Epidemiological, clinical and therapeutic profile of uterine fibroids at the Befelatanana University hospital centre of obstetric gynecology of Antananarivo, Madagascar (original) (raw)
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Uterine Fibroids In A Tertiary Health Centre South East Nigeria
Nigerian Journal of Medicine, 2008
Background: Uterine fibroids are common benign tumours of the female reproductive tract. This study evaluated the clinical presentations and the treatment of fibroids at Ebonyi State University Teaching Hospital over the 5-year period (2001-2005). Methods: A retrospective analysis of all cases of uterine fibroids admitted into the gynaecological ward of the Ebonyi State University Teaching Hospital (EBSUTH) over the five-year period (2001 2005). Results: Uterine fibroids accounted for 13.6% of all gynaecological admissions during the period. It was found predominantly during the third and fourth decades of life in nulliparas and women of the higher socio economic class. Primary infertility (22.9%), lower abdominal mass (21. 6%), menstrual abnormalities(15.9%), lower abdominal pain (15.9%) and anaemia (11.8%) were the common clinical presentations while abdominal myomectomy was the commonest modality of treatment employed (90%). Conclusion: Uterine fibroid is common among gynaecological admissions in Igbo women of Southeastern Nigeria. Infertility is a common presentation necessitating abdominal myomectomy in majority of the cases.
Open Journal of Obstetrics and Gynecology, 2023
Background: Uterine fibroid is the most common benign gynecological tumor in women of childbearing age and is common in our context. It can be discovered incidentally or by metrorrhagia. Objective: To study the epidemiological, clinical, therapeutic and prognostic aspects of uterine fibroids operated in the gynaecology and obstetrics department of the CHU-T. Patients and Method: This was a descriptive cross-sectional study including all patients operated on for uterine fibromyoma in the gynaecology-obstetrics department. The collection mode was retrospective, over a 5-year period from January 1, 2017 to December 31, 2021 in the mother-child department of the CHU-T. Data entry and analysis were carried out on a microcomputer using Epi info 7.2.5 software. Results: We collected 109 cases of uterine fibroids which represented 42.5% of the surgical activities of the gynaecology department. The average age of the patients was 38.9 years ± 7.8. Married women represented 77.1%. Salaried women accounted for 65.1%. The main reasons for consultation were uterine haemorrhage (53.1%), pelvic pain (40.4%) and hypofertility (31.2%). Ultrasound was performed in all patients to help map the fibroid nuclei. The main indication for surgery was haemorrhagic myoma (43.1%). The surgical treatment was conservative (myomectomy) in 58.7% of cases and radical (hysterectomy) in 27.4% of cases. The most frequent postoperative complication was vulvar haemorrhage and the average hospital stay was 4 days ± 1.4. Anatomical pathological examination of the surgical excision specimen carried out on 30 operated patients concluded that uterine leiomyoma was diagnosed in 100% of cases. Conclusion: Patient education for early detection, universal health insurance and cost subsidies could improve the management of this condition.
Uterine leiomyomata: a five year clinicopathological review in Zaria, Nigeria
Nigerian Journal of Surgical Research, 2006
Background: Uterine Leiomyomata (uterine fibroids) are common gynaecologic conditions affecting mainly women in the reproductive age group. Fibroids are associated with many other distressing gynaecologic conditions like menorrhagia, infertility, lower abdominal swelling and discomfort. Methods: This is a retrospective clinicopathological analysis uterine leiomyomata a five-year period (1996 -2000). The information required was retrieved from histology bench books and request cards. Results: 209 cases were analysed, 62.7% from myomectomy 37.3% following hysterectomy. Younger patients opted for myomectomy possibly in other to allow them complete their family sizes. Uterine fibroids were commoner in the third to fourth decade of life.The nulliparous women to had a higher incidence of uterine fibroid (60.6%) in 71 cases analysed whose parity were known. Lower abdominal swelling is the commonest presenting complaint (48.8%), followed by menorrhagia and infertility accounting for 35.4% and 30.6% respectively. Hyaline degeneration was the commonest degenerative change observed (57.9%). Three cases (1.4%) had necrosis. Nineteen cases were observed to be associated with other co-existing lesions, of which 52.6% occur with fibroid polyps. Adenomyosis accounted for 36.8% and one case each of metastatic carcinoma and interligamentary fibroids. Adequate clinical information and brief surgical procedure on request cards were lacking in most cases. Conclusion: Uterine fibroids are common conditions affecting women in their reproductive age group, which corresponds with economically viable age group. This condition is associated with significant morbity and attention needs to be focused on it.
