Orthokeratinized Odontogenic Cyst: Case Report (original) (raw)
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Orthokeratinized Odontogenic Cyst: A Case Report- A Milder Variant of OKC or an Independent Entity
https://www.ijhsr.org/IJHSR\_Vol.7\_Issue.9\_Sep2017/IJHSR\_Abstract.049.html, 2017
Orthokeratinized odontogenic cyst (OOC) is a relatively uncommon developmental cyst, thought to be arising from the cell rests of the dental lamina. Orthokeratinized odontogenic cyst (OOC) was first described by Schultz in 1927 and in 1945 Philipsen considered it to be a variant of Odontogenic keratocyst (OKC). OOC exhibits distinctive clinical, pathologic, and behavioral features that varied substantially from KCOT and hence now it is considered as a separate entity. We present a rare case of OOC occurring in a female patient which was attached to the lateral aspect of the root apex of the impacted third molar giving a false gross and radiographic appearance of lateral variant of dentigerous cyst.. The clinical, radiological, and histopathological features of this cyst and its surgical management are discussed.
Orthokeratinized odontogenic cyst : case report of two cases with review of literature
2017
An orthokeratinized odontogenic cyst (OOC) is a rare developmental jaw cyst, that has been considered as a variant of the keratocystic odontogenic tumour (KCOT), which was irst described in 1927 by Schultz. We, report two cases of OOC along with review of literature. Of the two cases, the irst one was noted in a 31 year old female, while the second one was seen in 48 year old male, both affecting the right posterior region of the mandible. Since, OOC has a less aggressive nature & no propensity to recur a conservative management with complete enucleation of the cystic lesion seems to be the treatment of choice compared to KCOT, where the ideal treatment involves more radical approach, through peripheral osteotomy, chemical curettage or block resection. Hence, now it has become essential to identify OOC as a distinct entity, as it is an odontogenic cyst with varied biological behaviour.
Orthokeratinized Odontogenic Cyst
Journal of Contemporary Dentistry, 2012
Orthokeratinized odontogenic cyst (OOC) is a developmental cyst of odontogenic origin and was initially defined as the uncommon orthokeratinized variant of odontogenic keratocyst (OKC). However, recently World Health Organization has designated OOC as a distinct clinicopathologic entity as it has peculiar clinicopathologic aspects when compared to other developmental odontogenic cysts, especially OKCs. The orthokeratinized odontogenic cyst is histologically characterized by a thin, uniform, epithelial lining with orthokeratinization and a subjacent prominent granular cell layer. The purpose of the article is to present a case of OOC arising in the anterior mandible, an unusual site for the lesion and also highlights the importance of distinguishing it from the more commonly occurring keratocystic odontogenic tumor (KCOT).
Orthokeratinized odontogenic cyst arising from dentigerous cyst: A case report
2018
Tel: +98-21-88351163 Fax: +98-21-42794142 Email: ghati1374@Yahoo.com One specific type of keratinized odontogenic cysts is orthokeratinized odontogenic cyst which is different from odontogenic keratocyst in clinical and pathological features completely. Also orthokeratinized odontogenic cyst can mimic typical characteristic clinicopathologic features of some other developmental odontogenic lesions such as dentigerous cyst and the odontogenic keratocyst, there is no previous report based on transforming of dentigerous cyst to orthokeratinized odontogenic cyst. We described a case of orthokeratinized odontogenic cyst originated from a dentigerous cyst in a 30-year-old female discovering accidentally in routine radiography.
An unusually extensive orthokeratinized odontogenic cyst: A case report
IP Journal of Diagnostic Pathology and Oncology
While odontogenic keratocysts (OKC) are fairly common and well-known, orthokeratinized odontogenic cysts (OOCs) are quite rare accounting for less than 1% of odontogenic cysts. The entity is characterized by the presence of a predominant orthokeratinized lining. OOC is much less aggressive as compared to OKC and simple enucleation is discerned as adequate treatment with minimal chances of recurrence. The present case report describes an extensive OOC that involved most of the angle and ramus of the mandible in a 25-year-old female.
