A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole
David Calabrese
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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14a-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents
Dominique Sanglard
1998
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Overexpression of the MDR1 Gene Is Sufficient To Confer Increased Resistance to Toxic Compounds in Candida albicans
Dominique Sanglard
Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER, 2006
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Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals
Dominique Sanglard, Jamel Eddouzi, Alix Coste, Luís Vale-Silva
Antimicrobial Agents and Chemotherapy, 2013
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Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis
Patrick Van Dijck
Antimicrobial Agents and Chemotherapy, 2012
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CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain ofCandida albicans
Vinita Gupta
Yeast, 2001
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Rep1p negatively regulating MDR1 efflux pump involved in drug resistance in Candida albicans
Ci-hong Liou
Fungal Genetics and Biology, 2009
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Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors
Pooja Jain
Antimicrobial Agents and Chemotherapy, 2003
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The Phenotypic Consequences of a Spontaneous Loss of Heterozygosity in a Common Laboratory Strain of Candida Albicans
Judith Berman
Genetics, 2016
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A single SNP, G929T (Gly310Val), determines the presence of a functional and a non-functional allele of HIS4 in Candida albicans SC5314: Detection of the non-functional allele in laboratory strains
Germán Larriba, Jonathan Gómez-Raja, Beatrice Magee
Fungal Genetics and Biology, 2008
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Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates
Alix Coste
Eukaryotic Cell, 2007
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Azole Resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the Role of ERG11
Igor Bruzual
Antimicrobial Agents and Chemotherapy, 2013
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A Mutation in Tac1p, a Transcription Factor Regulating CDR1 and CDR2, Is Coupled With Loss of Heterozygosity at Chromosome 5 to Mediate Antifungal Resistance in Candida albicans
Judith Berman
Genetics, 2005
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Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate
Mikhail Keniya
Journal of Fungi
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Genome-Wide Single-Nucleotide Polymorphism Map for Candida albicans
Beatrice Magee
Eukaryotic Cell, 2004
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Aneuploid Chromosomes Are Highly Unstable during DNA Transformation of Candida albicans
Judith Berman
Eukaryotic Cell, 2009
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A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance
Dominique Sanglard
Molecular Microbiology, 2002
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Isogenic Strain Construction and Gene Targeting in Candida dubliniensis
Derek Sullivan
Journal of Bacteriology, 2001
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Conserved Fungal Genes as Potential Targets for Broad-Spectrum Antifungal Drug Discovery
Robert Bruccoleri
Eukaryotic Cell, 2006
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Systematic truncations of chromosome 4 and their responses to antifungals in Candida albicans
Darshan Dhabalia
Journal of Genetic Engineering & Biotechnology, 2021
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Disruption studies of a Candida albicans gene, ELF1: a member of the ATP-binding cassette family
Richard Calderone
Microbiology, 1998
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Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection
Alix Coste
Antimicrobial Agents and Chemotherapy, 2010
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The Roles of Hsp90 and Calcineurin in Antifungal Drug Resistance
Sheena Singh
2012
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Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents
Dominique Sanglard
Antimicrobial Agents and Chemotherapy, 2003
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Functional Similarities and Differences between Candida albicans Cdr1p and Cdr2p Transporters
elias georges
Antimicrobial Agents and Chemotherapy, 2003
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TAC1, Transcriptional Activator of CDR Genes, Is a New Transcription Factor Involved in the Regulation of Candida albicans ABC Transporters CDR1 and CDR2
Dominique Sanglard, Alix Coste
Eukaryotic Cell, 2004
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Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates
mk vyas
Antimicrobial Agents and Chemotherapy, 2005
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The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin
Birgit Willinger
Molecular Microbiology, 2003
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Overexpression of a dominant-negative allele of YPT1 inhibits growth and aspartyl protease secretion in Candida albicans
Vernon Kalb
Microbiology (Reading, England), 2001
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Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans
Yun-liang Yang
Antimicrobial Agents and Chemotherapy, 2005
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An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
Judith Berman
2008
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Molecular Mechanism of Terbinafine Resistance in Saccharomyces cerevisiae
Christoph Ruckenstuhl
Antimicrobial Agents and Chemotherapy, 2003
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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
Karl Kuchler
Antimicrobial Agents and Chemotherapy, 1995
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Heterologous expression of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provides tools for antifungal discovery
Mikhail Keniya
Antimicrobial Agents and Chemotherapy, 2018
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Analysis of heterologous expression of Candida albicans SEC61 gene reveals differences in Sec61p homologues related to species-specific functionality
Luis Carlos Udaeta Rodriguez
Fungal Genetics and Biology, 2004
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