The roles of amyloid precursor protein (APP) in neurogenesis (original) (raw)
The roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease
Zhi-cheng Xiao
Cell Adhesion & Migration, 2011
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Investigating the Role of the Amyloid Precursor Protein in the Pathogenesis of Alzheimer's Disease
Roger Lefort
2011
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Alzheimer’s disease: a dysfunction of the amyloid precursor protein
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Factors influencing the processing and function of the amyloid β precursor protein—a potential therapeutic target in Alzheimer's disease?
Kieran Breen
Pharmacology & Therapeutics, 2000
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Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation
Joakim Strandberg
Scientific Reports, 2016
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Alzheimer's disease: dysfunction of a signalling pathway mediated by the amyloid precursor protein?
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The role of amyloid precursor proteins : studies using neurons generated from wild-type and mutant embryonic stem cells
Miriam Bibel
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The -Amyloid Precursor Protein of Alzheimer's Disease Enhances Neuron Viability and Modulates Neuronal Polarity
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Abnormalities of Amyloid Precursor Protein in the Etiology of Alzheimer's disease
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Studies of Amyloidβ-Protein Precursor Expression in Alzheimer's Disease
Rudy Tanzi
Annals of the New York Academy of Sciences, 1991
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The amyloid precursor protein gene: a neuropeptide gene with diverse functions in the central nervous system
Peter Panegyres
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Physiological effects of amyloid precursor protein and its derivatives on neural stem cell biology and signaling pathways involved
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Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts
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Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer's disease
Anahi Bignante
Neurobiology of Aging, 2013
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Overexpression of Amyloid Precursor Protein Alters Its Normal Processing and is Associated With Neurotoxicity
richard watkins
Biochemical and …, 1992
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The amyloid-β precursor protein: integrating structure with biological function
Constanze Reinhard
The EMBO Journal, 2005
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Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
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The Amyloid β-Protein Precursor and Alzheimers Disease. Therapeutic Approaches
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The processing and biological function of the human amyloid precursor protein (APP): lessons from different cellular models
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Differential brain expression of the Alzheimer's amyloid precursor protein
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The EMBO Journal, 1989
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Processing of Amyloid Precursor Protein in Human Primary Neuron and Astrocyte Cultures
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Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study
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Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
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Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation
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Disruption of neurogenesis by amyloid β-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
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The b-Amyloid Precursor Protein of Alzheimer's Disease Enhances Neuron Viability and Modulates Neuronal Polarity
Edward Ko
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Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro
Philippe Hantraye
The Journal of Cell Biology, 1995
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Hypothesis Neurogenesis Makes a Crucial Contribution to the Neuropathology of Alzheimer's Disease
John Young
Journal of Alzheimer's Disease Reports, 2020
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Adult Neurogenesis: A Potential Tool for Early Diagnosis in Alzheimer's Disease
Miguel A. Lopez-Toledano
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