Bilateral orthokeratinized odontogenic cyst: A rare case report and review
Journal of Oral and Maxillofacial Pathology, 2014
Orthokeratinized odontogenic cyst (OOC) is a developmental cyst of jaw and was initially considered by the World Health Organization (1992) as the uncommon orthokeratinized variant of odontogenic keratocyst (OKC). However, studies have shown that OOC has peculiar clinicopathologic aspects when compared with other developmental odontogenic cysts, especially OKC. So orthokeratinized odontogenic cyst now stands out to be a distinct entity. Clinically, it occurs as a single cyst, shows a predilection for males and is most often found in the second to the fifth decade. Its bilateral occurrence is extremely rare. The purpose of the article is to present a rare case of bilateral OOC arising in the mandible and review the literature on bilateral occurrence of this lesion.
Orthokeratinized odontogenic cyst masquerading as dentigerous cyst
International Journal of Applied and Basic Medical Research, 2016
The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumor until Wright (1981) defined it as a different entity. Recognition of OOC as a unique entity has long been due, yet its inexplicable clinical, radiographic presentation resembling dentigerous cyst due to its association to an impacted tooth, and its histological features makes it rather perplexing. This is the report of a case of OOC in relation to an impacted maxillary canine and its immunohistochemical analysis with Ki-67.
Histopathological Examination and Literature Review of Orthokeratinized Odontogenic Cyst
Open Journal of Stomatology, 2019
Background: With transitions in the disease concept of orthokeratinized odontogenic cyst (OOC), the pathogenesis and etiology have not been sufficiently elucidated. Objectives: OOC cases were reclassified and observed to understand the clinico-histopathological characteristics. In addition, literature review of OOC was performed to better organize the pathology. Materials and methods: Subjects with jawbone cysts lined by keratinized stratified squamous epithelium from 2005 to 2018 were reclassified, and clinico-histopathological findings were analyzed. Previous reports of OOC/orthokeratinized-type odontogenic keratocyst (OKC) from 1980 to 2019 were organized. Results: Five cases of OOC were diagnosed, representing 2.1% of odontogenic developmental cysts (total, 239 cases). Mean age was 37.6 years, with a female predominance. The mandibular molar area was the frequent site, and all cysts were solitary. Sixty percent involved an impacted tooth. Mean maximum diameter of the cyst was 2.2 cm. Histopathologically, 4 cases were unilocular, and partial palisading of the basal layer and scattered epithelial islands were observed in 2 cases each and formation of daughter cysts was noted in 3 cases. Previous papers described that most were unilocular and related to impacted teeth. Mean age ranged between 20 and 40 years, and the mandibular molar region was dominant. Recurrence rates were low. Conclusion: OOC shows a different biological attitude to OKC and is closer to dentigerous cyst. Meanwhile, OOC shows a similar histology of epidermoid cysts accompanying the granular layer. We thus surmised that OCC represents an independent concept as an odontogenic developmental cyst.
Journal of Oral and Maxillofacial Pathology
Orthokeratinized odontogenic cyst (OOC) is an uncommon odontogenic cyst. It has been categorized as a subtype of odontogenic keratocyst (OKC). In 2005, it was classified as a distinct entity. OOC should be histopathologically differentiated from OKC, which has a higher recurrence rate and lower malignant potential. In addition, OOC should be examined for malignant transformation. The epithelium of odontogenic cysts may rarely show malignant transformation. However, malignant transformation has been reported in inflammatory cysts such as the residual cyst and periapical cyst. The number of carcinomas arising from an OOC is low. This paper describes eight cases of OOC; out of which, two showed the development of squamous cell carcinoma from their epithelial lining.
An Aggressive Orthokeratinized Odontogenic Cyst of the Mandible: A Case Report
IOSR Journal of Dental and Medical Sciences, 2013
Orthokeratinized odontogenic cyst (OOC) is a developmental cyst that occurs in the jaw. it was initially defined by the world health organization as the orthokeratinized variant of odontogenic keratocyst (OKC). However, studies have shown that OOC has a peculiar clinicopathologic aspects when compared with other developmental odontogenic cysts, especially OKC's. The orthokeratinized odontogenic cyst is a distinct clinicopathologic entity and is histologically characterized by a thin, uniform, epithelial lining with orthokeratinization. Clinically, the orthokeratinized cyst is a single cyst, shows a predilection for males, and is most often found in the second to the fifth decade. It is not a dentigerous cyst but is often mistaken for a dentigerous cyst because of its association with unerrupted or impacted tooth in the posterior mandible. It exhibits lower clinical aggressiveness compared to its counterpart OKC. The purpose of the article is to present a case of large aggressive OOC in the anterior mandible and to highlight the importance of, distinguishing it from the more commonly occurring OKC or keratocystic odontogenic tumour (KCOT).