Quality of Life of People with Multiple Sclerosis:Clinical and Psychosocial Determinants (original) (raw)
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Quality of life among persons suffering from multiple sclerosis
2019
Objective: To examine the quality of life of people affected by multiple sclerosis and to determine whether there is a difference in the quality of life according to sex, age, education, employment status, marital status and overall duration of the disease. Materials and methods: The study included 81 patients with MS (32 men and 49 women) over 18 years of age. The survey instrument used was a standardized MSQoL-54 specific questionnaire for measuring the quality of life of patients with multiple sclerosis. Results: Men rated their health significantly better than women in dimensions of energy/vitality (p = 0.028) and dimensions of pain (p = 0,018), while women rated significantly better in the dimension health perceptions (p = 0.025). The dimensions of health that described physical health (p < 0.001), pain (p = 0.047), sexual functioning (p = 0.036), social functioning (p = 0.047) and overall quality of life (p = 0.012) were significantly worse rated by the oldest respondents. Ratings of physical health (p < 0.001) and overall quality of life scale (p = 0.017) were significantly the lowest in subjects older than 55 years. According to the level of education, significant differences were present only in dimensions to energy/vitality (p = 0.004) and health distress (p = 0.015). As regards to employment status, dimensions that described physical health (p = 0.001), health perception (p = 0.001), social function (p = 0.002), health distress (p = 0.010), overall quality of life (p = 0.009), physical health composite (p = 0.001), mental health composite (p = 0.007) and overall quality scale of quality of life (p = 0.003) were the significantly worse rated respondents. According to disease duration the lowest rating to quality of physical health was given by respondents suffering from MS for 21 years and longer (p = 0.007). Conclusion: Research shows that multiple sclerosis impairs the quality of life of patients. The use of instruments designed to measure multiple sclerosis patients' quality of life, based on subjective perceptions of quality of life, facilitates the implementation of targeted interventions and measures that improve the quality of life.
Influence of the Profile of the Person with Multiple Sclerosis in the Quality of Life
Arq. Neuro-Psiquiatr., 2015
Multiple Sclerosis (MS) is a chronic neurological disease, it reaches mainly young adults. A modified immunological response creates a demyelination in Central Nervous System (CNS) resulting in an ample variety of signals and neurological symptoms. The great disability, functional and mental impairment influences directly in the social life and wellbeing of the MS patients meaning a great impact in quality of life. The aim of this study was evaluate the influence of profile in quality of life in patients with MS. Thirty five patients from Sao Paulo and surroundings were recruited, the profile was evaluated by a structuralized questionnaire, the quality of life by Functional Assessment of Multiple Sclerosis Quality of Life. Social and economic profile demonstrated little influence in quality of life which was more affected by functional impairment and severity of the symptoms.
Contributing Factors to the Quality of Life in Multiple Sclerosis
Medical Archives, 2020
Introduction: Multiple sclerosis (MS) is a chronic, inflammatory, (auto) immune disease of the central nervous system (CNS). Quality of life (QoL) refers to the perception of an individual's life in the context of the system of culture and values in which they live. Aim: The aim of the study was to determine the distribution of cognitive disorders in people with MS. Methods: The prospective study included 135 participants with MS and 50 healthy participants. Participants were divided into three groups: the first group consisted of 85 participants where the disease lasted longer than one year, the second group consisted of 50 participants with newly diagnosed MS, the third group consisted of 50 healthy participants. The instruments of clinical assessment were: Extended Disability Score in Multiple Sclerosis Patients, Mini Mental Status, Beck Depression Scale, and Quality of Life Scale (SF-36, Contemporary Health Survey). Results: The quality of life related to health is impaired in the physical, mental dimension and overall quality of life. In the first group of participants, 62% had mild depression, and in the second group 38% of participants, while more severe forms were recorded in 16% of participants in both groups. As depression increases, the quality of life decreases in all measured dimensions, which would mean that depression negatively affects the quality of life. The results of all dimensions as well as the overall quality of life score are worse with the increase in the degree of clinical disability, for both groups of study patients. Conclusion: Quality of life is impaired in MS patients, and a higher degree of clinical disability and an increase in depressive disorder are predictors of deteriorating quality of life in MS patients.
