A rare form of the lung cancer: Mucoepidermoid carcinoma: A case report (original) (raw)
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Mucoepidermoid carcinoma of the lung: a case report and literature review
Case reports in oncological medicine, 2013
Introduction. Mucoepidermoid carcinoma (MEC) of the lung is a rare form of lung cancer that is classified into low grade and high grade based on histological features. Surgical resection is the primary treatment for low-grade MEC with excellent outcomes, while high-grade MEC is a more aggressive form of malignancy. Clinical Case. We report a case of a 46-year-old woman who presented with dyspnea on exertion. Imaging studies revealed a mass involving the right upper lobe bronchus. Bronchoscopy, surgical resection, and pathological examination revealed a low-grade MEC with tumor-free margins. No adjuvant treatment was given. Discussion. Primary pulmonary MEC is a rare type of lung cancer with only few reported cases. This patient illustrates a typical presentation for low-grade MEC wherein surgical resection is considered curative. In contrast, high-grade MEC is a more aggressive malignancy with a poorer outcome. The role of targeted therapy directed against EGFR or a novel CRTC1-MAML...
Mucoepidermoid carcinoma of the lung: a rare entity
Oxford medical case reports, 2015
A 38-year-old lady presented with mild fever and dry cough of 1 week duration. Her chest X-ray showed right middle lobe collapse and consolidation. CT thorax revealed a mass in the right middle lobe. Subsequent bronchoscopy showed a growth completely occluding the right middle lobe bronchus and extending proximally into bronchus intermedius. Right bilobectomy (middle and lower lobes) with lymphadenectomy was performed. All the histomorphological features were suggestive of a low-grade mucoepidermoid carcinoma (MEC). MEC is one of the very rare neoplasms of the lung comprising <1% of all lung tumours. Low-grade MEC has a better prognosis than high-grade tumour, the latter being similar to that of non-small-cell lung carcinoma.
Mucoepidermoid carcinoma of the lung: a case report
Journal of Cardiothoracic Surgery, 2011
Mucoepidermoid carcinoma of the lung (MEC) is a tumor of low malignant potential of bronchial gland origin. MEC and adenoid cystic carcinoma are both considered to be salivary gland-type neoplasms. MECs are comparatively rare with an incidence of all lung cancers. We recently encountered a case of this type of lung cancer. A 60-year-old man was found to have an abnormal shadow in the left lower lung field on a regular checkup for lung cancer at his company. Chest radiography and CT revealed a mass shadow measuring 30 mm in diameter in the left lower lung field. Bronchoscopy revealed a protuberant tumor in the S9 bronchus, leading to a diagnosis of low-grade MEC by transbronchial lung biopsy. He underwent left lower lobe resection and mediastinal lymph node dissection using VATS. Tumor cells had a scattering of mucus-producing epithelial components in papillary growth of stratified squamous epithelia with anisokaryosis and minimal pleomorphism, indicating a diagnosis of MEC. Because the postoperative course was good and the tumor was low-grade, no adjuvant treatment was administered. The patient has had no signs of tumor recurrence for 9 months, to date, since resection of the tumor
Metastatic mucoepidermoid carcinoma of the lung: A case report
Indian Journal of Pathology and Oncology, 2021
Mucoepidermoid carcinoma (MEC) is a rare form of lung malignancy that is classified into high-grade and low-grade according to its histological characteristics. High-grade mucoepidermoid carcinoma (HMC) is more aggressive form of malignancy which involves lymph node and distant metastasis. Here, we report a 62-year-old female with complaints of dry cough and generalized weakness was diagnosed to have high grade mucoepidermoid carcinoma of lung metastases to lymph nodes, pleura, left adrenal and skeleton. Diagnosis was confirmed by Computed Tomography (CT) which showed numerous lung nodules, biopsy revealing metastatic deposit of mucoepidermoid and Positron Emission Tomography (PET) indicating primary left lung malignancy with metastasis. Despite chemotherapy initiation, the prognosis remained poor.
Mucoepidermoid lung carcinoma: diagnostic review (Atena Editora)
Mucoepidermoid lung carcinoma: diagnostic review (Atena Editora), 2022
Mucoepidermoid carcinoma is a rare cause of primary bronchial lung malignancy. These tumors are more common in young people. The diagnosis is preferably made with Fibronchoscopy and the standard treatment for the main types of salivary gland cancer is surgical resection combined with adjuvant therapy in order to reduce failure rates. The rarity of the diagnosis and the few studies in the world literature affect the systemic therapeutic approach of these patients, constituting a challenge for the medical community.
Annals of clinical and laboratory science, 2015
Mucoepidermoid carcinoma of the lung is exceedingly rare. Our case involves a 58-year-old male who presented with shortness of breath, dysphagia, and weight loss. He denied ever smoking. Chest x-ray revealed trapped lung, and CT demonstrated a right bronchial mass. Diagnosis of lung carcinoma was made by bronchoscopic FNA biopsy. EGFR mutation was negative. Staging workup demonstrated evidence of advanced disease. Performance status was good, and it was decided to start chemotherapy and radiation for palliation. Lung carcinomas often present as an obstructing hilar mass. There are different histological grades that affect progression and survival. Though uncommon, metastatic spread has been previously reported. Studies have investigated the possible role of tyrosine kinase inhibitors in both EGFR-mutated and non-mutated cases. Unfortunately, there has been little consensus as to which therapies are most beneficial.
Mucoepidermoid tumor of the lung: CT appearance
Computerized Medical Imaging and Graphics, 1995
Mucoepidermoid tumor of the lung is a rare endobronchial neoplasm with a wide spectrum of appearance. We present a case report and describe the plain film and computed tomography (CT) findings.
Mucoepidermoid carcinoma of the lung in a 6-year-old boy
African Journal of Paediatric Surgery, 2012
Primary malignant lung tumours, especially the mucoepidermoid cancer of the bronchus, are very uncommon in childhood. Obtaining the diagnosis might be difficult due to unspecific initial symptoms but early detection and treatment is crucial for a good long-term survival. Bronchoscopy is considered the "gold standard" for making the diagnosis. The recommended therapy for a mucoepidermoid lung cancer is sleeve lobectomy with favourable overall survival after complete resection. We report the case of a 6-year-old boy with a right-upper-lobe bronchus tumour. The histological examination revealed a lowgrade mucoepidermoid carcinoma.
Mucoepidermoid carcinoma of the airways in a young adult male
Journal of Radiology Case Reports, 2017
Mucoepidermoid carcinoma (MEC) of the airways is a rare entity most often found in young patients. We present a case of a 23 year old patient with symptoms of pneumonia, which progresses to a pulmonary abscess within a week. Diagnostic work-up reveals an endobronchial obstruction by a pedunculated low grade MEC. A literature review is provided and radiological appearances are described.
Surgical Outcomes of Pulmonary Mucoepidermoid Carcinoma: A Review of 23 Cases
The Thoracic and Cardiovascular Surgeon, 2013
Introduction Pulmonary mucoepidermoid carcinoma is a rare cancer that occurs primarily in younger patients. The prognostic factors of pulmonary mucoepidermoid carcinoma are largely undetermined, especially in elderly patients. The aim of this study was to examine the clinical characteristics and prognostic factors influencing survival after surgical resection in patients with pulmonary mucoepidermoid carcinoma and also analyze the clinical manifestations and prognostic factors in elderly patients.