biology, 1998
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Order and disorder – an integrative structure of the full-length human growth hormone receptor
Maikel Rheinstädter
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A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling
Louise Metherell
Journal of Endocrinology, 2006
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Intra-molecular Conformational Stability in Human Growth Hormone
rajendra Koirala
Journal of Nepal Physical Society, 2020
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Growth Hormone (GH)-independent Dimerization of GH Receptor by a Leucine Zipper Results in Constitutive Activation
Nils Billestrup
Journal of Biological Chemistry, 2000
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Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor
Anatoly Urban
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018
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Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors
Mark Ultsch
Protein Science, 1994
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Molecular Dissection of the Growth Hormone Receptor
Jens Amstrup
Annals of The New York Academy of Sciences, 1995
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Rational Design of Potent Antagonists to the Human Growth Hormone Receptor
David Goeddel
Science, 1992
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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization
Miao Sun
Proceedings of the National Academy of Sciences, 2003
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Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface
Gennady Verkhivker
Proteins: Structure, Function, and Genetics, 2003
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Evidence for Involvement of the Carboxy Terminus of Helix 1 of Growth Hormone in Receptor Binding: Use of Charge Reversal Mutagenesis to Account for Calcium Dependence of Binding and for Design of Higher Affinity Analogs
Ross Barnard
Biochemistry, 1994
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Evidence for Involvement of the Carboxy Terminus of Helix 1 of Growth Hormone In Receptor Binding: Use of Charge Reversal Mutagenesis to Account for Calcium …
Michael Waters, Ross Barnard
Biochemistry, 1994
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The Molecular Properties of Human Growth Hormone
Salvatore Aloj
Journal of Biological Chemistry, 1972
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Signal transduction of the growthhormone (GH) receptor, and GH-binding protein
Jerome Wojcik
Growth Hormone & IGF Research, 1999
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Conformational analysis of cyclo (2, 9)‐Ac‐QCRSVEGSCG‐OH from the C‐terminal loop of human growth hormone
Soma Chakrabarti
The Journal of …, 1997
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Naturally-occurring missense mutations in the human growth hormone-releasing hormone receptor alter ligand binding
Roberto Salvatori
Journal of Endocrinology, 2005
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Conformational analysis of human growth hormone [6-13] peptide analogues
Milton Hearn
International Journal of Peptide and Protein Research, 1996
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Distinct Cytoplasmic Domains of the Growth Hormone Receptor Are Required for Glucocorticoid- and Phorbol Ester-induced Decreases in Growth Hormone (GH) Binding
Nils Billestrup
Journal of Biological Chemistry, 1996
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Defects in growth hormone receptor signaling
Alicia Belgorosky, JM Wit
Trends in Endocrinology & Metabolism, 2007
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Alternatively spliced forms in the cytoplasmic domain of the human growth hormone (GH) receptor regulate its ability to generate a soluble GH-binding protein
Marie-laure Sobrier
Proceedings of the National Academy of Sciences, 1996
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Activation of Chimeric and Full-length Growth Hormone Receptors by Growth Hormone Receptor Monoclonal Antibodies
Zida Wu
Journal of Biological Chemistry, 1998
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The D152H mutation found in growth hormone insensitivity syndrome impairs expression and function of human growth hormone receptor but is silent in rat receptor
Jerome Wojcik
Journal of Molecular Endocrinology, 1998
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A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization
Michael A Preece
The EMBO journal, 1994
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Interaction profiling of growth hormone receptor and growth hormone proteins in Labeo rohita: an insight using molecular modelling and docking approaches
Iliyas Rashid
2019
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A ligand-receptor fusion of growth hormone forms a dimer and is a potent long-acting agonist
Christian Strasburger
Nature Medicine, 2007
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