2020
Background: Multiple Sclerosis (MS) is one of the most important diseases due to its adverse clinical, social and economic consequences for affected people. Objectives: This study tried to assess the quality of life of the patients suffering from Multiple Sclerosis in East Azerbaijan. Methods: This cross-sectional study used the Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaire for interviewing 300 randomly selected MS patients in East Azarbaijan province, Iran. The independent T-test, ANOVA and Tukey post hoc test were used to examine the relationship between demographic variables and quality of life, and all analyses were performed using SPSS19. Results: The quality of life score among the MS patients is 48.22. The "life satisfaction" is the best and "physical role limitation" is the worst quality of life aspect. There were significant relationships between marital status, education level, employment status, age of symptoms onset and years of illness with quality of life (P<0.05). Conclusion: The quality of life of the MS patients in East Azarbaijan province is lower than other parts of Iran and much lower than OECD countries. Background Multiple Sclerosis (MS) is a complicated chronic and inflammatory disorder of the Central Nervous System (CNS) with the main characteristic of demyelination and loss of neuronal axons which, consequently contributes to malfunction and disabilities (1-3). Epidemiological studies have shown that the prevalence of MS is about 150/100000 people (4, 5). Worldwide about 1.3 million are suffering from MS (6). MS generally affects young adults causing long-lasting disabilities during the productive age of the patients imposing many clinical and socioeconomic burdens (2, 7). The cause of MS is still unclear and the prognosis of its improvement is very difficult. Although MS does not affect life expectancy, 50% of the cases, after 10 years of the diagnosis, face main problems of movement and need others' support (8). Most of the patients with major disabilities need informal and specialized care services by their families (9). MS leaves significant negative effects on the Quality of Life (QOL) among patients. For instance, in Switzerland it causes a loss of 0.3 in the Quality
A review about the impact of multiple sclerosis on health-related quality of life
Disability and Rehabilitation, 2003
Purpose: There is increasing recognition that the global wellbeing of patients with chronic neurological disease is an important outcome in research and clinical practice alike. Many studies involving individuals with multiple sclerosis have demonstrated that the overall wellbeing is not a simple manifestation of impairment or disability. The strongest correlations with health-related quality of life appear to be patient rated emotional adjustment to illness and patient rated handicap. In recent years, health-related quality of life questionnaires that measure the physical, social, emotional, and occupational impact of illness have been developed and validated in populations with MS. Most questionnaires are now available in a range of languages. This development is likely to lead to increasing recognition of neuropsychiatric complications of MS in clinical practice and better quantification of treatment responses in clinical trials. Conclusion: Further work is required to decide which scale is most suited to which purpose. Assessment of multiple sclerosis-specific health-related quality of life should be included in future clinical trials to provide a complete picture of patients' health status.
Assessing the Quality of Life in Individuals with Multiple Sclerosis
Arhivi na javnoto zdravje, 2023
Оваа статија е со отворен пристап дистрибуирана под условите на нелокализирана лиценца, која овозможува неограничена употреба, дистрибуција и репродукција на било кој медиум, доколку се цитираат оригиналниот(ите) автор(и) и изворот. Конкурентски интереси: Авторот изјавува дека нема конкурентски интереси.
Multiple Sclerosis, 2007
KV, et al. Deterioration in health-related quality of life of persons with MS: the possible warning signs. Mult Scler. 2007;13:1038-1045. Phillips LJ, Stuifbergen A. Influence of positive experiences on depression and quality of life in persons with MS. J Holist Nurs. 2008;26:41-48. Rossen EK. Commentary [on the study of Phillips and Stuifbergen]. J Holist Nurs. 2008;26:49. Buhse M. Assessment of caregiver burden in families with MS.
Social Characteristics and Quality of Life of Portuguese Multiple Sclerosis Patients
Neurology and Therapy, 2013
Introduction: Few studies have analyzed the importance of socio-demographic variables on the perception of health-related quality of life (HRQoL) in patients with multiple sclerosis (MS). Methods: The sample was composed of 150 patients with MS. Statistical analysis was performed using Mann-Whitney U and Kruskal-Wallis H non-parametric tests comparing sociodemographic items with HRQoL. Results: We found statistically significant differences between age, education levels, employment status, disability and all dimensions of HRQoL. Discussion: This study contributes to a more systematic knowledge about the relationship between social characteristics and HRQoL, which is important to improve the planning of health care in MS patients. Conclusion: We found that younger patients, those with higher education level, those who were employed, and with lower disease progression and lower disability, had better HRQoL.
Quality of life in patients with multiple sclerosis
2013
Multiple sclerosis is a chronic, immune-mediated disease of the central nervous system that typically strikes young adults. It is often associated with a wide range of functional deficits and progressive disability. Common symptoms of multiple sclerosis include vision problems, spasticity, weakness, ataxia, bladder and bowel dysfunctions, fatigue, pain syndromes, tremors, vertigo, cognitive impairment, and mood disorders. Multiple sclerosis has a major negative impact on patient health-related quality of life (HRQoL). Quality of life (QoL) is a multidimensional construct composed of functional, physical, emotional, social and spiritual well-being. Researches have reported that individuals with multiple sclerosis have lower QoL than non-diseased and diseased populations. The inclusion of HRQoL questionnaires in the patient follow-up is a relevant issue to optimize treatment, facilitate treatment decisions and improve adherence, as well as to reduce the inconveniences derived from med...
Quality of life in patients with multiple sclerosis in Republic of Srpska
Acta Clinica Croatica, 2013
Multiple sclerosis is a chronic, immune-mediated disease of the central nervous system that typically strikes young adults. It is often associated with a wide range of functional deficits and progressive disability. Common symptoms of multiple sclerosis include vision problems, spasticity, weakness, ataxia, bladder and bowel dysfunctions, fatigue, pain syndromes, tremors, vertigo, cognitive impairment, and mood disorders. Multiple sclerosis has a major negative impact on patient health-related quality of life (HRQoL). Quality of life (QoL) is a multidimensional construct composed of functional, physical, emotional, social and spiritual well-being. Researches have reported that individuals with multiple sclerosis have lower QoL than non-diseased and diseased populations. The inclusion of HRQoL questionnaires in the patient follow-up is a relevant issue to optimize treatment, facilitate treatment decisions and improve adherence, as well as to reduce the inconveniences derived from medication such as side effects.