Congenital granular cell epulis: a case report with immunohistochemistry (original) (raw)

Congenital granular cell lesion: A rare tumor of new born

Journal of Oral and Maxillofacial Pathology, 2013

Congenital granular cell tumor (CGCT), or congenital epulis, is an uncommon benign soft tissue lesion that usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. The histogenesis and clinical history of the lesion remains obscure. Treatment involves surgical excision and recurrences are rare. The present report describes a case of congenital granular cell lesion (CGCL) in the anterior segment of maxillary alveolar ridge of a 2-month-old female. This lesion was causing feeding problem and was excised under local anesthesia, with no recurrence even after 3 years.

Congenital granular cell epulis—a case report

Oral and Maxillofacial Surgery Cases, 2015

Congenital granular cell epulis (CGCE) is an uncommon benign lesion found in newborns. It has predominance for females with an 8:1 ratio in relation to males and is exclusively encountered in the oral cavity. The most affected oral site is located around the canine/incisor region of the maxillary alveolar ridge, where the lesion arises from the soft tissue as a solitary pedunculated mass. CGCE's histogenesis remains obscure and controversial. We present a rare case of 2 separate CGCE lesions adjacent to each other measuring 23 Â 18 Â 10 and 15 Â 10 mm, positioned facially on the right maxillary alveolar process. The patient, a 2-day-old female newborn, did not experience any serious difficulty regarding breathing or deglutition. Complete surgical excision was the treatment of choice in this case, and the procedure was performed under both general and local anesthesia. Histologic and immunohistochemical analysis confirmed the diagnosis of CGCE. The patient showed satisfactory postoperative healing and excellent health at both the 10-day recall appointment and the 6-month follow-up.

Congenital granular-cell tumor of the gingiva

Pediatric Surgery International, 1998

Congenital granular cell tumors of the gingiva (synonyms: congenital myoblastoma, congenital epulis) originate from the alveolar ridge in newborns. They are rare granular-cell tumors with benign histology. The main dierential diagnosis is epignathus (oral teratoma). Early surgical excision is recommended due to a risk of airway obstruction and diculty feeding.

Congenital granular cell tumor (congenital epulis): a lesion of multidisciplinary interest

Medicina oral, patología oral y cirugía bucal, 2007

Congenital granular cell tumor (CGCT), or congenital epulis, is a very uncommon benign soft tissue lesion that usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. We report a case of a 3-day-old female newborn, who presented an intraoral tumor mass which was protruding from her mouth, and compromising feeding. Under general anesthesia, the lesion was completely removed and the patient had an uneventful postoperative course. Clinical features and treatment approaches are presented and discussed, emphasizing the necessity of a multidisciplinary approach in such cases.

Congenital Granular Cell Tumor of a Newborn: A Case Report

Indian Journal of Neonatal Medicine and Research, 2016

Congenital Granular Cell Tumour (CGCT) is a rare benign soft tissue tumour of newborn, different from adult GCT. The tumour has a strong predilection for the maxillary alveolar ridge with a female preponderance. Here we report an unusual case of congenital granular cell epulis in the mouth of a 2 hour old female newborn. She had a round, soft, pedunculated mass measuring (2x 2x1) cm. which was causing feeding difficulty. This case was reported as congenital granular cell epulis. We are presenting this case because of its rare nature and uncommon presentation at this age.

Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor

Journal of Pediatric Surgery, 2006

Objective: Congenital gingival granular cell tumor (CGCT) is a rare benign lesion appearing at birth on the alveolar median ridge of the maxilla. Etiology is still unclear because spontaneous regression of the lesion is rare. Methods: The present report describes 2 cases of neonatal CGCT, highlighting benefits of ultrasonography to treatment of the prenatally diagnosed lesion. Results: The patients immediately underwent surgical exeresis. Pathology revealed a tumor of large polyedric cells with vacuolar central nuclei and eosinophil granular cytoplasm. Conclusions: Prenatal diagnosis is fundamental in the therapeutic approach to CGCT: ultrasonography methodologies allow diagnosis of the lesion in the uterus at the 36th gestational week, thus also allowing planning of delivery and, immediately later, the surgical treatment. That permits planning of delivery in a third-level center with considerable benefit for both the mother and the newborn. D

Congenital granular cell epulis: report of a case and review of the literature

2019

INTRODUCTION: Congenital granular cell epulis (CGCE) is a benign soft tissues lesion of gingival origin 1,2 occurring in the neonates. CGCE is very rare and 2,3 unique and was first described in 1871 by a German 4 pathologist, Ernst Christian Neumann. It is an intriguing lesion with unclear aetiology, histogenesis and natural history. Several theories have been suggested, namely myoblastic, odontogenic, n e u r o g e n i c , f i b r o b l a s t i c , h i s t i o c y t i c , a n d 3,5

Congenital Gingival Granular Cell Tumor. A Case Report

The Journal of Nihon University School of Dentistry, 1993

Congenital gingival granular cell tumor is a rare benign lesion of uncertain origin, which has been found only in newborn infants. This article describes one such case. Our immunohistochemical study employing antibodies against S-100 protein, epithelial membrane antigen, carcinoembryonic antigen, wide-spectrum keratin, desmin and vimentin yielded data supporting the theory of a mesenchymal cell origin for this lesion.