Pharmacognosy, Phytochemical Study and Antioxidant Activity of Sterculia rubiginosa Zoll. Ex Miq. Leaves (original) (raw)
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International Research Journal Of Pharmacy, 2018
Sterculia tragacantha Lindl. plants are endemic plants existing in Papua and have the potential of secondary metabolite compounds. This research aimed to determine the antioxidant activity and fatty acid composition of S. tragacantha Lindl. leaf extract. The extract was obtained by maceration using methanol and n-hexane solvents. The antioxidant activity testing was carried out using DPPH (1,1-diphenyl 2-picrylhydrazyl) free radicals while the identification of fatty acid compounds was done using Gas Chromatography-Mass Spectrometry (GCMS). The results showed that the methanol and n-hexane extracts of S. tragacantha Lindl. leaves had a strong antioxidant activity of 2.25 ±0,09 ppm and 27,24 ± 1,25 ppm respectively. Meanwhile, the fatty acid main contents of the methanol and n-hexane extracts of S. tragacantha Lindl. leaves were Methyl palmitate, Methyl linolenate, Linolelaidic acid methyl ester, trans-9-elaidic acid methyl ester, and Methyl palmitoleate.
The Antioxidant Activity of Sterculia stipulata Korth Woods and Leaves by FRAP Method
Pharmacognosy Journal
Background: Phenol compounds and flavonoids are known have antioxidant activity. Sterculia genus has secondary metabolite rich of phenols and flavonoids. Objective: The aim of this study of the activity antioxidants of Sterculia stipulata Korth. Woods and leaves by FRAP method. Materials and methods: Extraction done using n-hexane, ethyl acetate, and methanol. The methanol extract was determined antioxidant activity using the FRAP method and also determined the total phenols content, total flavonoids, and phytochemical screening. Results: The antioxidant activity of wood extract was 4.74 ± 1.03 FeEAC (mol/g) while leaves extract 41.17 ± 1.99 FeEAC (mol/g). Total phenols content for wood extract 16.46 ± 3.51 mg GAE/g, for leaves extract 141.62 ± 10.54 mg GAE/g. The total flavonoids content for woods extract was 27.99 ± 0.62 mg QE/g for leaf extract 41.45 ± 5.83 mg QE/g. The compounds of woods and leaves are the same; it is consist of terpenoids, alkaloids, phenols, flavonoids, saponins, terpenoids, and negatives for anthraquinone. Conclusion: The antioxidant activity of the leaves of Sterculia stipulata Korth. is greater than its wood activities.
Free Radicals and Antioxidants, 2018
Background: Medicinal plants derived natural product such as alkaloids, flavonoids and terpenes. The traditional uses claim that medicinal plants of NTT are potential folk medicine but very little research has been conducted on these plants. Objective: The present study is directed towards evaluating naturally effective antioxidant of twenty-four traditional medicinal plants collected from Kupang, East Nusa Tenggara (NTT) using in vitro models. Method: The antioxidant activities were determined by using the free radical scavenging assays 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2-2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Analysis of total flavonoid and phenolic contents were expressed as Quercetin Equivalent (QE) and Gallic Acid Equivalent (GAE), respectively. Statistical methods are used in data analysis include mean or standard deviation, and regression analysis. Result: Methanol extract of Sterculia quadrifida R. Br. root exhibited the highest DPPH radical scavenging activity with IC 50 value of 3.11μg/mL, followed by Schleichera oleosa and Euphorbia hirta L. extracts with IC 50 values of 10.05 and 10.09 μg/mL, respectively. Methanol extract of S. quadrifida also showed highest ABTS radical scavenging activity with IC 50 value of 7.29 μg/mL, followed by Eugenia jambolana Lam. and Lamea grandus with IC 50 value of 9.15 and 12.29 μg/mL, respectively. S. quadrifida extract showed high flavonoid and phenolic content with 661.85 mg of GAE and 116.84 mg of QE per 100 g of extracts. Conclusion: The present study gives scientific evidences that twenty four samples of NTT plants have high free radical scavenging capacity. Strong radical scavenging activity of these plants especially S. quadrifida could be considered as a potential source of natural antioxidants.
Pharmacological activity investigation of Sterculia coccinea Nuzhat Mahbub
2019
Sterculia coccinea plant extract used to assess its different biological activity. Extract was made by soaking the dried plant powder in methanol. After comparing with the standard we found that Methanol extract of the sample gave the activity against all the experimented microbes of ZI (zone of inhibition) against E. coli and B. subtillis. After performing the antioxidant, thrombolytic, antidiarrheal, hypoglycemic and cytotoxic activity assay of methanol extract of sample plant we saw that it has a good biological activity that can be used as a potential traditional medicine.
