Antigen-binding site protection during radiolabeling leads to a higher immunoreactive fraction (original) (raw)
The effect of circulating antigen and radiolabel stability on the biodistribution of an indium labelled antibody
Paul Boulos
British journal of cancer, 1991
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Labeling of monoclonal antibodies with radionuclides
Seetharama Acharya
Seminars in Nuclear Medicine, 1989
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Methods in molecular biology (Clifton, N.J.), 2014
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Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess
Frank Cuttitta
Journal of Immunological Methods, 1984
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Modification of antibody isoelectric point affects biodistribution of 111-indium-labeled antibody
Anthony Petrick
Nuclear Medicine and Biology, 1996
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Radiolabeling of Antibodies
William Eckelman
Cancer Research, 1980
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Methods for Radiolabelling of Monoclonal Antibodies
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Determination of the immunoreactive fraction of radiolabeled monoclonal antibodies directed against intracellular antigens
Hidde Haisma
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The binding parameters of radiolabelled monoclonal F (ab?)2 and Fab? fragments relative to immunoglobulin G in reactions with surface-bound antigens
Kjell Nustad
European Journal of Nuclear Medicine, 1992
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Rauni Norrlund, Lennart Johansson
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The labeling of high affinity sites of antibodies with 99mTc
Susan Heald
International Journal of Nuclear Medicine and Biology, 1985
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Effects of Radiolabeling Monoclonal Antibodies with a Residualizing Iodine Radiolabel on the Accretion of Radioisotope in Tumors1
Amartya Basu
2000
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The preparation of DTPA-coupled antibodies radiolabeled with metallic radionuclides: an improved method
a najafi
Journal of Immunological Methods, 1983
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Development of a stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer
Mark Hylarides
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989
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Comparative Cellular Catabolism and Retention of Astatine-, Bismuth-, and Lead-Radiolabeled Internalizing Monoclonal Antibody
William Eckelman
Journal of Nuclear Medicine, 2001
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Chelating polymer modified monoclonal antibodies for radioimmunodiagnostics and radioimmunotherapy
Ban-an Khaw
Journal of Controlled Release, 1993
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Development of a Model System to Evaluate Methods for Radiolabeling Monoclonal Antibodies
Robert Nicolotti
Journal of Nuclear Medicine, 1984
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Specific in vitro binding of radiolabeled antibodies to cell surface antigens: Interaction of antihuman thymocyte globulin with human target cells
William Butler
Journal of Immunological Methods, 1976
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Prevention of radiolysis of monoclonal antibody during labeling
Nhật Long Lê
Journal of Nuclear …, 1996
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In vivo measurement of the association constant of a radio-labelled monoclonal antibody in experimental immunotargeting
Kjell Nustad
British journal of cancer, 1992
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Iodination of monoclonal antibodies for diagnosis and radiotherapy using a convenient one vial method
Hidde Haisma
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1986
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Enhanced Target-Specific Accumulation of Radiolabeled Antibodies by Conjugating Arginine-Rich Peptides as Anchoring Molecules
Yasushi Arano
Bioconjugate Chemistry, 2010
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Assessment of the Radiochemical Design of Antibodies with a Metabolizable Linkage for Target-Selective Radioactivity Delivery
Yasushi Arano
Bioconjugate Chemistry, 1998
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Pharmacokinetics in Patients of an Anti-CarcinoembryonicAntigen Antibody Radiolabeled with Indium-Ill Using a Novel Diethylenetriamine Pentaacetic Acid Chelator1
anna rescigno
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Immunochemical aspects of monoclonal antibodies important for radiopharmaceutical development
Stanley Mills
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986
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Idiotypic-anti-idiotypic antibody interactions in experimental radioimmunotargeting
Anders Ullen
Clinical cancer research : an official journal of the American Association for Cancer Research, 1999
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Advantage of residualizing radiolabels for an internalizing antibody against the B-cell lymphoma antigen, CD22
Malik Juweid
Cancer Immunology, Immunotherapy, 1997
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Impact of the high tyrosine fraction in complementarity determining regions: measured and predicted effects of radioiodination on IgG immunoreactivity
Tuomo Nikula
Molecular Immunology, 1995
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Preparation of active iodinated specific antibodies
Daniel Louvard
FEBS Letters, 1975
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Blood clearance of radiolabeled antibody: enhancement by lactosamination and treatment with biotin-avidin or anti-mouse IgG antibodies
Vladimir Muzykantov
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1988
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A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides
Yasushi Arano
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994
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Influence of affinity of antibodies upon their detection by liquid phase radiobinding assay and solid phase enzyme linked immunosorbent assay. Demonstration using monoclonal antibodies raised against rDNA human proinsulin
D. Sondag, A. Rapaille
Diabetologia, 1991
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[Radiolabeled antibodies for cancer treatment]
Jacques Barbet
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A Putative Mechanism for the Non-Specific Uptake of Intact Radiolabelled Monoclonal Antibodies in the Testes and Prostate
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Acta Oncologica, 1996
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Chemical design of radiolabeled antibody fragments for low renal radioactivity levels
Yasushi Arano
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