Phytochemical Screening and Antimicrobial Activity Of Asparagus Racemosus Willd. and Asparagus Curillus Buch.-Ham. Ex Roxb (original) (raw)
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2017
Asparagus racemosus Willd. is an important medicinal plant of tropical and subtropical regions of Nepal and India. Its medicinal usage has been reported in the Indian and British Pharmacopoeias and in traditional systems of medicine such as Ayurveda, Unani, and Siddha. Asparagus curillus Buch-Ham.ex Roxb. is also one of the species found in higher altitude of Nepal. Its roots are used as substitute for A. racemosus. Phytochemical investigation was done for these two species of Nepalese Asparagus as per Methodology for Analysis of Vegetable Drugs by I. Ciulei.1982. Phytochemical screening revealed the presence of coumarin, flavonoid, catecholic tannin, reducing compound in alcoholic extract of A. racemosus while its aqueous extract revealed polyuronoid, reducing compound, polyoses, saponin, gallic tannin, catecholic tannin, etc. Similarly, alcoholic extract of A. curillus revealed catecholic tannin, reducing compound and aqueous extract revealed polyuronoid polyoses, saponin, gallic ...
2018
Asparagus racemosus Willd belongs to family Asparagaceae is a common medicinal plant found in hilly and plane regions of India. The plant has got immense medicinal properties and because of that it has got special importance in ayurvedic system of medicine. In the present investigation attempts were made for study of phytochemical and antibacterial activity of ethanolic extract of root. The study showed presence of primary phytochemicals like steroids, alkaloids, saponins, carbohydrates, flavoniods, amino acids except tannins. Chromatographic analysis (HPTLC) showed presence of seven polyvalent phytochemical compounds with variable Rf valus and concentration. The antimicrobial study of extract showed significant growth inhibition against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis Streptococcus pyogenes, Streptococcus pneumoniae and Pseudomonas aeruginosa. The mixture of polyvalent compounds present in the extracts might be responsible for the antibacterial a...
Tropical Plant Research, 2015
Plants are the base of sophisticated traditional medicine systems including Ayurvedic, Unani and Siddha. Phytochemical analysis of Asparagus racemosus revealed that numerous compounds of plants traditionally used for medicinal purposes have several therapeutical properties. The result of the phytochemical studies revealed the presence of saponins, tannins, alkaloids, steroids and other biochemicals. Saponins, tannins and alkaloids are well known for their antibacterial properties. Experiments demonstrating the pharmacological properties of saponins have aroused considerable clinical interest in these substances. The concentrations of the plant used were 25 mg ml-1 , 50 mg ml-1 and 100 mg ml-1 respectively. At these concentrations, the extract inhibited the growth of Escherichia coli, Pseudomonas aeruginosa and Vibrio parahaemolyticus and produced percentage inhibition ranging from 72.4-86.5 %. The antibacterial activity demonstrated by the plant extract may due to the presence of the phytochemicals present in the plant.
International Journal of Herbal Medicine, 2016
Aromatic and medicinal plants have played key roles in the lives of tribal peoples living in the Himalaya by providing products for both food and medicine. Asparagus racemosus (Asparagaceae) is an important medicinal plant of tropical and subtropical India. Its medicinal usage has been reported in the Indian and British Pharmacopoeias and in traditional systems of medicine such as Ayurveda, Unani and Siddha. Asparagus racemosus has been described to use as antioxidant, immune stimulant, anti-dyspepsia and anti-tussive effects. It is also useful in treatment of epilepsy, kidney disorders, chronic fevers, excessive heat, stomach ulcers and liver cancer, increases milk secretion in nursing mothers and regulates sexual behaviors. The major active constituents of Asparagus racemosus are steroidal saponins. Isoflavones, asparagamine, racemosol, polysaccharides, mucilage, vitamins A, B1, B2, C, E, Mg, P, Ca, Fe, and folic acid present in roots. Other primary chemical constituents of Aspara...
International journal of Pharmacy and Pharmaceutical Sciences, 2014
Objectives: Asparagus racemosus (AR) Willd, is commonly known as Shatavari, belongs to family Liliaceae, and has potent medicinal values. The present study deals with detail Pharmacological evaluation of ethanol fraction of AR. Methods: Preliminary phytochemical screening, antimicrobial and antioxidant activity, qualitative analysis of antioxidant and flavonoid detection, total phenol and flavonoid content were measured. Results: Phytochemical screening showed the presence of various phytoconstituents like phytosterols, phenols, flavonoids, saponins and carbohydrates. Ethanol fraction of Asparagus racemosus roots have maximum relative percentage inhibition against gram (-) bacteria. The root displayed significant DPPH free radical scavenging activity against standard ascorbic acid. Thin layer chromatography of the ethanol fraction was also performed to determine the active principles. Four major spots obtained with the Rf values 0.20, 0.22, 0.24 and 0.58. Total flavonoid and phenol content was 188.3 mg/g quercetin equivalent and 165.22mg/g gallic acid equivalent respectively. Conclusion: The findings of the current study shows that Asparagus racemosus is a good source of various phytochemicals and can be useful to progress and surge further scientific investigation to prevent and management of different diseases by their medicinal properties.
