A Possible Role of Medicinal Plants in finding a Cure for Covid-19 (original) (raw)
Related papers
Potential medicinal plant remedies and their possible mechanisms against COVID-19: A review
Ife Journal of Science, 2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak was first reported in Wuhan, a city in Hubei Province of China in December, 2019 and is known to be responsible for the novel coronavirus disease (COVID-19). COVID-19 was declared a pandemic in March, 2020 and since then, it has caused a number of deaths in over 200 countries around the world. Extensive researches have continued in the search of effective vaccines or drug compounds against SARS-CoV-2 and a total of 64 vaccines are currently in clinical trials with 12 currently approved for use by different regulatory bodies, depending on the country. Since the outbreak of SARS-CoV-2, many countries have utilised traditional herbal medicines alongside conventional drugs for the treatment of infected patients. In this review, traditional medicines used to prevent or treat SARS-CoV-2 infection are listed along with the plant parts as used by the traditional healers. Additionally, the possible mechanisms responsible f...
The Perspectives of Medicinal Plants for COVID-19 Treatment: A Review
2020
The World Health Organization (WHO) declared the COVID-19 as a pandemic disease due to its rapid spreading worldwide, caused by a novel coronavirus (SARS-CoV-2) that has brought about many fatalities. Until now, no effective treatment in the form of anti-virus medication or vaccine has been available for the disease. Therefore, this review aimed to identify some important medicinal plants with herbal formulae and guidelines which are used to treat viral diseases especially pandemic COVID-19 disease. Based on this argument, an online search was performed, which assisted to identify a group of plant species harboring antiviral properties. In the recent past, some natural herbal compounds prepared from existing medicinal plants available surrounding us have demonstrated encouraging antiviral properties. This review can be used as guidance of traditional medicine for the alternative treatment of COVID-19 disease with the utilization of medicinal plants.
Insights in Biology and Medicine, 2021
The outbreak of new coronavirus acute respiratory disease (SARS-CoV-2) has been a major global challenge for the scientific community to save humanity. While, the unviability of the vaccine keeps most classes of society, especially African countries, suffer from the healthcare problem. Conventional medicine plants become the alternative method for the therapeutic because it contains valuable bioactive compounds. This brief review devoted the importance of medicinal plants such as Citrus, olive, garlic, ginger, green tea, woad, broad-leaf privet, Japanese torreya, and saffron crocus, by their antiviral effects (anti-SARS coronavirus, anti-HSV, and anti-HIV diseases) and their promising uses as probable boosters of the immune and anti-inflammatory response from SARS-CoV-2 infection. Based on scientific reports, bioactive compounds could inhibit 3-chymotrypsin-like cysteine protease and human protein ACE2, where these facts can be attractive to develop effective drugs.
The Potentials of Medicinal Plants in the Treatment of Covid-19 Patients: A Review
International Journal of Pharmacognosy & Chinese Medicine
COVID-19 pandemic (corona virus disease 2019 is a life threatening SARS-Cov-19 severe acute respiratory syndrome virus 2) situation that was declared a public health emergency by WHO in early 2020. Today’s primary emphasis is on the treatment of COVID-19 yet the specific mode of action of antiviral agents being employed must be identified. At present, the human on risk are being vaccinated but there is no clear anti-COVID 19 medicine. This study focuses on herbal approaches as a potential alternative therapy for COVID-19, based on medicinal plants. Some herbs are well-known in different traditional medicines for prevention, cure and recovery of the diseases like COVID-19. Mostly the plant’s herbal extract inhibits viral replication; however several studies have shown that conventional herbal extracts may interact with important viral proteins associated with the virulence. The update on traditional medicines suggested for the prevention of COVID-19 has been analyzed here.
Plant-Derived Secondary Metabolites as Potential Mediators against COVID-19: A Review
2020
The current pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has envisioned a global health concern The scientists and physicians around the world have been racing to understand the pathophysiology and possible treatment régimes to discover an effective therapeutic resolution against the disease Different secondary metabolites from plants exhibit substantial biological assets including antiviral activity These compounds may be used against the infections of coronavirus The research papers, reviews, and preprints were searched from the PubMed database using keywords like severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome (MERS), and traditional herbal medicine against COVID-19 The review focuses on those natural products which exhibited optimistic results against SARS-COV and SARS-CoV-2 in virtual as well as physical in vitro and in vivo tests It summarizes the epidemiological characters, pathogenesis,...
