Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method (original) (raw)
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Coronary artery calcium volume scores on electron beam tomography in 12,936 asymptomatic adults
The American Journal of Cardiology, 2004
We developed age-and gender-specific normative tables of calcium volume scores by using data from 12,936 asymptomatic patients who underwent electron beam tomographic scanning and compared the volume with the Agatston scores obtained in the same subjects. The 2 scores increased as the number of atherosclerotic risk factors increased. The volume scores were statistically smaller than the Agatston scores at the upper quartile level.
American Journal of Cardiology, 2000
Electron beam computed tomography is widely used to screen for coronary artery calcium (CAC). We evaluated the relation of CAC to future cardiovascular disease events in 926 asymptomatic persons (735 men and 191 women, mean age 54 years) who underwent a baseline electron beam computed tomographic scan. All subjects included in this report returned a follow-up questionnaire 2 to 4 years (mean 3.3) after scanning, inquiring about myocardial infarction, stroke, and revascularizations. Sixty percent of men and 40% of women had a positive scan at baseline. Twenty-eight cardiovascular events occurred and were confirmed by blinded medical record review. The presence of CAC (a total calcium score of >0) and increasing score quartiles were related to the occurrence of new myocardial infarction (p <0.05), revascularizations (p <0.001), and total cardiovascular events (p <0.001). Those with scores at or above the median (score of 5) had a relative risk of 4.5 (p <0.01) for new events. From Cox regression models, adjusted for age, gender, and coronary risk factors, the relative risks for those with scores of 81 to 270 and >271 (compared with 0) for cardiovascular events were 4.5 (p <0.05) and 8.8 (p <0.001), respectively. These data support previous reports showing CAC to be a modest predictor of future cardiovascular events.
The American Journal of Cardiology, 2004
This angiographically correlated study reports on, for the first time, age-and gender-based distribution of the volumetric calcium score in a large group of patients with suspected coronary artery disease. Volumetric calcium data predicted significant coronary artery disease (>50% lumen diameter stenosis) as well as the traditional Agatston score. Exclusion of any calcium was highly accurate in ruling out obstructive disease in symptomatic subjects >50 years of age. ᮊ2004 by Excerpta Medica, Inc.
Coronary Artery Calcium Score: A Review
Iranian Red Crescent Medical Journal, 2013
Context: Coronary artery disease (CAD) is the foremost cause of death in many countries and hence, its early diagnosis is usually concerned as a major healthcare priority. Coronary artery calcium scoring (CACS) using either electron beam computed tomography (EBCT) or multislice computed tomography (MSCT) has been applied for more than 20 years to provide an early CAD diagnosis in clinical routine practice. Moreover, its association with other body organs has been a matter of vast research. Evidence Acquisition: In this review article, techniques of CACS using EBCT and MSCT scanners as well as clinical and research indications of CACS are searched from PubMed, ISI Web of Science, Google Scholar and Scopus databases in a time period between late 1970s through July 2013 and following appropriate selection, dealt with. Moreover, the previous and ongoing research subjects and their results are discussed. Results: The CACS is vastly applied in early detection of CAD and in many other research fields. Conclusions: CACS has remarkably changed the screening techniques to detect CAD earlier than before and is generally accepted as a standard of reference for determination of risk of further cardiac events.
Non-invasive evaluation of coronary calcium
La radiologia medica
With the increasing diffusion of 4-row,16-row and 64-row multislice computed tomography scanners, widespread coronary calcium scoring has become possible in Europe. This relatively easy-to-perform test has a high sensitivity and low specificity for the detection of significant coronary artery stenosis, and may have an important role in the risk stratification for future coronary artery events in selected groups of patients, such as those immediately at risk. This study reviews the techniques available for coronary calcium scoring (electron beam tomography and multislice computed tomography) with their respective protocols, as well as their advantages and disadvantages. The methods for interpreting the results, the potential indications and the clinical applications of the techniques are also described.
Predictors of aortic and coronary artery calcium on a screening electron beam tomographic scan
The American Journal of Cardiology, 2003
E lectron beam tomography offers an opportunity to noninvasively identify atherosclerotic disease via visualization of calcified plaques and facilitates the study of the relation between various risk factors and the development of atherosclerosis. Additionally, the utility of coronary calcium as a risk stratification tool is receiving marked attention. In the present study, we performed electron beam tomographic (EBT) scans of the coronary arteries and the entire aorta in 245 subjects who were asymptomatic for coronary artery disease. We intended to analyze the contribution of several risk factors to the development of medium-and large-size vessel atherosclerosis and study the relation of disease in these 2 territories.