Phytochemical, Antioxidant and Antimicrobial Screening of Roots of Asparagus racemosus Willd.
World Journal of Pharmaceutical Research, 4(4): 709-722, 2015
The study deals with qualitative and quantitative phytochemical evaluation of bioactive phytochemicals of roots of Asparagus racemosus, a traditionally acclaimed medicinal plant and antioxidant and antimicrobial assays of root extracts. The physicochemical and phytochemical analysis including quantitative estimation of total steroidal saponins, total alkaloid, flavonoids and TLC profiling of various extracts of A. racemosus roots were done by prescribed methods. The antioxidant activity of methanol extract was performed as reducing power assay and antimicrobial activity of water extract was assayed against Staphylococcus inoculums. Physicochemical studies resulted in standard value of certain quality ascertaining parameters. Phytochemical screening indicated the presence of various phytochemicals. Quantitative evaluation of major bioactive constituents revealed considerably high content of total steroidal saponins in roots. Methanol extract of roots recorded a high amount of total phenolics and resultant good reducing activity whereas water extract of roots found to exhibit antibacterial activity against Staphylococcus. Standard values for key quality parameters will be helpful in authentication of A. racemosus roots. Notable antioxidant and antimicrobial activities of root extracts provide scientific validation of traditional medicinal claims of the plant.
International Journal of Pharmacy and Pharmaceutical Sciences, 2014
Objectives: Asparagus racemosus (AR) Willd, is commonly known as Shatavari, belongs to family Liliaceae, and has potent medicinal values. The present study deals with detail Pharmacological evaluation of ethanol fraction of AR. Methods: Preliminary phytochemical screening, antimicrobial and antioxidant activity, qualitative analysis of antioxidant and flavonoid detection, total phenol and flavonoid content were measured. Results: Phytochemical screening showed the presence of various phytoconstituents like phytosterols, phenols, flavonoids, saponins and carbohydrates. Ethanol fraction of Asparagus racemosus roots have maximum relative percentage inhibition against gram (-) bacteria. The root displayed significant DPPH free radical scavenging activity against standard ascorbic acid. Thin layer chromatography of the ethanol fraction was also performed to determine the active principles. Four major spots obtained with the Rf values 0.20, 0.22, 0.24 and 0.58. Total flavonoid and phenol content was 188.3 mg/g quercetin equivalent and 165.22mg/g gallic acid equivalent respectively. Conclusion: The findings of the current study shows that Asparagus racemosus is a good source of various phytochemicals and can be useful to progress and surge further scientific investigation to prevent and management of different diseases by their medicinal properties.
A Review on Pharmacological and Phytochemical Profile of Asparagus racemosus Willd
unisa.it
Ayurveda, an orthodox as well as main stream system of medicine has been with a source of new concepts and products for healthcare. Asparagus racemosus Willd. is an advantageously authenticated medicinal plant as observable from the literature. A. racemosus has also been used successfully by some Ayurvedic practitioners for inflammation, hepatic disorders, neurological disorder and certain infectious diseases. This study is a collective information concerning the ethnobotany, pharmacology, phytochemistry and biological activities of the Asparagus racemosus Willd.
Phytochemical studies and in vitro activity of Asparagus racemosus
Journal of Nepal Pharmaceutical Association, 2012
Phytochemical and biological screening of root of Asparagus racemosus was studied. The brine shrimp bioassay of its various extracts showed that the methanol (MeOH) extract was biologically active. The column chromatography of hexane, acetone and methanol extracts resulted in the isolation of 9- hexadecanoic acid-9-octadecenylester (Z,Z), ?-Sitosterol, stigmasterol-3-O-?-D-glucopyranoside and diosgenin. The estimation of saponin in the root of Asparagus racemosus has also been carried out.DOI: http://dx.doi.org/10.3126/jnpa.v26i1.6632JNPA. XXVI(1) 2012 48-53
Asparagus racemosus: The plant with immense medicinal potential
Journal of Pharmacognosy and Phytochemistry, 2018
The genus Asparagus belonging to the family liliaceae. The Asparagus racemosus (Shatavari or Sanspayein) is most commonly distributed species in tropical and subtropical regions of India. The folk use of Shatavari has been mentioned in traditional medicine system such as Unani & Siddh in folk and ayurvedic system British & Indian Pharmacopeias and is widely used shrub important for its sapogenin content which is the precursor of many pharmacologically active steroids. It is thought that almost all of its parts having pharmaceutical properties but roots stem and leaves are the most important parts which are used medicinally. The Shatavari is used as, "Rasayanas" to enhance the body resistance against infections and improve the immune system. It is widely used for the treatment of various ailments as it contains many different phytochemicals. The notable medicinal properties of Shatavari are antispasmodic, anti-oxidant, anti-diabetic, anti-allergic, anti-malarial, heap to protective, anti-neoplastic activities, enhance immune resposes, anti-arthritic, antiinflammatory, anti-periodic, Antiulcerogenic action, immune modulatory antistress, Anti-diarrhoeal, Antidepressant, anti-leprotic, anti-abortifacient activity, antibacterial, antipyretic and analgesic. The purpose of this review to evaluate and explore the information about chemical constituent and its pharmacological activities for further unexplored areas in which Asparagus can be proved to have potential to cure diseases.