Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule (original) (raw)

Conformational changes required in the human growth hormone receptor for growth hormone signaling

Isabel Mérida

Journal of Biological …, 1997

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A Role for a Helical Connector between Two Receptor Binding Sites of a Long-chain Peptide Hormone

Sven Rothemund

Journal of Biological Chemistry, 2000

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Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat

L Van der Ploeg

Endocrinology, 1997

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Inhibition of signal transduction by a splice variant of the growth hormone—releasing hormone receptor expressed in human pituitary adenomas

Soji Kasayama

Metabolism, 1998

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Growth hormone activity in mitochondria depends on GH receptor Box 1 and involves caveolar pathway targeting

dominique ardail

Experimental Cell Research, 2005

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Adult growth hormone deficiency

John Monson

Clinical Medicine, 2003

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Hypothalamic and Hypophyseal Regulation of Growth Hormone Secretion

Constance Hammond

Cellular and Molecular Neurobiology, 1998

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Single step recombinant human growth hormone (rhGH) purification from milk by peptide affinity chromatography

Silvia Camperi

Biotechnology Progress, 2018

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The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

Kirsten Berk

Endocrinology and Metabolism, 2024

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Structural basis for activation of the growth hormone-releasing hormone receptor

Qingtong Zhou

Nature Communications, 2020

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A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling

Louise Metherell

Journal of Endocrinology, 2006

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The activation mechanism of glycoprotein hormone receptors with implications in the cause and therapy of endocrine diseases

Sven Rothemund

Experimental and Clinical Endocrinology & Diabetes, 2015

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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization

Miao Sun

Proceedings of the National Academy of Sciences, 2003

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Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin: Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a

L Van der Ploeg

Journal of Medicinal Chemistry, 2000

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Hypoglycaemic activity of an analogue of human growth hormone [6-13] incorporating a d-ala-pro dipeptide unit

Milton Hearn

Bioorganic & Medicinal Chemistry Letters, 1993

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Order and disorder – an integrative structure of the full-length human growth hormone receptor

Maikel Rheinstädter

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Principles of Endocrinology and Hormone Action

Paco G. López

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Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor

Anatoly Urban

Biochimica et Biophysica Acta (BBA) - General Subjects, 2018

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Binding domain characterization of growth hormone secretagogue receptor

Roy Smith

Journal of Translational Internal Medicine

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The Antibodies against the Computationally Designed Mimic of the Glycoprotein Hormone Receptor Transmembrane Domain Provide Insights into Receptor Activation and Suppress the Constitutively Activated Receptor Mutants

Rajan Dighe

Journal of Biological Chemistry, 2012

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Position stand on androgen and human growth hormone use

Darryn Willoughby

2009

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Specific monoclonal antibodies and ultrasensitive immunoassays for 20K and 22K human growth hormone

Emral Devany

Growth Hormone & IGF Research, 2010

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Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells

Jens Nielsen

Proceedings of the National Academy of Sciences, 1990

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Extreme Position Dependence of a Canonical Hormone Response Element

Steven Nordeen

Molecular Endocrinology, 1998

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Microbial expression of a gene for human growth hormone

David Goeddel

1982

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