Structure of a GPCR Ligand in Its Receptor-Bound State: Leukotriene B4 Adopts a Highly Constrained Conformation When Associated to Human BLT2
Eric Guittet
Journal of the American Chemical Society, 2010
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Drug Design for G-Protein-Coupled Receptors by a Ligand-Based NMR Method
Christian Griesinger
Angewandte Chemie International Edition, 2010
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Engineering a G protein-coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state
Michel Laguerre
Protein Science, 2009
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NMR Investigation of Structures of G-protein Coupled Receptor Folding Intermediates
Ismael Mingarro
The Journal of biological chemistry, 2016
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Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments
Oliver Zerbe
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011
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Structural characterization of triple transmembrane domain containing fragments of a yeast G protein-coupled receptor in an organic : aqueous environment by solution-state NMR spectroscopy
Fred Naider
Journal of Peptide Science, 2015
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NMR Structural Studies of Domain 1 of Receptor-associated Protein
M. Migliorini
Journal of Biomolecular NMR, 2000
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Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions
Jesús Giraldo
Scientific reports, 2018
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Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition
Liam Sharp
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How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment
Harel Weinstein
Advances in experimental medicine and biology, 2014
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Conformational changes involved in G-protein-coupled-receptor activation
Kenneth A Jacobson
Trends in Pharmacological Sciences, 2008
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Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes
Dirk Basson
Scientific Reports, 2017
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Faculty of 1000 evaluation for Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
Sebastian Furness
F1000 - Post-publication peer review of the biomedical literature, 2012
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Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
Jean-alain Fehrentz
Proceedings of the National Academy of Sciences, 2012
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Influence of Lipid Composition on the Structural Stability of G-Protein Coupled Receptor
Dr. Iqbal Mahmood
Chemical and Pharmaceutical Bulletin, 2013
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Large multiple transmembrane domain fragments of a G protein-coupled receptor: Biosynthesis, purification, and biophysical studies
Fred Naider
Biopolymers, 2012
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Assessing Interactions Between a Polytopic Membrane Protein and Lipid Bilayers Using Differential Scanning Calorimetry and Solid-State NMR
Maureen Leninger
The Journal of Physical Chemistry B, 2018
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Structural basis of G protein-coupled receptor function
John Lloyd
Molecular and Cellular Endocrinology, 1999
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Ligand orientation in a membrane-embedded receptor site revealed by solid-state NMR with paramagnetic relaxation enhancement
Simon G . Patching
Organic & Biomolecular Chemistry, 2015
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Structure of a Double Transmembrane Fragment of a G-Protein-Coupled Receptor in Micelles
Oliver Zerbe
Biophysical Journal, 2009
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Cholesterol Modulates the Membrane Effects and Spatial Organization of Membrane-Penetrating Ligands for G-Protein Coupled Receptors
Harel Weinstein
Biophysical Journal, 2011
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Novel computational methodologies for structural modeling of spacious ligand binding sites of G-protein-coupled receptors: development and application to human leukotriene B4 receptor
Yoko Ishino
TheScientificWorldJournal, 2012
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Structural basis of G protein–coupled receptor–G protein interactions
Joel Karpiak
Nature Chemical Biology, 2010
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New tools for G-protein coupled receptor (GPCR) drug discovery: combination of baculoviral expression system and solid state NMR
Venkata Ratnala
Biotechnology Letters, 2006
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How ligands and signalling proteins affect G-protein-coupled receptors' conformational landscape
Sophie MARY
Biochemical Society Transactions, 2013
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Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β 2 AR
Jeffrey Liu
Proceedings of the National Academy of Sciences, 2015
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Correlated motions of conserved polar motifs lay out a plausible mechanism of G protein-coupled receptor activation
Arijit Sarkar
2020
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NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions
M. Ghitti
2014
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Solid-state NMR and molecular dynamics characterization of cannabinoid receptor-1 (CB1) helix 7 conformational plasticity in model membranes
David Janero
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009
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Conserved Mechanism of Conformational Stability and Dynamics in G-Protein-Coupled Receptors
sangbae lee
Journal of Chemical Theory and Computation, 2016
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Structural studies of fragments of G-protein coupled receptors and their ligands by NMR
Alexey Neumoin
2009
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Solution- and solid-state NMR studies of GPCRs and their ligands
Alan Goddard
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011
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