Identification and characterization of small compound inhibitors of human FATP2 (original) (raw)

Targeting the Fatty Acid Transport Proteins (FATP) to Understand the Mechanisms Linking Fatty Acid Transport to Metabolism

Paul Sandoval P

Immunology, Endocrine & Metabolic Agents - Medicinal Chemistry (formerly Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents), 2009

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Development and Validation of a High-Throughput Screening Assay for Human Long-Chain Fatty Acid Transport Proteins 4 and 5

Journal of Biomolecular Screening, 2010

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Fatty acid transport proteins: targeting FATP2 as a gatekeeper involved in the transport of exogenous fatty acids

Med. Chem. Commun., 2016

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Disruption of the Saccharomyces cerevisiae Homologue to the Murine Fatty Acid Transport Protein Impairs Uptake and Growth on Long-chain Fatty Acids

Journal of Biological Chemistry, 1997

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Human Fatty Acid Transport Protein 2a/Very Long Chain Acyl-CoA Synthetase 1 (FATP2a/Acsvl1) Has a Preference in Mediating the Channeling of Exogenous n-3 Fatty Acids into Phosphatidylinositol

Concetta Dirusso

Journal of Biological Chemistry, 2011

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Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids

Biochemical and Biophysical Research Communications, 2013

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Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity

Biochemical and biophysical research communications, 2015

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FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase

AJP: Endocrinology and Metabolism, 2010

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Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4

Thomas Herrmann

Journal of Cell Science, 2006

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Comparative Biochemical Studies of the Murine Fatty Acid Transport Proteins (FATP) Expressed in Yeast

Concetta Dirusso

Journal of Biological Chemistry, 2005

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A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors

Concetta Dirusso

Analytical Biochemistry, 2005

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The Human Fatty Acid Transport Protein-1 (SLC27A1; FATP-1) cDNA and Gene: Organization, Chromosomal Localization, and Expression

J. Najib, Jean-Charles Fruchart

Genomics, 2000

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SSO and other inhibitors of putative fatty acid (FA) transport do not affect FA transport but disrupt FA metabolism

Journal of Lipid Research

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Enzymatic Properties of Purified Murine Fatty Acid Transport Protein 4 and Analysis of Acyl-CoA Synthetase Activities in Tissues from FATP4 Null Mice

Thomas Herrmann

Journal of Biological Chemistry, 2005

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High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

Concetta Dirusso

The Journal of Lipid Research, 2008

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The Fatty Acid Transport Function of Fatty Acid-Binding Proteins

Biochimica et Biophysica Acta (BBA)-Molecular …, 2000

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Adipocyte-specific Inactivation of Acyl-CoA Synthetase Fatty Acid Transport Protein 4 (Fatp4) in Mice Causes Adipose Hypertrophy and Alterations in Metabolism of Complex Lipids under High Fat Diet

Journal of Biological Chemistry, 2011

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Functional domains of the fatty acid transport proteins: Studies using protein chimeras

Concetta Dirusso

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2008

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Role of FATP in parenchymal cell fatty acid uptake

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2004

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New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae

Proceedings of the Nutrition Society, 2004

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Characterization of the fatty acid transport protein 4 (FATP4) gene and functional assessment of FATP4 as a very long chain acyl-CoA synthetase

Thomas Herrmann

Gastroenterology, 2001

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Targeting fatty acid uptake and metabolism in cancer cells: A promising strategy for cancer treatment

Prasenjit Bhowmik

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Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans

Geneviève Cordonnier

American Journal of …, 2000

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Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins?

Molecular and cellular biochemistry, 2002

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Fatty Acid Transport in Saccharomyces cerevisiae. DIRECTED MUTAGENESIS OF FAT1 DISTINGUISHES THE BIOCHEMICAL ACTIVITIES ASSOCIATED WITH Fat1p

Concetta Dirusso

Journal of Biological Chemistry, 2002

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Evidence for protein-mediated fatty acid efflux by adipocytes

Acta Physiologica, 2011

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Increasing skeletal muscle fatty acid transport protein 1 (FATP1) targets fatty acids to oxidation and does not predispose mice to diet-induced insulin resistance

Oksana Gavrilova

Diabetologia, 2011

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