Triterpenoids and coumarins from the leaves of Sterculia foetida Linn
Science and Technology Development Journal, 2020
Introduction: Sterculia foetida Linn. is widely distributed in tropical countries. As the continuous study on the hexane and ethyl acetate extracts of Sterculia foetida leaves, the isolation and structural determination of four triterpenoids and two coumarins were addressed. Method: The crude extract was prepared from dried power of Sterculia foetida leaves by maceration method in ethanol. This extract was then separated by liquid-liquid partition with n-hexane, chloroform, and ethyl acetate, respectively, to obtain the corresponding extracts. The hexane and ethyl acetate extracts were applied to multiple silica gel column chromatography to yield six compounds. Their chemical structures were determined by the NMR data analysis as well as the comparison their spectroscopic data and physical properties with those of reported literature. Results: Four triterpenoid compounds, including betulinic acid (1), conyzasaponin G (2), taraxerol (3), and taraxer-14-ene- 1a,3b -diol (4), and two c...
TLC profiling and antioxidant activity of phenolic compound from Sterculia oblongata bark extract
Nusantara Bioscience
In the present study, we investigated the total phenolic content and in-vitro antioxidant activity of Sterculia oblongata. Total phenolic content (TPC) of the methanol extract was examined by Folin-Ciocalteu reagent and gallic acid as standard. The in-vitro antioxidant activity was performed by DPPH free radical scavenging activity and βcarotene bleaching assay. The result showed that the TPC of methanol extract was the highest (P<0.05) compared to other extracts. There is a positive and significantly very high Pearson's correlation between antioxidant activity index (AAI) and TPC (r = 0.996). A negative and significantly high Pearson's correlation was obtained between IC50 value and TPC (r =-0.885). The result of β-carotene bleaching assay showed that the rate of the decreased antioxidant activity of S.oblongata extract was lower than that of βcarotene/linoleic acid. The results suggest that the extract of S. oblongata can be used as a natural antioxidant. However, further investigation to isolate and identify the chemical compounds responsible for antioxidant was needed
The Journal of Animal and Plant Sciences, 2020
Genus Sterculia possess various types of compounds which have therapeutic potential. This study was aimed to explore the anticonvulsant, CNS depressant, analgesic, anti-inflammatory and anti-pyretic activities of Sterculia diversifolia stem bark and leaves extracts in mice. The secondary metabolites in MESD (methanolic extract of Sterculia diversifolia) was characterized by UV, IR, 1 H-NMR, 13 C NMR and 2D-NMR spectra in combination with EI-MS spectrometric techniques. Anticonvulsant and CNS depressant effect of MESD was assessed using strychnine-induced convulsion and phenobarbitone-induced hypnotic protocol. Analgesic activity was performed by acetic acid induced writhing and hot plate test while anti-inflammatory and anti-pyretic activities were assessed by carrageenan induced right hind paw edema and brewer's yeast induced pyrexia. The isolation of compounds with different elucidation techniques (1 H-NMR, 13 C NMR and 2D-NMR spectra in combination with EI-MS spectrometric techniques) led to luteolin, isoquercitrin and ursolic acid. The current study results showed that crude MESD significantly (p < 0.05) delayed the onset, shortened the duration and offered protection against strychnine-induced convulsion. Crude MESD significantly (p < 0.05) prolonged the time of phenobarbitone-induced hypnosis. The analgesic response of crude MESD stem bark was more significant as compare to crude MESD leaves, while crude MESD also showed significant anti-inflammatory and antipyretic activity through dose dependent phenomenon. These significant results might be due to flavonoids (luteolin, isoquercitrin) and triterpenoids (ursolic acid) presence, though the involvement of other biologically active secondary metabolites cannot be overlooked.
Sterculia urens: Traditionally important medicinal tree
Journal of Medicinal Plants Studies, 2022
Non Timber Forest Produces (NTFPs) are basic needs and income generation opportunities for forest based tribal communities. Many multipurpose tree species make broad their opportunity from only the single species. Sterculia urensis one of the important NTFPs species having myriads of uses. Gum exudate of this tree is having large market value. This review is to highlight the importance of S. urens to the tribal peoples of India. S. urens can be very important species for tribal communities for food security, medicinal and employments generation for their sustainable livelihood development.
Qualitative Analysis and Biological Screening of Sterculia Tragacantha Fruit Extract
2020
Utilization of natural materials as an alternative medicine in warding off diseases is increasingly in demand. This study aimed to determine the secondary metabolite content, antioxidant activity, antibacterial activity, fatty acid content and amino acid content of the extract of Sterculia tragacantha fruit. Sample was evaluated for phytochemical content, antioxidant activity, antibacterial activity, fatty acid content and amino acids. The results indicated that the phytochemical compounds of papaya woton fruit simplicia include flavonoid, tannin, hydrolyzable tannin, phenolic, polyphenols and saponin. The extract of methanol has a strong antioxidant activity while that of n-hexane has a potential as antibacterial to Vibrio alginolyticus. The main fatty acids of Sterculia tragacantha fruit extract were methyl palmitate and methyl tricosanoate while the main amino acids were L-Arginine, L-Proline and L-Glutamic acid.