Common Genetic Variants of the Human Steroid 21-Hydroxylase Gene (CYP21A2) Are Related to Differences in Circulating Hormone Levels (original) (raw)

p.H62L, a Rare Mutation of the CYP21 Gene Identified in Two Forms of 21-Hydroxylase Deficiency

Jean-Pierre BROSSIER

The Journal of Clinical Endocrinology & Metabolism, 2008

View PDFchevron_right

CYP21 gene mutations in Brazilian patients with 21-hydroxylase deficiency from the Amazon region

MILENA CALDATO

Genetics and Molecular Biology, 2008

View PDFchevron_right

Normal Gestation and Diminished Androgen Responsiveness in an Untreated Patient with 21-Hydroxylase Deficiency

Laurence Jacobs

The Journal of Clinical Endocrinology & Metabolism, 1976

View PDFchevron_right

Late-onset 21-hydroxylase deficiency: Reliable diagnosis by steroid analysis of random urine collections

Julian Irias

Steroids, 1986

View PDFchevron_right

Frequency of CYP21 Gene Mutations in Czech Patients with Steroid 21-Hydroxylase Deficiency and Statistical Comparison with Other Populations

Karel Kotaska

Medical Principles and Practice, 2003

View PDFchevron_right

The presence of the 21-hydroxylase deficiency carrier status in hirsute women: phenotype-genotype correlations

Jose Sancho

Fertility and Sterility, 1999

View PDFchevron_right

Aromatase Deficiency due to a Novel Mutation in CYP19A1 Gene

Yusuf Kenan Haspolat

Journal of Clinical Research in Pediatric Endocrinology, 2018

View PDFchevron_right

Two Novel Mutations with 17 Hydroxylase Deficiency – Alpha and Beta Presenting as 46XY Disorders of Sexual Development

nikhil lohiya

Indian Journal of Child Health, 2019

View PDFchevron_right

Estrogen-Metabolizing Gene Polymorphisms, Genetic Susceptibility, and Pharmacogenomics

Johannes Ott

The Role of Genetics in Breast and Reproductive Cancers, 2009

View PDFchevron_right

Occurrence of CYP17A1 Gene Mutations in the 17Α-HYDROXYLASE in Pakistanis Population

Rana Muhammad Qasim

2020

View PDFchevron_right

CYP11B1 mutations causing congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency

Karin Jöhrer

The Journal of Clinical Endocrinology & Metabolism, 1996

View PDFchevron_right

Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status

Vita Dolzan

European Journal of Endocrinology, 1999

View PDFchevron_right

Mutations of the 5α-Steroid Reductase Type 2 Gene in Six Turkish Patients from Unrelated Families and a Large Pedigree of an Isolated Turkish Village

Z. Aycan

Journal of Pediatric Endocrinology and Metabolism, 2002

View PDFchevron_right

Analysis of the chimeric CYP21P/CYP21 gene in steroid 21-hydroxylase deficiency

Bon-chu Chung

Clinical …, 2000

View PDFchevron_right

Polymorphisms in the P450 c17 (17-Hydroxylase/17,20-Lyase) and P450 c19 (Aromatase) Genes: Association with Serum Sex Steroid Concentrations and Bone Mineral Density in Postmenopausal Women

Geeta Hampson

The Journal of Clinical Endocrinology & Metabolism, 2004

View PDFchevron_right

Linkage analysis of the C4A/ C4B copy number variation and polymorphisms of the adjacent steroid 21-hydroxylase gene in a healthy population

Katalin Rajczy

Molecular Immunology, 2009

View PDFchevron_right

Molecular genetics of human chromosome 21

Rudy Tanzi

Journal of Medical Genetics, 1987

View PDFchevron_right

The Genetics of Steroid 21-Hydroxylase Deficiency

Javier Aisenberg

The Endocrinologist, 2005

View PDFchevron_right

Characterization of mutations on the rare duplicated C4/CYP21 haplotype in steroid 21-hydroxylase deficiency

Holger Luthman

Human Genetics, 1994

View PDFchevron_right

Differences in hormonal levels between heterozygous CYP21A2 pathogenic variant carriers, non-carriers, and females with non-classic congenital hyperplasia

Cíntia Castro-Correia

Archives of Endocrinology and Metabolism, 2022

View PDFchevron_right

Characterization of mutations causing steroid 21-hydroxylase deficiency in Brazilian and Portuguese populations

Thaiane Rispoli

bioRxiv, 2021

View PDFchevron_right

Pharmacogenetics of human androgens and prostatic diseases

Giuseppe Novelli

Pharmacogenomics, 2001

View PDFchevron_right

Using Real-Time, Quantitative PCR for Rapid Genotyping of the Steroid 21-Hydroxylase Gene in a North Florida Population

Jianwei Wang

The Journal of Clinical Endocrinology & Metabolism, 2002

View PDFchevron_right

Mutation detection of CYP21A2 gene in nonclassical congenital adrenal hyperplasia patients with premature pubarche

Arman Ansari

Advanced Biomedical Research, 2016

View PDFchevron_right

High Frequency of Nonclassical Steroid 21-Hydroxylase Deficiency

Phyllis Speiser

Obstetrical & Gynecological Survey, 1986

View PDFchevron_right

Steroid 21‐hydroxylase gene mutational spectrum in 454 Argentinean patients: genotype–phenotype correlation in a large cohort of patients with congenital adrenal hyperplasia

noura zouari

Clinical Endocrinology, 2011

View PDFchevron_right

Genetic causes of combined pituitary hormone deficiencies in humans

Thierry Brue

Annales d'Endocrinologie, 2012

View PDFchevron_right

Nonclassic Steroid 21-Hydroxylase Deficiency due to a Homozygous V281L Mutation in CYP21A2 Detected by the Neonatal Mass-Screening Program in Japan

Reiko Horikawa

Endocrine Journal, 2007

View PDFchevron_right

Naturally Occurring Mutants of Human Steroid 21-Hydroxylase (P450c21) Pinpoint Residues Important for Enzyme Activity and Stability

Holger Luthman

Journal of Biological Chemistry, 1998

View PDFchevron_right

Principles of Endocrinology and Hormone Action

Paco G. López

View PDFchevron_right

Genomics of steroid hormones: in silico analysis of nucleotide sequence variants (polymorphisms) of the enzymes involved in the biosynthesis and metabolism of steroid hormones

Peter Igaz

The Journal of steroid biochemistry and molecular biology, 2002

View PDFchevron_right

High Frequency of Copy Number Variations and Sequence Variants at CYP21A2 Locus: Implication for the Genetic Diagnosis of 21-Hydroxylase Deficiency

Fernando Dominguez

PLoS ONE, 2008

View PDFchevron_right

Exon 7 Nco l Restriction Site within CYP21B (Steroid 21-Hydroxylase) Is a Normal Polymorphism

Rodrigo Neto

Molecular Endocrinology, 1990

View PDFchevron_right