Receptor editing: an approach by autoreactive B cells to escape tolerance (original) (raw)
Development of Functional B Cells in a Line of SCID Mice with Transgenes Coding for Anti-Double-Stranded DNA Antibody
D.Charan kumar.M.tech
The Journal of Immunology, 2006
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B lymphocytes may escape tolerance by revising their antigen receptors
Marko Radic
Journal of Experimental Medicine, 1993
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B cells are anergic in transgenic mice that express IgM anti-DNA antibodies
Hilde Cheroutre
European Journal of Immunology, 1993
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Alternative mechanisms of receptor editing in autoreactive B cells
Olga Kalinina
Proceedings of the National Academy of Sciences, 2011
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Persistence of partially functional double-stranded (ds) DNA binding B cells in mice transgenic for the IgM heavy chain of an anti-dsDNA antibody
Linda Spatz
International …, 2002
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Understanding B-cell tolerance through the use of immunoglobulin transgenic models
chandra mohan
Immunologic Research, 2007
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B Cell Deletion, Anergy, and Receptor Editing in “Knock In” Mice Targeted with a Germline-Encoded or Somatically Mutated Anti-DNA Heavy Chain
Klaus Rajewsky
The Journal of Immunology
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Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens
Raul Torres
The Journal of …, 2005
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Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes
Klaus Rajewsky
Proceedings of the National Academy of Sciences, 2000
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Positive and negative selection of antigen-specific B cells in transgenic mice expressing variant forms of the VH1 (T15) heavy chain
Philip Tucker, D. Longo
International Immunology, 2000
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Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/lpr Mice Bearing Autoantibody Transgenes
David Russell
Journal of Experimental Medicine, 1998
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Antigen Receptor Editing in Anti-DNA Transitional B Cells Deficient for Surface IgM
Marko Radic
The Journal of Immunology, 2008
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Autoimmune NZB/NZW F1 mice utilize B cell receptor editing for generating high-affinity anti-dsDNA autoantibodies from low-affinity precursors
Nurit Cohen
European Journal of Immunology, 2003
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Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern
Dongyao Ni
The Journal of Experimental Medicine, 2002
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Receptor Editing as a Mechanism of B Cell Tolerance
Mark Schlissel
The Journal of Immunology, 2011
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Expression of a Dromedary Heavy Chain-Only Antibody and B Cell Development in the Mouse
Serge Muyldermans
The Journal of Immunology, 2005
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Tolerance through indifference: autoreactive B cells to the nuclear antigen La show no evidence of tolerance in a transgenic model
Brett Aplin
The Journal of Immunology, 2003
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Phenotype on Transgenic B Cells Receptor Confers a Tolerance-Like Expression of a V Region-Less B Cell
Alf Grandien
2000
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Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo
Arnold VJ
International Immunology, 2005
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Persistence of functionally compromised anti-double-stranded DNA B cells in the periphery of non-autoimmune mice
Julie Roark
International Immunology, 1997
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Expression of a V Region-Less B Cell Receptor Confers a Tolerance-Like Phenotype on Transgenic B Cells
aimé vazquez
The Journal of Immunology, 2001
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B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen
Luc Teyton, Michael Jackson
Journal of Experimental Medicine, 1996
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Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice
Tony Marion
Journal of Experimental Medicine, 1992
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Virus-Like Display of a Neo-Self Antigen Reverses B Cell Anergy in a B Cell Receptor Transgenic Mouse Model
Bryce Chackerian
The Journal of Immunology, 2008
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Development in the Mouse Chain-Only Antibody and B Cell Expression of a Dromedary Heavy
Serge Muyldermans
2000
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Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus
Andrew Caton
Journal of Experimental Medicine, 1995
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Peripheral B Cell Tolerance and Function in Transgenic Mice Expressing an IgD Superantigen
Amanda Gavin
The Journal of Immunology, 2010
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Maintenance and loss of self-tolerance in B cells
Antonio Iglesias
Springer Seminars in Immunopathology, 2001
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Failed self-tolerance and autoimmunity in IgG anti-DNA transgenic mice
Mitchell Kronenberg
The Journal of Immunology
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Editing and escape from editing in anti-DNA B cells
Salar Khan
Proceedings of the National Academy of Sciences, 2008
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Effect of the presence of transgenic H and L chain genes on B cell development and allelic exclusion
Tam Dang
International Immunology, 1997
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