Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate (original ) (raw )Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase
Mikhail Keniya
Antimicrobial Agents and Chemotherapy
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The Mutation T315A in Candida albicans Sterol 14α-Demethylase Causes Reduced Enzyme Activity and Fluconazole Resistance through Reduced Affinity
muhammad saeed Akhtar
Journal of Biological Chemistry, 1997
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Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans
Marcel Borgers , Hugo Vanden Bossche
Microbiology (Reading, England), 1999
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Genetic Analysis of Azole Resistance in the Darlington Strain of Candida albicans
Brian Grimberg
Antimicrobial Agents and Chemotherapy, 2000
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Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450
Osamu Gotoh
Antimicrobial agents and chemotherapy, 1999
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Formation of Azole-Resistant Candida albicans by Mutation of Sterol 14-Demethylase P450
Osamu Gotoh
Antimicrobial Agents and Chemotherapy, 1999
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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14a-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents
Dominique Sanglard
1998
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The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance
Audrey FLEURY
Medical mycology, 2016
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Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
Florent Morio
Diagnostic microbiology and infectious disease, 2010
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Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection
Alix Coste
Antimicrobial Agents and Chemotherapy, 2010
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Mechanisms of Azole Resistance in Petite Mutants of Candida glabrata
dominique CHABASSE
Antimicrobial Agents and Chemotherapy, 2004
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Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161
Mikhail Keniya
Antimicrobial Agents and Chemotherapy
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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents
Dominique Sanglard
Antimicrobial Agents and Chemotherapy, 1998
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Amino acid substitutions in the Candida albicans sterol Δ5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence
Florent Morio
Journal of Antimicrobial Chemotherapy
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Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans
M. Weig
Antimicrobial Agents and Chemotherapy, 2010
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Azole Resistance by Loss of Function of the Sterol Δ 5,6 -Desaturase Gene ( ERG3 ) in Candida albicans Does Not Necessarily Decrease Virulence
Dominique Sanglard
Antimicrobial Agents and Chemotherapy, 2012
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Molecular mechanisms of azole resistance in Candida bloodstream isolates
Andrea Kwa
BMC Infectious Diseases
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Multiple resistance mechanisms to azole antifungals in yeast clinical isolates
David Calabrese
Drug Resistance Updates, 1998
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Copyright © 1997, American Society for Microbiology Molecular Biological Characterization of an Azole-Resistant
Hugo Vanden Bossche
1997
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Amino Acid Substitutions at the Major Insertion Loop of Candida albicans Sterol 14alpha-Demethylase Are Involved in Fluconazole Resistance
Florent Morio
PLoS ONE, 2011
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Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates
Surajit Debnath
SpringerPlus, 2014
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Disclosing azole resistance mechanisms in resistant Candida glabrata strains encoding wild-type or gain-of-function CgPDR1 alleles through comparative genomics and transcriptomics
vitoria rodrigues
G3 Genes|Genomes|Genetics
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Azole susceptibility and resistance in Candida dubliniensis
Derek Sullivan
Biochemical Society Transactions, 2005
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Insights into the Multi-Azole Resistance Profile in Candida haemulonii Species Complex
Eamim Daidre Squizani
Journal of Fungi, 2020
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Heterologous expression of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provides tools for antifungal discovery
Mikhail Keniya
Antimicrobial Agents and Chemotherapy, 2018
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Differential Azole Antifungal Efficacies Contrasted Using a Saccharomyces cerevisiae Strain Humanized for Sterol 14α-Demethylase at the Homologous Locus
Denis POMPON
Antimicrobial Agents and Chemotherapy, 2008
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Reduced Azole Susceptibility in Genotype 3 Candida dubliniensis Isolates Associated with Increased CdCDR1 and CdCDR2 Expression
Derek Sullivan
Antimicrobial Agents and Chemotherapy, 2005
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Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates
Alix Coste
Eukaryotic Cell, 2007
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Rapid detection of ERG11 polymorphism associated azole resistance in Candida tropicalis
Shreya Singh
PLOS ONE, 2021
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