ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study (original) (raw)

Annals of the rheumatic diseases, 2015

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

Masayuki Sakiyama, Asahi Hishida

Scientific Reports, 2013

Association of Functional Polymorphism rs2231142 (Q141K) in the ABCG2 Gene With Serum Uric Acid and Gout in 4 US Populations

Saroja Voruganti

American Journal of Epidemiology, 2013

Pleiotropic effect of ABCG2 in gout: involvement in serum urate levels and progression from hyperuricemia to gout

Anne-Kathrin Tausche

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people

Anna Kottgen

Rheumatology, 2010

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

abbas dehghan

Lancet, 2008

Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia

Balazs Sarkadi

Clinical and Experimental Medicine

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

Annals of the Rheumatic Diseases

Interaction of the p.Q141K Variant of the ABCG2 Gene with Clinical Data and Cytokine Levels in Primary Hyperuricemia and Gout

Journal of Clinical Medicine

Multiple common and rare variants of ABCG2 cause gout

RMD Open

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk FactorsClinical Perspective

Lenore Launer

2010

Polymorphisms of ABCG2 and SLC22A12 Genes Associated with Gout Risk in Vietnamese Population

Nguyen Thang

Medicina, 2019

Associations and Combinations of Metabolic Parameters and ABCG2 rs2231142 Variant in Thai Men with Gout

Kitsarawut Khuancharee

Journal of Health Science and Medical Research (JHSMR), 2023

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors

Thor Aspelund

Circulation: Cardiovascular Genetics, 2010

The genetics of hyperuricaemia and gout

Anthony Reginato

Nature reviews. Rheumatology, 2012

Faculty of 1000 evaluation for Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

Richard Naftalin

F1000 - Post-publication peer review of the biomedical literature, 2009

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele

Adebowale Adeyemo

Human Molecular Genetics, 2011

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

Anna Kottgen

Proceedings of the National Academy of Sciences, 2009

Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease

Elke Schaeffner

Scientific reports, 2018

Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2

Arthritis Research & Therapy

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Annals of the rheumatic diseases, 2016

Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk

Scientific reports, 2017

A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not M(a)over-barori, case and control sample sets

Peter Gow

2010

Differential gene expression of ABCG2, SLC22A12, IL-1β and ALPK1 in peripheral blood leukocytes of primary gout patients, was associated to hiperuricemia and their comorbidities. A case control study

Laura Sánchez-chapul

2021

AB0096 ANALYSIS of the Gene Expression of URAT-1, ABCG2, GLUT-9, OCT3, IL1Β, TLR4 and ALPK1 in Mononuclear Cells of Patients with Inter-Critical Gout

Laura Sánchez Chapul

Abstracts Accepted for Publication, 2019

Common variant of PDZ domain containing 1 (PDZK1) gene is associated with gout susceptibility: A replication study and meta-analysis in Japanese population

Drug Metabolism and Pharmacokinetics, 2016

Inflammasome genes polymorphisms and susceptibility to gout. Is there a link?

Esteban Cruz Arenas

Revista de investigaci�n Cl�nica, 2022

Common variant of PDZK1, adaptor protein gene of urate transporters, is not associated with gout

Asahi Hishida

The Journal of rheumatology, 2014

Gout and Type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences

Chung-Jen Chen

Rheumatology, 2012

Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility

Human cell, 2014

Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout

Richard Day

Arthritis research & therapy, 2015

Molecular analysis of the SLC22A12 (URAT1) gene in patients with primary gout

Ruben Burgos-Vargas

Rheumatology, 2006