IntechOpen eBooks, 2022
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In an effort to combat the pandemic caused by COVID-19 disease, researchers have identified several traditional medicinal plants (TMPs) as potential adjuvant, prophylactic, and treatment for COVID-19. TMPs reported in this paper were identified based on the findings of molecular docking research and the documented traditional use of these plants for COVID-19-related symptoms, such as fever, coughing, headaches, and tiredness. Secondary metabolites with antiviral, anti-inflammatory, and immunomodulatory activity against various SARS-CoV-2 proteases were also identified from the list of South African medicinal plants. This review discusses secondary metabolites of TMPs with pharmacological benefits, which contribute to the management of COVID-19, and these include
Basrah Journal of Agricultural Sciences
The current COVID-19 pandemic is the main issue globally, and finding solutions either for disease prevention or treatment is nowadays a key scientific concern. Good immunity can be shown as the only proven method of overcoming or minimizing the adverse effects of virus infections. Since Coronavirus spread, different conventional herbs were used as a traditional medication to enhance people's immunity to combat the virus. Herbs are sources of several phytochemical compounds with compelling bioactivities. A review of the studies concerning herbal plants with proven properties against viral infections is highlighted in the present work. Besides, this work also contains some of the recently published studies related to natural herbs that could be highly beneficial in preventing or treating the infection by Coronavirus. Based on the reviewed literature presented in this update, it was concluded that phytochemical constituents found in many herbs could have a potential role in preven...
Natural Products from Medicinal Plants with Anti-Human Coronavirus Activities
Molecules, 2021
Since the emergence of severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2) first reported in Wuhan, China in December 2019, COVID-19 has spread to all the continents at an unprecedented pace. This pandemic has caused not only hundreds of thousands of mortalities but also a huge economic setback throughout the world. Therefore, the scientific communities around the world have focused on finding antiviral therapeutic agents to either fight or halt the spread of SARS-CoV-2. Since certain medicinal plants and herbal formulae have proved to be effective in treatment of similar viral infections such as those caused by SARS and Ebola, scientists have paid more attention to natural products for effective treatment of this devastating pandemic. This review summarizes studies and ethnobotanical information on plants and their constituents used for treatment of infections caused by viruses related to the coronavirus family. Herein, we provide a critical analysis of previous ...
Journal of Advances in Medicine and Medical Research, 2021
The menace of COVID-19 continues to ravage the world despite deployment of vaccines, and the development of oral antiviral pills whose effectiveness are still being evaluated. As the problems persist, Scientists are continuously searching for new resources and re-evaluating old ones that be used to effectively contain the pandemic. A search through literature has shown a huge amount of scientific resources in medicinal plant research which could be leverage. Many medicinal plants have been demonstrated to possess various antiviral activities against influenza virus, SARS-CoV, herpes simplex virus, vesicular stomatitis virus, hepatitis B virus, hepatitis C virus, human immunodeficiency virus, simian immunodeficiency virus, echovirus, adenovirus, Newcastle disease virus, duck plague virus, measles virus, polio viruses, yellow fever viruses, Sindbis virus, human cytomegalovirus, Rift valley fever virus, feline herpesvirus, lumpy skin disease virus, and canine distemper virus. Medicina...
Medicinal Plants as Sources of Active Molecules Against COVID-19
Frontiers in Pharmacology, 2020
The Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) or novel coronavirus (COVID-19) infection has been declared world pandemic causing a worrisome number of deaths, especially among vulnerable citizens, in 209 countries around the world. Although several therapeutic molecules are being tested, no effective vaccines or specific treatments have been developed. Since the COVID-19 outbreak, different traditional herbal medicines with promising results have been used alone or in combination with conventional drugs to treat infected patients. Here, we review the recent findings regarding the use of natural products to prevent or treat COVID-19 infection. Furthermore, the mechanisms responsible for this preventive or therapeutic effect are discussed. We conducted literature research using PubMed, Google Scholar, Scopus, and WHO website. Dissertations and theses were not considered. Only the situation reports edited by the WHO were included. The different herbal products (extracts) and purified molecules may exert their anti-SARS-CoV-2 actions by direct inhibition of the virus replication or entry. Interestingly, some products may block the ACE-2 receptor or the serine protease TMPRRS2 required by SARS-CoV-2 to infect human cells. In addition, natural products were shown to inhibit the SARS-CoV-2 life-cycle related proteins such as papain-like or chymotrypsin-like proteases. In conclusion, we suggest that natural products could be used alone or in combination as alternative medicines to treat/ prevent COVID-19 infection. Moreover, their structures may offer clues for the development of anti-SARS-CoV-2 drugs.