Quantitative and Qualitative Adjustment of Thymic T Cell Production by Clonal Expansion of Premigrant Thymocytes
Bruno Lucas
The Journal of Immunology, 2002
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Stage-dependent reactivity of thymocytes to self-peptide–MHC complexes
Jianzhu Chen
Proceedings of the National Academy of Sciences, 2007
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Affinity of thymic self-peptides for the TCR determines the selection of CD8+ T lymphocytes in the thymus
Joseph Opferman
International Immunology, 2000
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Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells
Osami Kanagawa
Journal of immunology (Baltimore, Md. : 1950), 1999
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The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery
J. Sprent
Immunity, 1999
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Preselection Thymocytes Are More Sensitive to T Cell Receptor Stimulation Than Mature T Cells
Stephen Jameson
Journal of Experimental Medicine, 1998
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Differential processing of self-antigens by subsets of thymic stromal cells
Hervé Luche
Current Opinion in Immunology, 2012
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Pre-T cell receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation
Cameron Messier
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Role of thymic cortex-specific self-peptides in positive selection of T cells
Takeshi Nitta
Seminars in Immunology, 2010
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The frequency of double-positive thymocytes expressing an alphabeta TCR clonotype regulates peripheral CD4 T cell compartment homeostasis
Hooman Noorchashm, Ali Naji
Immunology, 2005
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Specific Recognition of Thymic Self-Peptides Induces the Positive Selection of Cytotoxic T Lymphocytes
Joseph Opferman
Immunity, 1997
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T Cell Tolerance and the Thymusa
J. Sprent
Annals of the New York Academy of Sciences, 1998
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Signaling Life and Death in the Thymus: Timing Is Everything
Ed Palmer
Science, 2003
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Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells
Pradyot Dash
Proceedings of the National Academy of Sciences, 2011
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Thymic Selection Generates T Cells Expressing Self-Reactive TCRs in the Absence of CD45
S. Trop
The Journal of Immunology, 2000
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Divergent Changes in the Sensitivity of Maturing T Cells to Structurally Related Ligands Underlies Formation of a Useful T Cell Repertoire
Bruno Lucas
Immunity, 1999
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Rare, Structurally Homologous Self-Peptides Promote Thymocyte Positive Selection
Stephen Jameson
Immunity, 2002
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The thymus has two functionally distinct populations of immature αβ+ T cells: One population is deleted by ligation of αβTCR
Willi Born
Cell, 1989
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Toward Understanding How the Immune System Establishes a Diverse Yet Self-Tolerant T-Cell Repertoire: Stepwise Roles of Thymic Microenvironments
Takeshi Nitta
Systems Biology, 2009
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Alteration of T-cell Receptor Repertoires During Thymic T-cell Development
Takeshi Yoshioka
Scandinavian Journal of Immunology, 2006
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Evidence for a selective and multi-step model of T cell differentiation: CD4+CD8low thymocytes selected by a transgenic T cell receptor on major histocompatibility complex class I molecules
Richard Boyd
European Journal of Immunology, 1994
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Self-Tolerance and the Composition of T Cell Repertoire
Anwar Murtaza
Immunologic Research, 2000
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Thymocytes Positively Select Thymocytes in Human System
Jon Kim
Human Immunology, 1997
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Premature TCR Expression and Signaling in Early Thymocytes Impair Thymocyte Expansion and Partially Block Their Development
Ljiljana Vasovic
The Journal of Immunology, 2001
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Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation
Gilles Marodon
European Journal of Immunology, 1994
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MHC class I is required for peripheral accumulation of CD8+ thymic emigrants
Dragana Nesic
Journal of immunology (Baltimore, Md. : 1950), 1998
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Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides
Mitchell Kronenberg
Immunity, 2002
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Functional CD8 + but not CD4 + T cell responses develop independent of thymic epithelial MHC
Edit Horvath
Proceedings of the National Academy of Sciences, 2006
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Defined T Cell Receptors with Distinct Ligand Specificities Do Not Require Those Ligands to Signal Double Negative Thymocyte Differentiation
B. Erman
Journal of Experimental Medicine, 2004
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Thymocyte-intrinsic genetic factors influence CD8 T cell lineage commitment and affect selection of a tumor-reactive TCR
Benoit Van den Eynde
The Journal of …, 2004
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Early Molecular Events Induced by T Cell Receptor (TCR) Signaling in Immature CD4 + CD8 + Thymocytes: Increased Synthesis of TCR-c~ Protein Is an Early Response to TCR Signaling That Compensates for TCR-c~ Instability, Improves TCR Assembly, and Parallels Other Indicators of Positive Selection
Kelly Kearse
2000
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TCR repertoire selection in the thymus and peripheral T cell
Alexander Fleming
2007
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Age-Dependent TCR Revision Mediated by Interaction between TCR and Self-Antigens
Osami Kanagawa
The Journal of Immunology, 2007
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Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing
Klaus Rajewsky
Immunity, 2002
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Peripheral Expression of Self-MHC-II Influences the Reactivity and Self-Tolerance of Mature CD4+ T Cells
A. Bhandoola
Immunity, 2002
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