Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload (original) (raw)
Local Cytosolic Ca2+ Elevations Are Required for Stromal Interaction Molecule 1 (STIM1) De-oligomerization and Termination of Store-operated Ca2+ Entry
Wei Shen
Journal of Biological Chemistry, 2011
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Molecular Determinants for STIM1 Activation During Store- Operated Ca2+ Entry
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Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex
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STIM and Orai: Dynamic Intermembrane Coupling to Control Cellular Calcium Signals
Donald Gill
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STIM2 enhances receptor-stimulated Ca 2+ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum–plasma membrane junctions
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Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1
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Biochemical and Biophysical Research Communications, 2006
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Stim and Orai mediate constitutive Ca2+ entry and control endoplasmic reticulum Ca2+ refilling in primary cultures of colorectal carcinoma cells
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Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated Ca2+ entry
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Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry
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Maria Spassova
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Store-operated Ca2+ entry is sensitive to the extracellular Ca2+ concentration through plasma membrane STIM1
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Di-Arginine Signals and the K-Rich Domain Retain the Ca 2+ Sensor STIM1 in the Endoplasmic Reticulum
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Dynamic S-acylation of STIM1 is required for store-operated Ca2+ entry
Goutham Kodakandla
2022
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STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane
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