The putative role of leukotrienes in experimental atherogenesis (original) (raw)

Patophysiology of atherosclerosis based on research on apoE-knockout mice and their usefulness in checking new antiatherosclerotic agents

Jacek Jawien

Acta Angiologica, 2009

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The current view on the role of leukotrienes in atherogenesis

Jacek Jawien

PubMed, 2010

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Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability

Anders Wetterholm, Min Wan, Bengt Samuelsson

Proceedings of the National Academy of Sciences, 2006

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Involvement of 15-lipoxygenase in early stages of atherogenesis

H. Kuhn

Journal of Experimental Medicine, 1994

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Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

H. Robenek, Anja Urbach

Proceedings of the National Academy of Sciences, 2003

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Lipoxygenase Pathways in Atherogenesis

Lei Zhao

Trends in Cardiovascular Medicine, 2004

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The two faces of the 15-lipoxygenase in atherosclerosis

Martin Hersberger

Prostaglandins, leukotrienes, and essential fatty acids, 2007

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Leukotrienes in the atherosclerotic cardiovascular diseases — a systematic review

Mikołaj Maga

Acta Angiologica

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Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties

Steven Feinmark

British Journal of Pharmacology, 1997

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Effect of a Polyunsaturated Fatty Acid Mimetic on the Development of Atherosclerosis in the Apoe Deficient Mouse

Fatemeh Moheimani

2005

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Leukotrienes and atherosclerosis: new roles for old mediators

Venkatakrishna Jala

Trends in Immunology, 2004

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Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice

Michael Oda, Anne Clermont

Journal of lipid research, 2002

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Is there a role for 15-lipoxygenase in atherogenesis?

Steven Feinmark

Biochemical Pharmacology, 1997

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Leukotriene Signaling in Atherosclerosis and Ischemia

Magnus Back

Cardiovascular Drugs and Therapy, 2009

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Dietary -Lipoic Acid Supplementation Inhibits Atherosclerotic Lesion Development in Apolipoprotein E Deficient and Apolipoprotein E/Low-Density Lipoprotein Receptor Deficient Mice

Tory Hagen, Timothy McMillen

Circulation, 2008

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Differential Leukotriene Receptor Expression and Calcium Responses in Endothelial Cells and Macrophages Indicate 5-Lipoxygenase-Dependent Circuits of Inflammation and Atherogenesis

Anja Urbach

Arteriosclerosis, Thrombosis, and Vascular Biology, 2003

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Amino Acid Differences in the Deduced 5-Lipoxygenase Sequence of CAST Atherosclerosis-Resistance Mice Confer Impaired Activity When Introduced Into the Human Ortholog

H. Kuhn

Arteriosclerosis, Thrombosis, and Vascular Biology, 2003

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Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice

Kazuhiko Tanaka

Journal of atherosclerosis and thrombosis, 2009

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Identification of 5Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice

jack wong

2000

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Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis

Jan Borén

PLoS ONE, 2012

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Absence of 12/15Lipoxygenase Expression Decreases Lipid Peroxidation and Atherogenesis in Apolipoprotein E-Deficient Mice

Lei Zhao

2010

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The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm

Lei Zhao

Nature Medicine, 2004

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A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm

Dieter Steinhilber

British Journal of Pharmacology, 2011

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Inflammatory signaling through leukotriene receptors in atherosclerosis

Magnus Back

Current Atherosclerosis Reports, 2008

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Critical Role of Macrophage 12/15-Lipoxygenase for Atherosclerosis in Apolipoprotein E–Deficient Mice

Brian Harry

2014

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Differential Leukotriene Constrictor Responses in Human Atherosclerotic Coronary Arteries

Michael Dashwood

Circulation, 1998

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Time-dependent changes to lipids and antioxidants in plasma and aortas of apolipoprotein E knockout mice

Paul Witting

The Journal of Lipid Research

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Inhibition by a coantioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low density lipoprotein receptor gene double knockout mice

Paul Witting

The FASEB Journal

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Review paper Apolipoprotein E knockout mice:an experimental model to study inflammatorymechanisms of atherosclerosis and to screena putative anti-atherogenic properties of drugs

Jacek Jawien

Central European Journal of Immunology, 2012

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Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice

Rafał Olszanecki

European Journal of Clinical Investigation, 2006

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Mouse models of experimental atherosclerosis

Ryszard Korbut

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004

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Endothelial cells can synthesize leukotriene B

George Johnson

Journal of Vascular Surgery, 1990

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LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit

Giovanni Di Salvo

Journal of Physiology and Biochemistry, 2012

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ApoE-Knockout Mice: What are New Achievements of this Model of Atherosclerosis?

Jacek Jawien

Acta Scientific Pharmaceutical Sciences, 2021

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12/15Lipoxygenase Gene Disruption Attenuates Atherogenesis in LDL Receptor-Deficient Mice

Lei Zhao

Circulation, 2001

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