[Trans fatty acids in the nutrition of children with neurological disorders] (original) (raw)
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Ácidos Grasos Trans en La Nutrición De Niños Con Trastornos Neurológicos
2013
Introduction: Trans-fatty acids are present in various foods, being the only source of the same in humans. Its presence in high concentrations is a risk factor for health, being involved in a series of events, cardiovascular, inflammatory, etc. Therefore, steps have been taken for its decrease in the diet. The aim is to determine serum and phospholipids of membranes in healthy children and neurological alterations. Material and methods: It has analyzed the fatty acids trans in 34 healthy children and 374 with various neurological pathologies. Serum and blood cells, making the lipid extraction, samples have been separation of the phospholipids of cells membranes, methylation of fatty acids, separation by gas chromatography and quantification using mass detector. The data have been processed statistically. Results: The distribution of trans fatty acids and their sum is not normally distributed, so its nonparemetric tests were used. The values are higher than in serum phospholipids and membrane with a weak but significant correlation. The tC18: 1 is in a double proportion in children with neurological disorders in healthy children, both in serum and membrane phospholipids, with significant differences. Discussion: The highest proportion of trans-fatty acids in the group of children with neurological disorders is caused no doubt by an increase in intake, due to less adequate food.
[Dietary trans fatty acids and its metabolic implications]
Gaceta médica de México
Fats are important nutrients in our diet, they have wide chemical properties that drive diverse metabolic effects. The trans fatty acids (TFA) are common compounds found in industrialized food, and recent research has shown they should be avoided due to their increased risk of cardiovascular disease (CVD). Some of the mechanisms involved include: reduction of c-HDL concentration, increase of low density lipoprotein, Lp (a), triglycerides; disturbance in prostaglandin balance and they may also promote insulin resistance. Obese subjects are prone to increased CVD risk associated with a state of chronic inflammation that can be worsened by TFA intake. The US population consumes approximately 5.3 g TFA per day (2.6% of their total energy intake and 7.4% of their fat energy). Recently, WHO recommendations suggest the intake of TFA should be lower than 1% of energy per day. Current fast food industry products have to decrease the amount of TFA content, and the experience from different co...
[Trans fatty acids: consumption effect on human health and regulation challenges]
Nutrición hospitalaria
Trans fatty acids (TFA) are stable to oxidative rancidity which allows them to have a long shelf-life: also they have an intermediate melting point between saturated and unsaturated fats. For these reasons they have been widely used by the food industry. However, in recent years a large number of epidemiological and clinical evidence has indicated that trans fats are a significant risk factor to suffer a cardiovascular event and appear to be involved in the process of inflammation, diabetes and cancer. The increase of 2% of the daily energy by TFA is associated with a 23% increase cardiovascular risk. Therefore, international organizations like WHO and PAHO recommend virtually eliminate them or make their consumption as low as possible, less than 1%. Considering this recommendation and the risk involved in its consumption, some countries in Europe and America have legislated to achieve a gradual reduction of these fats. Denmark is a country that has shown a reduced prevalence of car...
Ácidos Grasos Trans De La Dieta y Sus Implicaciones Metabólicas
Gac Méd …, 2010
Nacional de Enfermedades Crónicas indicó una prevalencia de obesidad en adultos de 21.5 %; para el 2000, la Encuesta Nacional de Salud encontró 24 % y; para 2006, la Encuesta de Salud y Nutrición más reciente en México (ENSANUT) encontró aproximadamente 30 % de obesidad en población mayor de 20 años (34.5 % en mujeres y 24.2 % en hombres). 2 Estos padecimientos (diabetes mellitus, enfermedades isquémicas del corazón y obesidad) se caracterizan por ser Palabras clave: Ácidos grasos trans, dieta, enfermedad cardiovascular, resistencia a la insulina, diabetes mellitus tipo 2, obesidad SUMMARY Fats are important nutrients in our diet, they have wide chemical properties that drive diverse metabolic effects. The trans fatty acids (TFA) are common compounds found in industrialized food, and recent research has shown they should be avoided due to their increased risk of cardiovascular disease (CVD). Some of the mechanisms involved include: reduction of c-HDL concentration, increase of low density lipoprotein, Lp (a), triglycerides; disturbance in prostaglandin balance and they may also promote insulin resistance. Obese subjects are prone to increased CVD risk associated with a state of chronic inflammation that can be worsened by TFA intake. The US population consumes approximately 5.3g TFA per day (2.6% of their total energy intake and 7.4% of their fat energy). Recently, WHO recommendations suggest the intake of TFA should be lower than 1% of energy per day. Current fast food industry products have to decrease the amount of TFA content, and the experience from different countries shows that the elimination of trans fatty acids is a cost effective and feasible public health intervention.
Nutricion hospitalaria, 2021
Long-chain polyunsaturated fatty acids (LC-PUFAs) are critical for infant growth and development, particularly arachidonic acid (ARA, C20:4n-6) and docosahexaenoic acid (DHA, C22:6n-3). ARA and DHA are components of cell membrane phospholipids and play an important role in cell division, differentiation, and signaling; and DHA is the n-3 fatty acid predominant in the developing brain and retina. During the third trimester of pregnancy, LC-PUFAs increase substantially in fetal circulation, and a "biomagnification" process in the fetal brain is observed. Moreover, LC-PUFAs are precursors of eicosanoids and metabolites, which modulate the intensity and duration of the immune response. LC-PUFA synthesis implies complex desaturation and elongation processes on their principal precursors, linoleic acid (LA) (18:3 n-6) (series n-6) and α-linolenic acid (LNA) (20:3 n-3) (series n-3), where fatty acid desaturases (FADS) and elongases (ELOVL) are competing. It is important to notice...
Nutrición del Niño con Enfermedades Neurológicas Prevalentes: An Update
Revista chilena de pediatría, 2010
In this paper, some neurological disorders are reviewed where nutritional management is relevant. These are cerebral palsy, epilepsy, autism and attention défi cit disorder (ADHD). Nutrition is affected in children with Cerebral Palsy due to the illness, diffi cult in ingesting foods due to sensory,motor and/or GI disorders, and specifi c nutritional défi cits secondary to insuffi cient intake. In epilepsy and ADHD, interaction with medications must be added. In autism there is additional controversy regarding nutritional management. Nutritional status will depend on the severity of the main disorder, time of evolution, adequate care. Nutritional vigilance by the multidisciplinbary treatment team. Good management contributes to improve the evolution of the illness, diminish medication adverse effect, prevent specifi c defi ciencies, development of excess disorders (as in obesity), and non nutritional complications (such as infections). (Key words: Nutrition, cerebral palsy, epilepsy, autism, attention défi cit disorder). Rev Chil Pediatr 2010; 81 (2): 103-113