PREVALENCE AND SEVERITY OF DEPRESSION AMONG PEOPLE LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS IN YENAGOA, SOUTHERN NIGERIA (original) (raw)
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Nigerian Journal of Clinical Practice, 2013
Background: Depression is a common co-morbidity among persons living with human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS) (PLWHAs). It is associated with poor treatment adherence and higher mortality rates. Few reports have, however, emanated from developing countries where socioeconomic factors may confound this association. Materials and Methods: We conducted a cross-sectional comparative study of PLWHAs and apparently healthy staff of three LGA's. The depression module of the Schedule for the Clinical Assessment in Neuropsychiatry (SCAN) and the Beck Depression Inventory (BDI) was used to diagnose depression and depression symptom severity, respectively. Results: Depression was commonly co-morbid among individuals with HIV/AIDS. It was five times more common in PLWHAs than in apparently healthy populations (29.3% vs. 7.3%, OR: 5.25, 95% CI: 2.50-11.76). A similar trend was observed for depression symptom severity. Among PLWHAs, depression was significantly more likely among females (OR: 7.91, 95% CI: 1.83-71.00, P < 0.01), those unemployed (OR: 2.94, 95% CI: 0.18-1.82, P < 0.04), and with an illness duration >3 years (OR: 7.90, P < 0.0001). Having at least one child (OR: 2.79, 95% CI: 1.25-6.16, P < 0.001) and living with others (OR: 4.71, 95% CI: 1.51-15.52, P < 0.003) significantly reduced depression risk. Conclusion: Depression was commonly co-morbid among PLWHAs studied. Clinicians should be aware of risk factors for depression among PLWHAs in order to improve treatment outcomes.
Family Medicine & Primary Care Review, 2021
Background. Mental health disorders have received little attention amongst people living with HIV/AIDS (PLWHA). Depression is the most common psychiatric consequence of HIV/AIDS diagnosis. Its prevalence is higher among PLWHA than the general population. Objectives. To determine the prevalence of depression, to identify its associated factors and, lastly, to determine its association with treatment outcome measures among PLWHA on antiretroviral therapy (ART) aged ≥ 18 years receiving care at the HIV clinic of General Hospital, Lagos. Material and methods. A cross-sectional study was conducted using the systematic random sampling method to select participants over a period of 14 weeks. An interviewer-administered questionnaire was designed to capture socio-demographic, behavioural, psychosocial, HIV and health-related information, as well as the clinical data of the participants. The Patient Health Questionnaire (PHQ-9) was used to assess depression. The relationships between depression and other participants' characteristics were tested with Pearson's chi-squared (χ 2) test. Logistic regression analysis was used to minimise confounding, and the level of statistical significance was set as a p-value of ≤ 0.05. Results. The total of 279 respondents, with a mean age of 43.1 ± 10.3 years, were predominantly females (67.7%). The prevalence of depression among the participants was 24%. Factors such as occupation (p = 0.041; 95% CI, 0.43 to 3.63), alcohol intake (p = 0.036; 95% CI, 0.62 to 3.82), cohabitation (p = 0.025; 95% CI, 1.43 to 3.82), stigmatisation (p = 0.008; 95% CI, 0.92 to 3.70) and personal history of depression (p < 0.001; 95% CI: 1.75 to 6.38) showed statistically significant relationships with depression. Conclusions. The burden of depression is high among PLWHA. Identifying and unravelling factors associated with depression among PLWHA and advocacy against stigmatisation will play a significant role in reducing this burden.
2019
Clinical depression has been associated with various chronic disease conditions. The chronic course of HIV, fostered by the use of antiretroviral therapy in infected patients, puts them at risk of developing clinical depression which unfortunately, is often underdiagnosed and therefore undertreated. The study estimated the prevalence of depression and associated factors amongst adult patients receiving antiretroviral therapy in a clinic in Jos, using the PHQ-9 questionnaire. Three hundred and fourteen patients with a mean age of 45 ± 10 years were enrolled in a descriptive cross-sectional study. There were 63 males and 251 females, with mean known duration of HIV infection of 11 ± 4 years. Depression was found to be common in the group. Thirty one percent of the patients had depression, and of these, 83 (85%) had mild depression while 12 (12%) had moderate depression and 3 (3%) had moderately severe depression. The factors associated with depression in these patients were analysed u...
Background: Depression is a common mental disorder (CMD) with significant contributions to the burden of disease. It can lead to high social, economic and individual costs because it accounts for onethird of the days missed at work and a fifth of all primary health-care appointment. Objective: We aimed to explore the prevalence of and risk factors for depressive symptoms among people living with HIV/AIDS (PLWHA) receiving antiretroviral treatment (ART) in Kebbi State, Nigeria. Method: A cross-sectional study evaluating adult PLWHA receiving ART in three designated clinical hospitals was conducted. The validated Beck Depression Inventory (BDI) was used to assess depressive symptoms, ineligible participants. Result: Multinomial regression analysis was used to explore the risk factors for depressive symptoms. 348 participants were finally included in all analyses. 40.3% were found to have depressive symptoms with 13.7% having mild depressive symptoms and 26.6% having moderate to severe depressive symptoms. Conclusion: The results of multinomial regression analysis suggested that being married or living with a partner, recent experience of ART-related side effects, and/or history of HCV infection were positively associated with mild depressive symptoms, while increasing age was positively associated with moderate to severe depressive symptoms.
