Understanding B-cell tolerance through the use of immunoglobulin transgenic models (original) (raw)

Maintenance and loss of self-tolerance in B cells

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B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation

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B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation 1

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Virus-Like Display of a Neo-Self Antigen Reverses B Cell Anergy in a B Cell Receptor Transgenic Mouse Model

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Self-tolerance curtails the B cell repertoire to microbial epitopes

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Recent Progress in the Understanding of B-Cell Functions in Autoimmunity

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Receptor editing: an approach by autoreactive B cells to escape tolerance

Denise Gay

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B lymphocytes may escape tolerance by revising their antigen receptors

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B lymphocyte signaling pathways in systemic autoimmunity: Implications for pathogenesis and treatment

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Receptor Editing as a Mechanism of B Cell Tolerance

Mark Schlissel

The Journal of Immunology, 2011

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Tolerance without Clonal Expansion: Self-Antigen-Expressing B Cells Program Self-Reactive T Cells for Future Deletion

Werner Müller

The Journal of Immunology, 2008

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The five dimensions of B cell tolerance

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Molecular underpinning of B-cell anergy

Yuval Yarkoni

Immunological Reviews, 2010

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B Lymphocytes Are Required for Development and Treatment of Autoimmune Diseases

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B cell receptor signaling and autoimmunity

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B-lymphocyte contributions to human autoimmune disease

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Defective B cell tolerance checkpoints in systemic lupus erythematosus

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Altered B cell signalling in autoimmunity

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Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

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Journal of Clinical Investigation, 2001

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Lupus-Specific Antiribonucleoprotein B Cell Tolerance in Nonautoimmune Mice Is Maintained by Differentiation to B-1 and Governed by B Cell Receptor Signaling Thresholds

Carlos Santiago

The Journal of Immunology, 2001

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Disruption of T Cell Tolerance to Self-Immunoglobulin Causes Polyclonal B Cell Stimulation Followed by Inactivation of Responding Autoreactive T Cells

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Endogenous antigen tunes the responsiveness of naive B cells but not T cells

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Deletion of IgG-Switched Autoreactive B Cells and Defects in Faslpr Lupus Mice

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The Journal of Immunology, 2010

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Receptor editing and genetic variability in human autoreactive B cells

Takayuki Ota

Journal of Experimental Medicine, 2015

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B lymphocytes contribute to autoimmune disease pathogenesis: current trends and clinical implications

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Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity

Rizgar Mageed

Clinical reviews in allergy & immunology, 2017

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B cell positive selection by self antigens and counter-selection of dual B cell receptor cells in the peripheral B cell pools

Maria Rosado

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An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity

Eric Sobel

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B Cell Selection and Susceptibility to Autoimmunity

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The Journal of Immunology, 2005

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