Robust interferon-α and IL-12 responses by dendritic cells are related to efficient CD4+ T-cell recovery in HIV patients on ART (original) (raw)

Impaired restoration of plasmacytoid dendritic cells in HIV-1-infected patients with poor CD4 T cell reconstitution is associated with decrease in capacity to produce IFN-α but not proinflammatory cytokines

Alaka Deshpande, Naresh Sachdeva

2008

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Impaired restoration of plasmacytoid dendritic cells in HIV-1-infected patients with poor CD4 T cell reconstitution is associated with decrease in capacity to produce IFN-alpha but not proinflammatory cytokines

Naresh Sachdeva

Journal of immunology (Baltimore, Md. : 1950), 2008

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The number and function of circulating dendritic cells may limit effector memory CD4+ T-cell responses in HIV patients responding to antiretroviral therapy

Patricia Price

Clinical Immunology, 2008

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Persistent Decreases in Blood Plasmacytoid Dendritic Cell Number and Function Despite Effective Highly Active Antiretroviral Therapy and Increased Blood Myeloid Dendritic Cells in HIV-Infected Individuals

Jay Kostman

The Journal of Immunology, 2002

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Early Plasmacytoid Dendritic Cell Changes Predict Plasma HIV Load Rebound during Primary Infection

Anne Hosmalin

The Journal of Infectious Diseases, 2004

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Decreased Stimulation of CD4+ T Cell Proliferation and IL-2 Production by Highly Enriched Populations of HIV-Infected Dendritic Cells

Mark Connors

The Journal of Immunology, 2003

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Increased proportions of dendritic cells and recovery of IFNγ responses in HIV/HCV co-infected patients receiving ART

Henny Saraswati

Human immunology, 2015

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Defective Dendritic Cell Function in HIV-Infected Patients Receiving Effective Highly Active Antiretroviral Therapy: Neutralization of IL-10 Production and Depletion of CD4+CD25+ T Cells Restore High Levels of HIV-Specific CD4+ T Cell Responses Induced by Dendritic Cells Generated in the Presence...

Cédric Carbonneil

The Journal of Immunology, 2004

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Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection

Joann Kuruc

AIDS research and human retroviruses, 2017

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Plasmacytoid Dendritic Cells Count in Antiretroviral-Treated Patients is Predictive of HIV Load Control Independent of CD4+ T-Cell Count

Miriam Lichtner

Current HIV Research, 2008

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Persistent Abnormalities in Peripheral Blood Dendritic Cells and Monocytes from HIV-1-Positive Patients After 1 Year of Antiretroviral Therapy

Maria Goreti Pinto Sá Almeida

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2006

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Immunosenescent CD57+CD4+ T-cells Accumulate and Contribute to Interferon-γ Responses in HIV Patients Responding Stably to ART

Patricia Price

Disease Markers, 2011

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Major Depletion of Plasmacytoid Dendritic Cells in HIV-2 Infection, an Attenuated Form of HIV Disease

Rita Tendeiro

PLoS Pathogens, 2009

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Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand

Jay Kostman

Journal of virology, 2010

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Blood Myeloid Dendritic Cells and slanDC in Antiretroviral Therapy- Suppressed HIV-Infected Patients

Miriam Lichtner

Current HIV Research, 2016

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Evidence of dysregulation of dendritic cells in primary HIV infection

david margolis

2010

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High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

Harriet Mayanja-kizza

BMC Infectious Diseases, 2011

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Decreased Interferon-α Production in HIV-Infected Patients Correlates with Numerical and Functional Deficiencies in Circulating Type 2 Dendritic Cell Precursors

Thomas Denny

Clinical Immunology, 2001

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Exceptional T CD4 + Recovery Post-antiretroviral Is Linked to a Lower HIV Reservoir with a Specific Immune Differentiation Pattern

Monica Viveros Rogel

AIDS Research of Human Retroviruses, 2022

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Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection

Gabriel Alejandro Lopz Ortiz

PloS one, 2013

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Characteristics of Plasmacytoid Dendritic Cell and CD4+ T Cell in HIV Elite Controllers

Jean-philippe Herbeuval

Clinical and Developmental Immunology, 2012

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Interleukin-15 production by monocyte-derived dendritic cells and T cell proliferation in HIV-infected patients with discordant response to highly active antiretroviral therapy

Loredana Sarmati

Clinical and Experimental Immunology, 2004

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Low antigen-specific CD4 T-cell immune responses despite normal absolute CD4 counts after long-term antiretroviral therapy an African cohort

Rose Nabatanzi, Isaac Ssinabulya

Immunology Letters, 2014

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Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection

J. Pacanowski

Blood, 2001

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Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

Núria Pérez

Clinical Infectious Diseases, 2010

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Absolute CD4+ T cell count overstate immune recovery assessed by CD4+/CD8+ ratio in HIV-infected patients on treatment

Luis López-cortés

PLOS ONE

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