Roflumilast-induced Local Vascular Injury Is Associated with a Coordinated Proteome and Microparticle Change in the Systemic Circulation in Pigs
Judit Cubedo, Laura Casaní, Javier Crespo
Toxicologic pathology, 2014
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The stellate vascular smooth muscle cell phenotype is induced by IL-1β via the secretion of PGE2 and subsequent cAMP-dependent protein kinase a activation
karl Blirando
Biochimica et biophysica acta, 2015
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TNF-α mediated proliferation of vascular smooth muscle cells involves Raf-1 mediated inactivation of Rb and transcription of E2F1 regulated genes
Srikumar Chellappan
Cell …, 2012
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Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State
Indika Edirisinghe
Arteriosclerosis Thrombosis and Vascular Biology, 2009
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Factor–Stimulated Vascular Smooth Muscle Cell Function and Injury-Induced Neointima Formation
BRENDA ALEX
2013
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Oxidative stress induces early-onset apoptosis of vascular smooth muscle cells and neointima formation in response to injury
Si Pham
Bioscience reports, 2015
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Engineering the Response to Vascular Injury: Divergent Effects of Deregulated E2F1 Expression on Vascular Smooth Muscle Cells and Endothelial Cells Result in Endothelial Recovery and Inhibition of Neointimal Growth
David Goukassian
Circulation Research, 2003
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Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
Mark Bond
Cells
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8-Chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima formation induced by balloon injury in vivo
Ciro Indolfi
Journal of the American College of Cardiology, 2000
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NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells
Saima Muzaffar
Journal of Cellular Physiology, 2012
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A phosphodiesterase 4 inhibitor, roflumilast N-oxide, inhibits human lung fibroblast functions in vitro
Giovanni Rossi
Pulmonary Pharmacology & Therapeutics, 2010
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formation induced by balloon injury in vivo 8-Chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima
Ciro Indolfi
2010
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IL-4-induced Oxidative Stress Upregulates VCAM-1 Gene Expression in Human Endothelial Cells
Andrew Neish
Journal of Molecular and Cellular Cardiology, 2001
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COX-2 and cytosolic PLA2 mediate IL-1beta-induced cAMP production in human vascular smooth muscle cells
Debbie Beasley
American Journal of Physiology, 1999
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Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85αPI3K
claudia cosentino
American Journal of Physiology-Heart and Circulatory Physiology, 2009
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Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice
Syed Ghulam Abbas Zaidi
Journal of Clinical Investigation, 2000
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Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85 PI3K
Angelo Leone
AJP: Heart and Circulatory Physiology, 2009
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Vascular cell-adhesion molecule-1 plays a central role in the proangiogenic effects of oxidative stress
Jikui Shen
Proceedings of the National Academy of Sciences, 2011
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The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
Celine Gongora
PloS one, 2017
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Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells
Simona-Adriana Manea
Free Radical Biology and Medicine, 2012
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Nuclear Factor of Activated T Cells c1 Mediates p21-activated Kinase 1 Activation in the Modulation of Chemokine-induced Human Aortic Smooth Muscle Cell F-actin Stress Fiber Formation, Migration, and Proliferation and Injury-induced Vascular Wall Remodeling
Ravisekhar Gadepalli
Journal of Biological Chemistry, 2013
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Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability
Andrew Issekutz
British Journal of Pharmacology, 2007
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Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells
Andrew Newby, Aparna Duggirala
Journal of Molecular and Cellular Cardiology, 2014
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The immunoadhesin glycoprotein VI-Fc regulates arterial remodelling after mechanical injury in ApoE-/- mice
Dorothea Siegel-Axel
Cardiovascular Research, 2008
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Flt-1 expression influences apoptotic susceptibility of vascular smooth muscle cells through the NF- B/IAP-1 pathway
Sandro Falco
Cardiovascular Research, 2010
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Biomechanically Induced Gene iex-1 Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation
Daniel Simon
Circulation Research, 2003
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Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms
Younghoon Go
Redox Biology, 2014
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Noncatalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage
Régis BLAISE
Journal of Cell Science, 2020
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Editorial: Molecular Mechanisms Protecting against Tissue Injury
Frank Wagener
Frontiers in Pharmacology, 2016
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Investigation of the molecular mechanisms preceding PDE4 inhibitor-induced vasculopathy in rats: tissue inhibitor of metalloproteinase 1, a potential predictive …
Stephan Chevalier
Toxicological …, 2007
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Engineering the Response to Vascular Injury
David Goukassian
Circulation Research, 2003
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PKA and Epac synergistically inhibit smooth muscle cell proliferation
Andrew Newby
Journal of Molecular and Cellular Cardiology, 2011
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