Age of first diagnosis and incidence rate of uterine fibroids in Ghana. A retrospective cohort study
PLOS ONE
Background Uterine fibroids are benign tumors that grow in or on the uterus of women. Globally, they occur in more than 80% of women of African ancestry and 70% in white women. Uterine fibroid requires much attention because of its high incidence rate among women of all races and ages. This study sought to document the age of first diagnosis and incidence rates of uterine fibroids in our urban setting. Methods This study reviewed and analyzed the ages and year of diagnosis of all 2,469 patients with the first diagnosis of uterine fibroids from 1st January 2018 to 31st December 2021 in South-Central Ghana. The obtained data were analyzed using GNU PSPP, Python on Jupyter Notebook and Libre Office Calc with statistical significance level set at p≤0.05. Results The overall average age was 36.29±8.08 years, with age range 17–61 years and the age groups with the highest frequencies were 35–39 years (n = 642, 26.00%), 30–34 years (n = 563, 22.80%) and 40–44 years (n = 381, 15.43%). The me...
Prevalence and Incidence of Uterine Fibroid at King Abdulaziz University Hospital Saudi Arabia
Clinical Medicine and Diagnostics, 2016
Aim of the work: Extensive study has been made to get specific ratio of the women who had uterine fibroid and the total range of incidence of the leiomyoma. Methods and Material: Retrospective study of (1111) women patients referred from obstetrics and gynecology clinics (Women’s’ age between 15 and 79 years, mean was 52yrs). Data was collected from January 2013 to December 2014 at the Hospital of king Abdulaziz University. Results: A total of 236(21.2%) of 1111 patients were cases of uterine fibroid, while the remaining 875(78.8%) cases had normal ultrasound findings. According to the clinical symptoms that related to fibroid, bleeding which included 65(27.5%) was the commonest symptom for the patient’s then abdominal pain 32(13.6%). The 123(52%) of the women presented with solitary fibroids and 113(48%) women with multiple leiomyomata. Conclusions: Uterine fibroid highly related with reproductive age by (56.3%) and this result is matching to the result published in previous studies.
BMC Research Notes
Objectives: Uterine fibroids are common among the black race and associated with adverse outcomes in pregnancy. The aim of this study was to determine the prevalence, clinical presentation and maternal and foetal outcomes of birth among pregnant women with leiomyoma in two secondary care hospitals in Limbe and Buea, Cameroon. Results: The prevalence of fibroid in pregnancy was 16.7%. Respondents with leiomyoma were older than those without (p < 0.001) and of low parity (p = 0.02). Acute abdominal pain, (OR 3.8; 95% CI 1.4-9.9, p = 0.007), vaginal bleeding (OR 5.2; 95% CI 1.6-16.3, p = 0.004) were clinical presentation of leiomyoma in pregnancy. Cesarean birth (OR 4.5; 95% CI 1.4-13.6, p = 0.008), low Apgar score, (OR 6.0; 95% CI 1.9-19.1, p = 0.002), and postpartum hemorrhage (OR 4.7; 95% CI 1.7-13.2, p = 0.003) were adverse outcomes recorded.
Obstetrics Gynecology and Reproductive Sciences, 2021
Objectives: To calculate the frequency of uterine fibromyomas, to describe the epidemiological profile, to describe the management and to establish the prognosis of women with uterine fibromyomas in the gynaecology-obstetrics department of the Regional Hospital of Labé. Methodology: This was a retrospective descriptive study lasting three (3) years from 1 January 2017 to 31 December 2019. All patients admitted and operated on in the department for uterine fibromyomas during the study period were included. Patients who were not operated for uterine fibromyomas in the department and incomplete records were not included. Our data were collected and analysed using Epi-Info software version 7.2.2.6. Word, Excel and Power point software from Pack office 2016 were used for data entry and presentation. The study involved a continuous series of 115 anaemic pregnant women. We proceeded with an exhaustive recruitment of pregnant women according to the criteria defined above. Results: The frequ...
Surgical Management of Uterine Fibroids in Makurdi, