Drug metabolism in the paediatric population and in the elderly (original) (raw)

Hepatic Drug Metabolism and Aging

Chester Durnas

Clinical Pharmacokinetics, 1990

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Altered drug metabolism in hepatic and extrahepatic tissues in mice as a function of age

W. Al-turk

AGE, 1980

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Drug metabolism in older people—a key consideration in achieving optimal outcomes with medicines

Lisa Pont, Andrew McLachlan

The Journals …, 2011

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Age-related differences in hepatic drug clearance in children: Studies with lorazepam and antipyrine

Michael Christensen

Clinical Pharmacology and Therapeutics, 1991

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DRUG METABOLISM- CLINICAL PHARMACOLOGY

magendira mani vinayagam

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Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults

Pilar Tejada

Pharmaceutics, 2011

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Clinical implications of changes in hepatic drug metabolism in older people

Sarah Hilmer

Therapeutics and Clinical Risk Management, 2005

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Developmental Pharmacokinetics: Drug Disposition Relative to Age

Michelle Bestic

2014

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Determinants of Drug Metabolism in Early Neonatal Life

Gunnar Naulaers

Current Clinical Pharmacology, 2007

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Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions

Markku Pasanen

Clinical pharmacology and therapeutics, 1997

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Maturation of cytochrome P450 3A mediated drug metabolism: Towards individualized dosing in children

ibrahim ince

2013

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Drug Metabolism: Phase I and Phase II Metabolic Pathways

Maryam Farrukh

IntechOpen eBooks, 2024

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Evaluation of Child/Adult Pharmacokinetic Differences from a Database Derived from the Therapeutic Drug Literature

Dale Hattis, Rob Goble

Toxicological Sciences, 2002

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Introduction to the special issue on pharmacokinetics and pharmacodynamics in adolescents

Karen Hein

Journal of Adolescent Health, 1994

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Age-Related Pharmacokinetic and Pharmacodynamic Changes and Related Risk of Adverse Drug Reactions

A. Corsonello

Current Medicinal Chemistry, 2010

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DRUG METABOLISM IN MAN: PAST, PRESENT, AND FUTURE

Gopi Krishna

Annals of The New York Academy of Sciences, 1971

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Relationship between in vivo and in vitro drug metabolism in man

Jorma Ahokas

European Journal of Drug Metabolism and Pharmacokinetics, 1978

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A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study

Sylvie Pilote

British Journal of Clinical Pharmacology, 2004

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Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications

Stephen Jackson

British Journal of Clinical Pharmacology, 2003

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Handbook of Drug Metabolism

Patricia Kasar

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Clinical Trial Design and Alterations in Drug Disposition with Age

Michael Christensen

Therapeutic Innovation and Regulatory Science

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Pharmacokinetics and Pharmacodynamics in the Elderly

richard ogilvie

Geriatric Nephrology, 1986

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The ontogeny of drug metabolizing enzymes and transporters in the rat

Timothy C Coogan, Pieter Annaert, Loeckie Zwart, Luc Schaepdrijver

Reproductive Toxicology, 2008

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Polymorphisms of Drug-Metabolizing Enzymes in Healthy Nonagenarians and Centenarians: Difference at GSTT1 Locus

Sy Garte

Biochemical and Biophysical Research Communications, 2001

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Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis

Berit P Jensen

Pharmacogenomics, 2012

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Overview of Clinical Pharmacokinetics in Pediatrics: Possible Implications in Therapy

Herbert Obu

Biomedical & Pharmacology Journal, 2014

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Age-dependent modification of drug interference on the enzymatic activities of the rat brain

Fulvio Marzatico

Experimental Gerontology, 1980

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Advances in drug metabolism and pharmacogenetics research in Australia

Andrew Somogyi

Pharmacological Research, 2017

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Relevance of induction of human drug-metabolizing enzymes: pharmacological and toxicological implications

Munir Pirmohamed

British Journal of Clinical Pharmacology, 2003

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Comparison of microsomal drug-metabolizing enzymes in 14 rat inbred strains

Leo Nieuwenhuis

Biochemical Pharmacology

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Nutrition and drug disposition

Suraj Gupte

The Indian Journal of Pediatrics, 1986

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