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A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole

David Calabrese

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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14a-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

Dominique Sanglard

1998

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Overexpression of the MDR1 Gene Is Sufficient To Confer Increased Resistance to Toxic Compounds in Candida albicans

Dominique Sanglard

Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER, 2006

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Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals

Dominique Sanglard, Jamel Eddouzi, Alix Coste, Luís Vale-Silva

Antimicrobial Agents and Chemotherapy, 2013

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Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis

Patrick Van Dijck

Antimicrobial Agents and Chemotherapy, 2012

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CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain ofCandida albicans

Vinita Gupta

Yeast, 2001

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Rep1p negatively regulating MDR1 efflux pump involved in drug resistance in Candida albicans

Ci-hong Liou

Fungal Genetics and Biology, 2009

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Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors

Pooja Jain

Antimicrobial Agents and Chemotherapy, 2003

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The Phenotypic Consequences of a Spontaneous Loss of Heterozygosity in a Common Laboratory Strain of Candida Albicans

Judith Berman

Genetics, 2016

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A single SNP, G929T (Gly310Val), determines the presence of a functional and a non-functional allele of HIS4 in Candida albicans SC5314: Detection of the non-functional allele in laboratory strains

Germán Larriba, Jonathan Gómez-Raja, Beatrice Magee

Fungal Genetics and Biology, 2008

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Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates

Alix Coste

Eukaryotic Cell, 2007

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Azole Resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the Role of ERG11

Igor Bruzual

Antimicrobial Agents and Chemotherapy, 2013

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A Mutation in Tac1p, a Transcription Factor Regulating CDR1 and CDR2, Is Coupled With Loss of Heterozygosity at Chromosome 5 to Mediate Antifungal Resistance in Candida albicans

Judith Berman

Genetics, 2005

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Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Mikhail Keniya

Journal of Fungi

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Genome-Wide Single-Nucleotide Polymorphism Map for Candida albicans

Beatrice Magee

Eukaryotic Cell, 2004

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Aneuploid Chromosomes Are Highly Unstable during DNA Transformation of Candida albicans

Judith Berman

Eukaryotic Cell, 2009

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A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance

Dominique Sanglard

Molecular Microbiology, 2002

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Isogenic Strain Construction and Gene Targeting in Candida dubliniensis

Derek Sullivan

Journal of Bacteriology, 2001

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Conserved Fungal Genes as Potential Targets for Broad-Spectrum Antifungal Drug Discovery

Robert Bruccoleri

Eukaryotic Cell, 2006

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Systematic truncations of chromosome 4 and their responses to antifungals in Candida albicans

Darshan Dhabalia

Journal of Genetic Engineering & Biotechnology, 2021

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Disruption studies of a Candida albicans gene, ELF1: a member of the ATP-binding cassette family

Richard Calderone

Microbiology, 1998

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Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection

Alix Coste

Antimicrobial Agents and Chemotherapy, 2010

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The Roles of Hsp90 and Calcineurin in Antifungal Drug Resistance

Sheena Singh

2012

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Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

Dominique Sanglard

Antimicrobial Agents and Chemotherapy, 2003

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Functional Similarities and Differences between Candida albicans Cdr1p and Cdr2p Transporters

elias georges

Antimicrobial Agents and Chemotherapy, 2003

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TAC1, Transcriptional Activator of CDR Genes, Is a New Transcription Factor Involved in the Regulation of Candida albicans ABC Transporters CDR1 and CDR2

Dominique Sanglard, Alix Coste

Eukaryotic Cell, 2004

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Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

mk vyas

Antimicrobial Agents and Chemotherapy, 2005

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The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin

Birgit Willinger

Molecular Microbiology, 2003

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Overexpression of a dominant-negative allele of YPT1 inhibits growth and aspartyl protease secretion in Candida albicans

Vernon Kalb

Microbiology (Reading, England), 2001

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Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans

Yun-liang Yang

Antimicrobial Agents and Chemotherapy, 2005

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An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

Judith Berman

2008

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Molecular Mechanism of Terbinafine Resistance in Saccharomyces cerevisiae

Christoph Ruckenstuhl

Antimicrobial Agents and Chemotherapy, 2003

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

Karl Kuchler

Antimicrobial Agents and Chemotherapy, 1995

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Heterologous expression of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provides tools for antifungal discovery

Mikhail Keniya

Antimicrobial Agents and Chemotherapy, 2018

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Analysis of heterologous expression of Candida albicans SEC61 gene reveals differences in Sec61p homologues related to species-specific functionality

Luis Carlos Udaeta Rodriguez

Fungal Genetics and Biology, 2004

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