original ) (raw )High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design
Isabel Barasoain Blasco
Scientific reports, 2018
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Synthesis, Cytotoxicity, Docking Study, and Tubulin Polymerization Inhibitory Activity of Novel 1-(3,4-Dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxanilides
Muh. S A B I R M.
Archiv der Pharmazie, 2014
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Design, Synthesis, and Biological Evaluation of Stable Colchicine Binding Site Tubulin Inhibitors as Potential Anticancer Agents
James Dalton
Journal of Medicinal Chemistry
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Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives
Jack A Tuszynski
Cells
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Design, synthesis, cytotoxic evaluation and tubulin inhibitory activity of 4-aryl-5-(3,4,5-trimethoxyphenyl)-2-alkylthio-1H-imidazole derivatives
Amir Assadieskandar
Bioorganic & Medicinal Chemistry, 2013
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Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity
Martine Pugnière
PLOS ONE, 2017
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Identification of Potential Antitubulin Agents with Anticancer Assets from a Series of Imidazo[1,2-a]quinoxaline Derivatives: In Silico and In Vitro Approaches
Kapil Kumar Goel
Molecules
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A Review on Docking Studies of Indole Moiety as Potent Inhibitor of Tubulin Polymerization
aditya dixit
European Chemical Bulletin, 2017
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Design and Biological Evaluation of Novel Tubulin Inhibitors as Antimitotic Agents Using a Pharmacophore Binding Model with Tubulin
Cheol Kyu Han
Journal of Medicinal Chemistry, 2006
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Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors
Monica Sardaru
Journal of Enzyme Inhibition and Medicinal Chemistry
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Design, Synthesis and Biological Evaluation of Imidazole-Substituted/Fused Aryl Derivatives Targeting Tubulin Polymerization as Anticancer Agents
Dr Satyendra Rajput
SynOpen, 2023
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Discovery of 4-Aryl-2-benzoyl-imidazoles as Tubulin Polymerization Inhibitor with Potent Antiproliferative Properties
James Dalton
Journal of Medicinal Chemistry, 2013
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A Screen for Kinetochore-Microtubule Interaction Inhibitors Identifies Novel Antitubulin Compounds
R. Gussio
PLoS ONE, 2010
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Synthesis, Cytotoxic Properties and Tubulin Polymerization Inhibitory Activity of Novel 2-Pyrazoline Derivatives
Susan Bane
Archiv der Pharmazie, 2012
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Structures of potent anticancer compounds bound to tubulin
Jorge Luis Almeida Torres
Protein science : a publication of the Protein Society, 2015
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Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents
James Dalton
Journal of Medicinal Chemistry, 2010
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Structure-based approaches for the design of benzimidazole-2-carbamate derivatives as tubulin polymerization inhibitors
Alicia Hernández-Campos
Chemical Biology & Drug Design, 2017
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Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity
Ashutosh Tripathi
Journal of Enzyme Inhibition and Medicinal Chemistry, 2009
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Novel Microtubule Polymerization Inhibitor with Potent Antiproliferative and Antitumor Activity
Cindy Peng
Cancer Research, 2009
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Arylthioindole Inhibitors of Tubulin Polymerization. 3. Biological Evaluation, Structure−Activity Relationships and Molecular Modeling Studies
Romano Silvestri
Journal of Medicinal Chemistry, 2007
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Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents
Jack A Tuszynski
Cells, 2018
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Identification and Validation of Novel Microtubule Suppressors with an Imidazopyridine Scaffold through Structure-Based Virtual Screening and Docking
Samia Ali
2021
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3D-QSAR and docking studies of benzoyl urea derivatives as tubulin-binding agents for antiproliferative activity
Aniket Shinde
Medicinal Chemistry Research, 2012
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Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells
Asmaa Kassem
Bioorganic & Medicinal Chemistry, 2018
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Looking for a new antitubercular pharmacophore site: synthesis and bioactivity of spiroheterocycles 2,3',4'-tri-subsituted-1,2-dihydro-4H,4'H-spiro[isoquinoline-3,5'-isoxazol]-4-ones
GHALI AL HOUARI
Arkivoc, 2007
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(Z)-1-Aryl-3-arylamino-2-propen-1-ones, Highly Active Stimulators of Tubulin Polymerization: Synthesis, Structure–Activity Relationship (SAR), Tubulin Polymerization, and Cell Growth Inhibition Studies
M V Ramana Reddy
Journal of Medicinal Chemistry, 2012
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