Engineering Protein Dynamics of Ancestral Luciferase (original) (raw)
Engineering the protein dynamics of an ancestral luciferase
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Saman Hosseinkhani
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Stephanie Matthews
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1996
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Coelenterazine-v ligated to Ca2+-triggered coelenterazine-binding protein is a stable and efficient substrate of the red-shifted mutant of Renilla muelleri luciferase
Natalia Malikova
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Dorothee Kern
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Design of thermostable luciferases through arginine saturation in solvent-exposed loops
Saman Hosseinkhani
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Functional consequences of site-directed mutation of conserved histidyl residues of the bacterial luciferase .alpha. subunit
Xin Xing
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Peter Meinhold
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The Influence of Insertion of a Critical Residue (Arg356) in Structure and Bioluminescence Spectra of Firefly Luciferase
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Journal of Biological Chemistry, 2007
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Pathways and Mechanisms for Product Release in the Engineered Haloalkane Dehalogenases Explored Using Classical and Random Acceleration Molecular Dynamics Simulations
Jíří Damborský
Journal of Molecular Biology, 2009
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Dynamics and hydration explain failed functional transformation in dehalogenase design
Jíří Damborský
Nature Chemical Biology, 2014
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Probing the emitter site of Renilla luciferase using small organic molecules; an attempt to understand the molecular architecture of the emitter site
mahboobeh nazari
International Journal of Biological Macromolecules, 2016
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Novel methods for directed evolution of enzymes: quality, not quantity This review comes from a themed issue on Protein technologies and commercial enzymes Edited
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vy nguyen
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De novo design of luciferases using deep learning
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Biotechnological Advances in Luciferase Enzymes
Gary Sayler
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Directed evolution of enzymes for biocatalysis and the life sciences
Gavin P Williams
Cellular and Molecular Life Sciences, 2004
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Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics
ioanna zoi
Journal of the American Chemical Society, 2016
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Implication of a critical residue (Glu175) in structure and function of bacterial luciferase
Saman Hosseinkhani
FEBS Letters, 2005
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Are Time-Dependent Fluorescence Shifts at the Tunnel Mouth of Haloalkane Dehalogenase Enzymes Dependent on the Choice of the Chromophore?
Mariana Amaro
2013
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Molecular basis of thermostability enhancement of Renilla luciferase at higher temperatures by insertion of a disulfide bridge into the structure
Zahra Kahrani
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2017
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Protein dynamics in a family of laboratory evolved thermophilic enzymes
William Goddard
2003
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Illuminating the mechanism and allosteric behavior of NanoLuc luciferase
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