Low-Voltage, Low-Area, nW-Power CMOS Digital-Based Biosignal Amplifier (original) (raw)

DESIGN OF LOW POWER OPERATIONAL TRANSCONDUCTANCE AMPLIFIER FOR BIOMEDICAL APPLICATIONS

This paper presents the design of folded cascode operational transconductance amplifier (OTA). This design has been implemented in 0.18um CMOS Technology using Cadence. Spectre simulation shows that the OTA has flat gain of 47dB from 1Hz to 100 KHz frequency, indicating stability of OTA, noise ranges as 22.49769nV/ at 10Hz to 66.89128fV/ at 1MHz and average power as 0.770mW. In this paper, we will be studying the design concepts, analysis of operational transconductance amplifier which is used for recording the bio signals. This paper plays a key role in real time applications for equipment designing of ECG, EEG, EMG, ENG devices. It is also used in recording and also for treatment of Paralysis, Epilepsy, Neuro diseases etc.,

A low power sensor signal processing circuit for implantable biosensor applications

Smart Materials and Structures, 2007

A low power sensor read-out circuit has been implemented in 0.35 μm CMOS technology that consumes only 400 μW of power and occupies an area of 0.66 mm 2. The circuit is capable of converting the current signal from any generic biosensor into an amplitude shift keying (ASK) signal. The on-chip potentiostat biases the chemical sensor electrodes to create the sensor current which is then integrated and buffered to generate a square wave with a frequency proportional to the sensor current level. A programmable frequency divider is incorporated to fix the ASK envelope frequency to be inbetween 20 Hz and 20 kHz, which is within the audible range of human hearing. The entire transmitter block operates with a supply voltage as low as 1.5 V, and it can be easily powered up by an external RF source. Test results emulate the simulation results with good agreement and corroborate the efficacy of the designed system.

A HIGH CMRR, LOW-POWER OPERATIONAL TRANSCONDUCTANCE AMPLIFIER WITH 0.18μM CMOS TECHNOLOGY

IASET, 2013

This paper represent an Operational Transconductance Amplifier (OTA) which is a basic building block in many analog circuit such as in data converter’s (ADC &DAC), biquad filter design and instrumentation amplifiers. This OTA is implemented using 0.18μm CMOS technology with cadence environment and it has ±1.25v power supply with biasing current of 33nA. OTA has been simulated with virtuoso simulator and simulation results are measured. Post layout simulations for a 1 pF load capacitance shows that OTA achieves a gain bandwidth of 270 KHz at a phase margin 68.43° with 90.27 dB DC gain. This OTA is having CMRR of 154 dB, PSRR of 119 dB, Power dissipation of 29.58nW and Slew Rate 2.49 V/μsec.

Analysis and design of a highly linear CMOS OTA for portable biomedical applications in 90 nm CMOS

Microelectronics Journal, 2017

This paper presents the analysis and design of a new CMOS highly linear digitally programmable operational transconductance amplifier (DPOTA). The proposed DPOTA is used to design a fourth-order low pass filter for a portable Electroencephalogram (EEG), Electrocardiogram (ECG) and Electromyography (EMG) detection systems. The performance of the proposed DPOTA and the low pass filter is validated through simulation results using 90 nm CMOS technology under a balanced 1.2 V supply voltage. The transconductance value of the proposed DPOTA can be controlled, from 25 nA/V to 400 nA/V, by a 4-bit digital word. The IM3 of the proposed DPOTA is 45 dB with two single tones at frequency 60 Hz and 80 Hz and an amplitude of 20 mV p−p each. The low pass filter cutoff frequency can be adjusted to 107 Hz, 257 Hz, and 537 Hz. The third-order harmonic distortion (HD3) of the filter is 51 dB for 20 mV p−p at 100 Hz sinusoidal input signal.

Low-power architecture for integrated CMOS bio-sensing

2017 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2017

Integrated CMOS bio-sensing aims to design and to develop complete lab-on-chip systems. Distributed wireless sensors, at the micrometer scale, can be directly interfaced with the surrounding biological environment. In this scenario, the major challenges to be faced are devices size, power consumption, and an effective communication/system overall architecture. We propose therefore a complete and effective sensors/system architecture (data acquisition, encoding, and transmission), along with examples and results from preliminary works. The system leverages on an event-based (quasi-digital) paradigm, where analog information is mapped onto the timings of digital addressevents, so to improve the communication robustness while retaining the full information content.

A 21nW CMOS Operational amplifier for Biomedical Application

In this paper CMOS operational amplifier using a two stage has been enunciated for low power device application by using it in subthreshold region. The proposed Op amp shows high gain as well as moderate UGB using capacitor compensation technique circuit. It is operated on rail to rail power supply of ±500mV. This amplifier is highly useful for biomedical application due to low power consumption. The designed operational amplifier gain is 48dB, bandwidth is 29 KHz and phase margin is 61O, and slew rate is 50.6V/µS with 21 nW power consumption. This circuit is designed using Cadence analog & digital system design tools of UMC 90nm CMOS technology.

A low power 100MΩ CMOS front-end transimpedance amplifier for biosensing applications

2010 53rd IEEE International Midwest Symposium on Circuits and Systems, 2010

In this paper, the design, implementation and simulation of a highgain, lowpower, lownoise CMOS frontend transimpedance amplifier (TIA) is presented for interfacing with a biosensor array and analog neural circuits. An improved capacitivefeedback TIA topology is used with an active load to obtain a 100MΩ transimpedance gain, 1MHz bandwidth, 158fA/rt(Hz) inputreferred current noise at sensing frequency, near 0º phase shift and 1V peaktopeak output swing. The proposed circuit dissipates 132μW from a 1.8V supply and the circuit is implemented in a standard 0.18μm CMOS 1P6M technology.

A Low Noise Amplifier Suitable for Biomedical Recording Analog Front-End in 65nm CMOS Technology

Journal of Circuits, Systems and Computers

This paper presents a fully integrated front-end, low noise amplifier (LNA), dedicated to the processing of various types of bio-medical signals, such as Electrocardiogram (ECG), Electroencephalography (EEG), Axon Action Potential (AAP). A novel noise reduction technique, for an operational transconductance amplifier (OTA), has been proposed. This adds a current steering branch parallel to the differential pair, with a view to reducing the noise contribution by the cascode current sources. Hence, this reduces the overall input-referred noise of the LNA, without adding any additional power. The proposed technique implemented in 65[Formula: see text]nm CMOS technology achieves 30 dB closed-loop voltage gain, 0.05[Formula: see text]Hz lower cut-off frequency and 100 MHz 3-dB bandwidth. It operates at 1.2[Formula: see text]V power supply and draws 1[Formula: see text][Formula: see text]A static current. The prototype described in this paper occupies 3300[Formula: see text][Formula: see ...

Ultra low power Analog-to-Digital Converter for Biomedical Devices

The biomedical devices often operate only with a battery, e.g., blood glucose monitor, pacemaker. Therefore, it is desirable to fully utilize the energy without sacrificing the performance of the system. The Analog-to-Digital Converter (ADC), as a key component of most of the biomedical devices, needs to be designed for minimum power consumption by exploring various techniques from system level to circuit level. In addition, the nature of bio-signal provides more alternatives to reduce the power.