2014
Objectives: Depressive disorders are a significant public health issue. They are prevalent, disabling, and often chronic, with a high economic burden to the society. Depressive illness is the most common psychiatric disorder in HIV/AIDS with prevalence 2 to 4 times higher than the general population. It's still questionable whether HIV related depression is clinically different from sero-positive patients without depression. Studies comparing the clinical features of depressed and non-depressed People Living with HIV/AIDs are limited, hence the need for this study. Methods: This was a hospital based, cross sectional, descriptive study of three hundred adult HIV/AIDS patients attending the HIV clinic of Kwara State specialist hospital, Sobi, Ilorin. The PHQ-9 was administered to the respondents to screen for depression. A pre-tested PHQ-9 questionnaire was used to collect data. Subject who scored one and more were assessed clinically for depression. The three keys of social determinants of depression (SDS) were assessed and the association with depression sought. Results: One hundred and seventy (56.7%) satisfied the criteria for a depressive disorder using the PHQ-9 score. Compared to non-depressed sero-positive patients, depressed HIV patients were more likely to be female, single, unemployed, with below average year of schooling, low social economic status, low social cohesion and more stressful life events. They are more prone to hopelessness, thought of taking life and plan to commit suicide. Conclusion: These findings, show that the clinical and associated features of depression differ between depressed and non-depressed sero-positive subjects, thus requiring different management.
Journal of Public Health in Africa, 2014
Clinical depression is a highly debilitating illness, which is often under-diagnosed and negatively impacts on the quality of life of its sufferers. When it co-exists with other medical conditions, its effect is even more incapacitating. Undiagnosed depression in the context of HIV infection leads to accelerated decline in CD4+ cell counts with concomitant increase in the viral load and poor adherence to the antiretroviral medications which lead to viral mutation and the evolution of resistant strains. This study examined the prevalence of depression, its correlates and the frequency of the diagnosis of the condition among HIV+ subjects on highly active antiretroviral therapy (HAART) by the internists and general physicians at the University of Maiduguri Teaching Hospital in Northeastern Nigeria.
RELATIONSHIP BETWEEN DEPRESSION AND QUALITY OF LIFE IN PERSONS WITH HIV INFECTION IN NIGERIA
Objective: Despite the fact that two-thirds of all the people with HIV live in sub-Saharan Africa, little is known about the emotional state and quality of life (QOL) of subjects with HIV in this region. The objective of this study was to evaluate the association between clinical depression and quality of life in a group of HIV sero-positive subjects in Nigeria. Methods: Subjects with HIV infection (n = 87) completed a questionnaire detailing sociodemographic and HIV related variables. The subjects were assessed for the diagnosis of depression using the Mini International Neuropsychiatric Interview (MINI) 43
2019
Background: Depression is one of the most frequently observed psychiatric disorder among patients with HIV/AIDS and it has been associated with increased risky behaviors, noncompliance to anti-retroviral treatment, and higher risk for co-morbid survival. Aim: This study was conducted to determine the prevalence and pattern of depression among HIV positive patients on treatment at the ART clinic of UDUTH, Sokoto, Nigeria. Materials and Methods: This was a cross-sectional study among 419 patients (selected by systematic sampling technique) attending the ART clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. A structured interviewer-administered questionnaire was used to collect data on the research variables. Data were analyzed using IBM SPSS version 20 statistical computer software package. Results: Two hundred and twenty-seven (54.2%) of the 419 participants were identified as having depression, with 179 (42.7%) having mild depression, 46 (11.0%) having modera...
Neuropsychiatric Disease and Treatment
Background: Depression is one of the most common psychiatric disorders with the prevalence rate ranging from 5% to 10% in the general population and about 60% in people living with human immunodeficiency virus (PLHIV). It has been reported to be more common among women living with HIV. In HIV patients, depression can have negative impacts on their quality of life. Objective: This study was aimed at identifying the prevalence of depressive symptoms and associated factors among PLHIV attending the antiretroviral therapy clinic at Fitche Zonal Hospital. Methods: It was a cross-sectional study conducted among PLHIV in Fitche Zonal Hospital from February 15 to March 15, 2012. Center for Epidemiologic Studies Depression tool was used to collect data from 390 respondents. Both the bivariate and multivariable logistic regression analyses were carried out and variables with P,0.25 in the bivariate logistic regression analysis were entered into multivariable logistic regression analysis and statistical significance was declared at P,0.05. Results: Of the total 390 respondents included in the analysis, the prevalence of depressive symptoms was 76.7%, ranging from mild to moderate (33.6%) to major (43.1%), and the highest proportion was observed among individuals with food insecurity accounting for 287 (79.3%). Food insecurity (adjusted odds ratio [AOR] =3.832 [1.575-9.322]), non-ownership of livestock (AOR =2.17 [1.157-4.104]), and opportunistic infections (AOR =5.20 [1.342-20.156]) were significantly associated with depressive symptoms. Conclusion and recommendations: Depressive symptoms were prevalent in PLHIV. Social disparities were important factors of depressive symptoms. Integration of mental health care services with HIV/acquired immune deficiency syndrome-related health care services at all health care levels was necessary. It was recommended that government and non-government organizations should provide assistance to the PLHIV to encourage their involvement in income-generating activities.