Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice (original) (raw)
The Role of Fibroblast Growth Factor 21 (FGF21) on Energy Balance, Glucose and Lipid Metabolism
Francisco Gómez-pérez
Current Diabetes Reviews, 2009
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Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo
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Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects
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Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice
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Metabolic actions of fibroblast growth factor 21
Francisco Gómez-pérez
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Fibroblast growth factor 21 is a metabolic regulator that plays a role in the adaptation to ketosis
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Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes
Anja Böhm
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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
Ffolliott Fisher
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Interplay between FGF21 and insulin action in the liver regulates metabolism
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Lu Cai
Molecular endocrinology (Baltimore, Md.), 2015
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Fibroblast Growth Factor 21 (Fgf21) Gene Expression Is Elevated in the Liver of Mice Fed a High-Carbohydrate Liquid Diet and Attenuated by a Lipid Emulsion but Is Not Upregulated in the Liver of Mice Fed a High-Fat Obesogenic Diet
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Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease
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Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance
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Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice
Ryan Sheldon
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FGF-21 as a novel metabolic regulator
George Sandusky
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Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
Joshua Thaler
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The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy
Martin Braddock
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Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice
Julie Serr
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Downstream Signaling Pathways in Mouse Adipose Tissues Following Acute In Vivo Administration of Fibroblast Growth Factor 21
An Chi
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Fibroblast Growth Factor 21 Limits Lipotoxicity by Promoting Hepatic Fatty Acid Activation in Mice on Methionine and Choline-Deficient Diets
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Serum FGF21 Levels Are Increased In Obesity and Are Independently Associated With the Metabolic Syndrome In Humans
Michal Karpisek
Diabetes, 2008
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Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice
Stephen Twigg
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FGF21 attenuates lipolysis in human adipocytes – A possible link to improved insulin sensitivity
A. Pettersson, Mikael Rydén
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Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity
Bruce Hultgren
Endocrinology, 2002
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The Role of Fibroblast Growth Factor 21 as an Endocrine Regulator of Lipid Metabolism: From Progression to Pathophysiology and Physiology
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Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance
Ralph DeFronzo
Diabetes Care, 2009
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MECHANISMS IN ENDOCRINOLOGY: Biological role, clinical significance, and therapeutic possibilities of the recently discovered metabolic hormone fibroblastic growth factor 21
sara romero
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Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes
Roberto A Calle
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Growth Hormone Induces Hepatic Production of Fibroblast Growth Factor 21 through a Mechanism Dependent on Lipolysis in Adipocytes
Ruby Hoo
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