original ) (raw )Strategies to design pyrazolyl urea derivatives for p38 kinase inhibition: a molecular modeling study
Srivani Palukuri
Journal of Computer-Aided Molecular Design, 2007
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Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796)
Jeffrey Madwed
Journal of Medicinal Chemistry, 2003
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Dibenzepinones, dibenzoxepines and benzosuberones based p38α MAP kinase inhibitors: Their pharmacophore modelling, 3D-QSAR and docking studies
Mohemmed Faraz Khan
Computers in Biology and Medicine, 2019
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Evaluation of the combination mode and features of p38 MAPK inhibitors: construction of different pharmacophore models and molecular docking
liyu zhao
Molecular Simulation, 2019
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Discovery and characterization of the N-phenyl-N′-naphthylurea class of p38 kinase inhibitors
Jeffrey Madwed
Bioorganic & Medicinal Chemistry Letters, 2009
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Pyrazole Urea-Based Inhibitors of p38 MAP Kinase: From Lead Compound to Clinical Candidate
Jeffrey Madwed
Journal of Medicinal Chemistry, 2002
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New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site
Jeffrey Madwed
Bioorganic & Medicinal Chemistry Letters, 2007
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p38 MAP kinase inhibitors. Part 6: 2-Arylpyridazin-3-ones as templates for inhibitor design
Giovanna Scapin
Bioorganic & Medicinal Chemistry Letters, 2006
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Dissection of the Recognition Properties of p38 MAP Kinase. Determination of the Binding Mode of a New Pyridinyl−Heterocycle Inhibitor Family
Modesto Orozco
Journal of Medicinal Chemistry, 2007
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Design, Synthesis and Biological Evaluation of Chromone-based p38 MAP Kinase Inhibitors
Linda Linda
Journal of Medicinal Chemistry, 2011
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The Discovery of Orally Active Triaminotriazine Aniline Amides as Inhibitors of p38 MAP Kinase
jeffrey letourneau
Journal of Medicinal Chemistry, 2004
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1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors
Holia Hatoummokdad , Ajay Bhargava
Bioorganic & Medicinal Chemistry Letters, 2000
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Pharmacophore modeling of diverse classes of p38 MAP kinase inhibitors
Kishore Ravikumar
European Journal of Medicinal Chemistry, 2008
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ACCOUNT 1564ű 1564 account Process Research and Development for Heterocyclic p38 MAP Kinase Inhibitors Heterocyclic p38 MAP Kinase Inhibitor s
ramu reddy
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Docking and 3D QSAR Studies on p38α MAP Kinase Inhibitors
Vijjulatha Manga
E-Journal of Chemistry, 2011
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Synthesis, characterization, in vitro anticancer activity, and docking of Schiff bases of 4-amino-1,2-naphthoquinone
Meenakshi Singh
Medicinal Chemistry Research, 2012
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Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase ⊥ ⊥ Atomic coordinates and structure factors for crystal structure of compound 3d with p38α can be accessed using PDB code 3LHJ
Helen McBride , Ryan Wurz
Journal of Medicinal Chemistry, 2010
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Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening
Nihar Das
Journal of Molecular Graphics and Modelling, 2014
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Synthesis and SAR of p38α MAP kinase inhibitors based on heterobicyclic scaffolds
Gary Schieven
Bioorganic & Medicinal Chemistry Letters, 2007
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Complex Structure Modeling of p38 MAP Kinase and Pyridyl-pyrrole Compounds
Shuichi Miyamoto
Chem-Bio Informatics Journal, 2001
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Synthesis and Biological Evaluation of Urea Derivatives as Highly Potent and Selective Rho Kinase Inhibitors
Y. Yin , Yangbo Feng
Journal of Medicinal Chemistry, 2013
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Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase
Kevin D Jerome , Jeff Hitchcock , Brian Hickory
Bioorganic & Medicinal Chemistry Letters, 2011
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Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38α MAP kinase inhibitors
Jeffrey Tredup , Gary Schieven
Bioorganic & Medicinal Chemistry Letters, 2008
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Amide-based inhibitors of p38α MAP kinase. Part 2: Design, synthesis and SAR of potent N-pyrimidyl amides
Xuefei Tan
Bioorganic & Medicinal Chemistry Letters, 2010
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Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase
Brian Hickory , Kevin D Jerome , Jeff Hitchcock
Bioorganic & Medicinal Chemistry Letters, 2011
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Syntheses and structure–activity relationships for some triazolyl p38α MAPK inhibitors
Jean-Paul Seerden
Bioorganic Medicinal Chemistry Letters, 2014
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