A gate mechanism indicated in the selectivity filter of the potassium channel KscA (original) (raw)

Analysis of the Sequence KWKWK ... K in the KcsA Protein Channel using Molecular Dynamics Simulations

Christophe Ramseyer

2005

View PDFchevron_right

Exploring the origin of the ion selectivity of the KcsA potassium channel

Anton Burykin

Proteins-structure Function and Bioinformatics, 2003

View PDFchevron_right

Insight into the Mechanism of Inactivation and pH Sensitivity in Potassium Channels from Molecular Dynamics Simulations †

Phillip Stansfeld

Biochemistry, 2008

View PDFchevron_right

Potassium Channel, Ions, and Water: Simulation Studies Based on the High Resolution X-Ray Structure of KcsA

Carmen Domene

Biophysical Journal, 2003

View PDFchevron_right

Conformational Changes and Gating at the Selectivity Filter of Potassium Channels

Davide Branduardi

Journal of The American Chemical Society, 2008

View PDFchevron_right

Coordination Numbers of K+ and Na+ Ions Inside the Selectivity Filter of the KcsA Potassium Channel: Insights from First Principles Molecular Dynamics

Ursula Rothlisberger

Biophysical Journal, 2010

View PDFchevron_right

Importance of the Peptide Backbone Description in Modeling the Selectivity Filter in Potassium Channels

Turgut Bastug

Biophysical Journal, 2009

View PDFchevron_right

Molecular Dynamics Simulation Approaches to K Channels: Conformational Flexibility and Physiological Function

Carmen Domene

IEEE Transactions on Nanobioscience, 2005

View PDFchevron_right

Ion selectivity in potassium channels

Benoit Roux

View PDFchevron_right

The Protonation State of the Glu-71/Asp-80 Residues in the KcsA Potassium Channel: A First-Principles QM/MM Molecular Dynamics Study

Ursula Rothlisberger

Biophysical Journal, 2007

View PDFchevron_right

Dynamics, Energetics, and Selectivity of the Low-K+ KcsA Channel Structure

Carmen Domene

Journal of Molecular Biology, 2009

View PDFchevron_right

Role of water molecules in the KcsA protein channel by molecular dynamics calculations

Christophe Ramseyer

Physical Chemistry Chemical Physics, 2005

View PDFchevron_right

Selective exclusion and selective binding both contribute to ion selectivity in KcsA, a model potassium channel

Lourdes Renart

Journal of Biological Chemistry, 2017

View PDFchevron_right

Conformational plasticity in the KcsA potassium channel pore helix revealed by homo-FRET studies

Lourdes Renart

Scientific Reports, 2019

View PDFchevron_right

Molecular Dynamics of the Kcs A K+ Channel in a Bilayer Membrane

Benoit Roux

View PDFchevron_right

Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations

Benoit Roux

View PDFchevron_right

Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel

Benoit Roux

Journal of General Physiology, 2021

View PDFchevron_right

Molecular dynamics study of the KcsA channel at 2.0-Å resolution: stability and concerted motions within the pore

Christophe Ramseyer

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2004

View PDFchevron_right

Gating Motions in Voltage-Gated Potassium Channels Revealed by Coarse-Grained Molecular Dynamics Simulations

Werner Treptow

The Journal of Physical Chemistry B, 2008

View PDFchevron_right

Ion conduction and selectivity in K+ channels

Benoit Roux

View PDFchevron_right

Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

Benoit Roux

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016

View PDFchevron_right

K+ channel selectivity depends on kinetic as well as thermodynamic factors

Delphine Bichet

Proceedings of the National Academy of Sciences, 2006

View PDFchevron_right

A Gate in the Selectivity Filter of Potassium Channels

Benoit Roux

View PDFchevron_right

Comparative Study of the Energetics of Ion Permeation in Kv1.2 and KcsA Potassium Channels

Turgut Bastug

Biophysical Journal, 2011

View PDFchevron_right

Effects of Conducting and Blocking Ions on the Structure and Stability of the Potassium Channel KcsA

Maria Molina

Journal of Biological Chemistry, 2006

View PDFchevron_right

Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity

Delphine Bichet

Proceedings of the National Academy of Sciences, 2006

View PDFchevron_right

The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity

Declan Doyle

Science, 1998

View PDFchevron_right

Ion Selectivity of the KcsA Channel: A Perspective from Multi-Ion Free Energy Landscapes

Benoît Roux

Journal of Molecular Biology, 2010

View PDFchevron_right

The Open Gate Structure of the Membrane-Embedded KcsA Potassium Channel Viewed From the Cytoplasmic Side

Takehisa Dewa

Scientific Reports, 2013

View PDFchevron_right