A positive role for PEA3 in HER2-mediated breast tumour progression (original) (raw)

Expression of PEA3 and Lack of Correlation Between PEA3 and HER-2/neu Expression in Breast Cancer

Aysegul Sahin

Breast Cancer Research and Treatment, 2006

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The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis

John Hassell, William Muller

Current Biology, 2001

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The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase

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Oncogene, 1998

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Expression of HER2 in Breast Cancer Promotes a Massive Reorganization of Gene Activity and Suggests a Role for Epigenetic Regulation

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Journal of data mining in genomics & proteomics, 2012

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Expression of PEA3/E1AF/ETV4, an Ets-related transcription factor, in breast tumors: positive links to MMP2, NRG1 and CGB expression

Rosette Lidereau

Carcinogenesis, 2003

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Identification and Characterization of PEA3 Ets Subfamily Target Genes in Human Mammary Epithelial Cells

John Hassell

2003

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Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1

Gabrielle Kelly

Journal of Clinical Pathology, 2004

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Biologic and therapeutic role of HER2 in cancer

Elda Tagliabue

Oncogene, 2003

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Expression of HER2 and its association with AP-2 in breast cancer

Anita Naukkarinen

European Journal of Cancer, 2004

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Protein Kinase C Determines HER2 Fate in Breast Carcinoma Cells with HER2 Protein Overexpression without Gene Amplification

Lidia Albano, Elda Tagliabue

Cancer Research, 2007

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ETS genes in breast cancer: A step in the right direction

Saraswati Sukumar

Cancer Biology & Therapy, 2007

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HER2 overexpression in various tumor types, focussing on its relationship to the development of invasive breast cancer

P. Casalini, Elda Tagliabue

Annals of Oncology, 2001

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Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis

John Hassell

Journal of mammary gland biology and neoplasia, 2003

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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

Joaquín Arribas

Oncogene, 2011

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ONCOLOGIA E PATOLOGIA SPERIMENTALE XXIX Ciclo DEVELOPMENT OF PRECLINICAL MODELS OF MAMMARY CARCINOGENESIS: FUNCTIONAL ROLE OF HER2 AND ITS ISOFORMS IN TUMOR PROGRESSION AND IN DRUG RESISTANCE

roberta Laranga

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HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review

Jörgen Carlsson

British journal of cancer, 2004

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Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited

Ruth Lupu

2007

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Expression of the HER 1-4 family of receptor tyrosine kinases in breast cancer. Commentary

William Gullick

Journal of Pathology, 2003

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Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients

Rupert Bartsch

Breast (Edinburgh, Scotland), 2014

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Supplementary Figure 3 from HER3 Is Required for HER2-Induced Preneoplastic Changes to the Breast Epithelium and Tumor Formation

christian young

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PIK3CA, KI67, Estrogen (ER) and Progesterone Receptors (PR) Expression Pattern of in HER2 Positive Breast Cancers

onyekachi onu

Asian Pacific Journal of Cancer Biology

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Expression of the HER1–4 family of receptor tyrosine kinases in breast cancer

Martyn Caplin

The Journal of Pathology, 2003

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A Central Role for HER3 in HER2-Amplified Breast Cancer: Implications for Targeted Therapy

Thinh Pham

Cancer Research, 2008

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Standardized Assessment of the HER2 Status in Breast Cancer by Immunohistochemistry

Linda Schiffhauer

Laboratory Medicine, 2011

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Molecular Analysis of HER2 Signaling in Human Breast Cancer by Functional Protein Pathway Activation Mapping

Lance Liotta

Clinical Cancer Research, 2012

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The HER2 Signaling Network in Breast Cancer-Like a Spider in its Web

Anna-Lena Dittrich

Journal of mammary gland biology and neoplasia, 2014

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HER-2 Signaling in Human Breast Cancer

Kathleen Ignatoski

Breast Cancer - Carcinogenesis, Cell Growth and Signalling Pathways, 2011

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Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer

Alexander Gorelick

Cancer Discovery

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Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ER - breast cancer

Francisco Esteva

Proceedings of the National Academy of Sciences, 2012

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Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer

Synnöve Staff

BMC Cancer

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ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer

Ivana Sestak

Breast Cancer Research, 2012

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Supplementary Figure 2 from HER3 Is Required for HER2-Induced Preneoplastic Changes to the Breast Epithelium and Tumor Formation

christian young

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HER-2 in breast cancer—methods of detection, clinical significance and future prospects for treatment

Sarah Pinder

Critical Reviews in Oncology Hematology, 2002

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A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis

Santiago Ramón y Cajal

Molecular and Cellular Biology, 2009

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