Congenital granular cell epulis: report of a case and review of the literature (original) (raw)

Congenital granular cell epulis: a case report with immunohistochemistry

گۆڤاری ههولێر بۆزانستی پزیشکی ددان, 2021

Congenital granular cell epulis is a rare benign tumor of soft tissue in newborns. In most cases it arises from the anterior part of the maxillary alveolar ridge and is ten times more prevalent in females than males. We present a case report of a 2-month-old female infant, who presented with a mass on the gingival mucosa. The lesion was completely removed by simple excision. A final diagnosis of a congenital granular cell tumor was made by histologic and immunohistochemical examination.

Histogenesis and clinical analysis of 2 cases of congenital gingival granular cell tumour

Journal of clinical and diagnostic research : JCDR, 2015

Dentistry for babies aims to contribute to the formation of a generation with fewer dental problems, higher quality of oral health and more aware of the importance of prevention. The congenital gingival granular cell tumour (CGCT) is a rare benign soft tissue tumour in the newborn that can lead to respiratory difficulties and feeding. The aim of this work was to report two cases of CGCT in babies and discuss the clinical and histological differential diagnosis and their treatment, as well as the importance of knowledge of this pathology for dentists. Clinical features and treatment approaches are presented and discussed. The surgical approach improved the child quality of life and restored the parent's confidence and emotional stability. Knowledge of this pathology helps in better diagnosis and treatment, which lead to a better quality of life of children and return confidence and emotional stability to parents.

Congenital granular-cell tumor of the gingiva

Pediatric Surgery International, 1998

Congenital granular cell tumors of the gingiva (synonyms: congenital myoblastoma, congenital epulis) originate from the alveolar ridge in newborns. They are rare granular-cell tumors with benign histology. The main dierential diagnosis is epignathus (oral teratoma). Early surgical excision is recommended due to a risk of airway obstruction and diculty feeding.

A case report of a huge congenital granular cell epulis operated under local anesthesia

The Pan African medical journal, 2012

Congenital granular cell epulis (CGCE) is a very rare benign soft tissue lesion of the neonate, it most frequently located on the anterior maxillary alveolar ridge. It has a female predilection. It is a tumor with no tendency to recur after excision. The exact histogenesis of this tumor remains unresolved and it may be hamartomata.

Congenital granular cell epulis: Pattern of presentation in four Nigerian tertiary hospitals

International Journal of Medical and Dental Case Reports, 2018

This study aims to report seven cases of congenital granular cell epulis (CGCE) diagnosed in four teaching hospitals in Southwestern Nigeria over a period of 8 years. CGCE is a rare lesion that presents exclusively at birth. It is benign, but often presents an unsightly appearance, and may be associated with difficulty in feeding, thus early presentation of cases for treatment. The records of the oral and maxillofacial pathology departments of four Nigerian teaching hospitals were assessed for lesions with histological diagnosis of CGCE. Data inclusive of age, gender, anatomic site, and mode of treatment was retrieved and analyzed with SPSS version 21. Seven cases were identified from the four teaching hospitals. All cases occurred in females with an average period of presentation at 7 days after birth. Most of the cases (71.4%) occurred on the maxillary alveolar ridge. Six cases presented as a single pedunculated or sessile lesion, while in one case, three nodules were seen. Although spontaneous regression has been documented in literature, all our cases had surgical excision under local anesthesia without complications or recurrence. All our cases were diagnosed in females and 71.4% were on the maxillary alveolar ridge.

Congenital Gingival Granular Cell Tumor. A Case Report

The Journal of Nihon University School of Dentistry, 1993

Congenital gingival granular cell tumor is a rare benign lesion of uncertain origin, which has been found only in newborn infants. This article describes one such case. Our immunohistochemical study employing antibodies against S-100 protein, epithelial membrane antigen, carcinoembryonic antigen, wide-spectrum keratin, desmin and vimentin yielded data supporting the theory of a mesenchymal cell origin for this lesion.

Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor

Journal of Pediatric Surgery, 2006

Objective: Congenital gingival granular cell tumor (CGCT) is a rare benign lesion appearing at birth on the alveolar median ridge of the maxilla. Etiology is still unclear because spontaneous regression of the lesion is rare. Methods: The present report describes 2 cases of neonatal CGCT, highlighting benefits of ultrasonography to treatment of the prenatally diagnosed lesion. Results: The patients immediately underwent surgical exeresis. Pathology revealed a tumor of large polyedric cells with vacuolar central nuclei and eosinophil granular cytoplasm. Conclusions: Prenatal diagnosis is fundamental in the therapeutic approach to CGCT: ultrasonography methodologies allow diagnosis of the lesion in the uterus at the 36th gestational week, thus also allowing planning of delivery and, immediately later, the surgical treatment. That permits planning of delivery in a third-level center with considerable benefit for both the mother and the newborn. D

Congenital Epulis: Case Report and Literature Review

Indian Journal of Neonatal Medicine and Research, 2013

Congenital epulis of the neonate (CE) or congenital gingival granular cell tumor (CGCT) is a rare, benign, mostly single tumor. This arises from gingival mucosa, most commonly from maxillary alveolar ridge, with predominance in females. The histogenesis of the lesion remains unclear. The present report describes a case of congenital epulis in the maxillary alveolar ridge. This lesion was causing feeding difficulties and was excised under general anaesthesia.

Congenital epulis: a report of two cases and review of the literature

International Journal of Medicine and Biomedical Research, 2016

Background: Congenital epulis of the newborn is a rare benign soft-tissue tumour of the gingival, which is also called gingival granular cell tumour of the newborn. These slow growing soft tissue tumors affect the gingivae of a new born child. It is essential to document the presentation and the management of this lesion because of its rare nature. Aim: To highlight the clinical presentation, diagnosis and management of the lesion. Methods: Two clinical cases of congenital epulis were used to illustrate the presentation and surgical management of the lesion. Findings: The first clinical case is a one month old female child with a protruding gum tumour on the anterior alveolar process of the mandible. The second case is a one week old male child with a gingival growth on the anterior alveolar process of the mandible. All the tumours were surgically excised under local anaesthesia. Conclusion: Congenital epulis could interfere with the functions of the oral cavity. Therefore, it is imperative to surgically excise it when diagnosed. Following the management of the two cases presented, it is essential that the mouth of all newborns must be examined to rule out any such lesion.