The Complex Interplay Between Extracellular Matrix and Cells in Tissues (original) (raw)
2019, Methods in Molecular Biology
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Principles of Medical Biochemistry, 2012
The exTracellular MaTrix chapter 14 The cells of soft tissues such as liver, brain, and epithelia are separated only by narrow clefts about 20nm wide. The mechanical properties of these tissues are determined by the cytoskeleton and by specialized cell-cell adhesions. Connective tissues, in contrast, consist mainly of extracellular matrix. The mechanical properties of these tissues are determined by the composition of the extracellular matrix. Several building materials contribute to the extracellular matrix (Fig. 14.1): * Bone from which the inorganic components (mainly calcium phosphates) have been removed by acid treatment. † Mainly in the dermis. The major structural proteins of the epidermis are the keratins (see Chapter 13). p0010 p0015 o0010 o0015 o0020 o0025 s0010 p0040 p0045 p0050 f0090 t0010 To protect the rights of the author(s) and publisher we inform you that this PDF is an uncorrected proof for internal business use only by the author(s), editor(s), reviewer(s), Elsevier and typesetter SPi. It is not allowed to publish this proof online or in print. This proof copy is the copyright property of the publisher and is confidential until formal publication. These proofs may contain colour figures. Those figures may print black and white in the final printed book if a colour print product has not been planned. The colour figures will appear in colour in all electronic versions of this book.
The cells of soft tissues such as liver, brain, and epithelia are separated only by narrow clefts about 20 nm wide. The mechanical properties of these tissues are determined by the cytoskeleton and by specialized cell-cell adhesions.
Biochemistry and Molecular Biology Education, 2010
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