Microglial Activation Milieu Controls Regulatory T Cell Responses (original) (raw)

Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

Luciano Adorini

Immunology Today, 2000

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Comparison of microglia and infiltrating CD11c+ cells as antigen presenting cells for T cell proliferation and cytokine response

Trevor Owens

Journal of Neuroinflammation, 2014

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Microglia and central nervous system immunity

Isaac Yang

Neurosurgery clinics of North America, 2010

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Mechanisms of IL-10 Production in Human Microglia-T Cell Interaction

Garnette Sutherland

The Journal of Immunology

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Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation

Luciano Adorini

Journal of immunology (Baltimore, Md. : 1950), 1998

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Adoptive transfer of cytokine-induced immunomodulatory adult microglia attenuates experimental autoimmune encephalomyelitis in DBA/1 mice

Muhammad Sohel Mia

Glia, 2014

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CD40-CD154 interaction and IFN-γ are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells

Luciano Adorini

The Journal of Immunology

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Microglia and the control of autoreactive T cell responses

Monica Carson

Neurochemistry International, 2006

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Microglia: gatekeepers of central nervous system immunology

Peter Ponsaerts

Journal of Leukocyte Biology, 2008

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The role of microglia in central nervous system immunity and glioma immunology

Isaac Yang

Journal of Clinical Neuroscience, 2010

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Early activation of microglia as antigen-presenting cells correlates with T cell-mediated protection and repair of the injured central nervous system

Ziv Porat

Journal of Neuroimmunology, 2004

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Regulation of innate immune responses in the brain

Serge Rivest

Nature reviews. Immunology, 2009

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Microglia Responses to Pro-inflammatory Stimuli (LPS, IFNγ+TNFα) and Reprogramming by Resolving Cytokines (IL-4, IL-10

Starlee Lively Odorico

2018

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Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases

Jingchun Chen

Frontiers in Cellular Neuroscience, 2021

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Midbrain microglia mediate a specific immunosuppressive response under inflammatory conditions

AMAIA VILAS

Journal of Neuroinflammation, 2019

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In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed

Nieske Brouwer

Glia, 2014

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Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS

Knut Biber

Glia, 2008

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Astrocyte‐targeted IL‐10 production decreases proliferation and induces a downregulation of activated microglia/macrophages after PPT

Beatriz Almolda

Glia, 2018

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Neonatal and adult microglia cross-present exogenous antigens

Dominique Couez

Glia, 2008

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CD4 T Cells Induce A Subset of MHCII-Expressing Microglia that Attenuates Alzheimer Pathology

Daniella Apelblat

iScience, 2019

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Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

Wenda Gao

Nature Medicine, 2007

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Microglia and Microglia-Like Cell Differentiated from DC Inhibit CD4 T Cell Proliferation

Sudha Agarwal

PLoS ONE, 2009

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The role of the immune system in driving neuroinflammation

Marina Lynch

Brain and Neuroscience Advances

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Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 cells

Sandra Columba-cabezas

2000

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Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAE

Beatriz Almolda

Journal of Neuroimmunology, 2010

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The microglial "activation" continuum: from innate to adaptive responses

Jun Tan

Journal of Neuroinflammation, 2005

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Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation

Vijay Kuchroo

Clinical Immunology, 2007

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Systemic sterile induced-co-expression of IL-12 and IL-18 drives IFN-γ-dependent activation of microglia and recruitment of MHC-II-expressing inflammatory monocytes into the brain

Pablo Iribarren

bioRxiv (Cold Spring Harbor Laboratory), 2020

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Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10

Beatriz Almolda

Brain, Behavior, and Immunity, 2015

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