D. 4–CELLULAR and Molecular Mechanisms of Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (Als) (original) (raw)

D.4 - CELLULAR AND MOLECULAR MECHANISMS OF MOTOR NEURON DEGENERATION IN AMYOTROPHIC LATERAL SCLEROSIS (ALS) D. 4a - Molecular mechanisms of mutant SOD1 toxicity in ALS cellular models D. 4b - Role of the VAPB Gene in the pathogenesis of ALS

Francesca Navone

2000

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Mutant SOD1 Instability: Implications for Toxicity in Amyotrophic Lateral Sclerosis

Lawrence Hayward

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Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS

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Scuola di Dottorato in Scienze Farmacologiche XXVIII ciclo ROLE OF MUTANT VAPB IN THE PATHOGENESIS OF AMYOTROPHIC LATERAL SCLEROSIS : GAIN OR LOSS OF FUNCTION ?

Francesca Navone

2015

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Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014

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Identifying, Targeting, and Exploiting a Common Misfolded, Toxic Conformation of SOD1 in ALS: A Dissertation

Melissa Rotunno

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The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

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SOD1 mutations in amyotrophic lateral sclerosis

Stefania Battistini

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Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1

Dandeson Alfred Cleveland

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A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

Elizabeth Fisher

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Philippe Corcia

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Wild-type human SOD1 overexpression does not accelerate motor neuron disease in mice expressing murine Sod1G86R

Jean-Pierre Julien

Neurobiology of Disease, 2010

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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

Diane McKenna-Yasek

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Neuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS

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SOD1 in ALS: Taking Stock in Pathogenic Mechanisms and the Role of Glial and Muscle Cells

Maria Massimino

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Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

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Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis

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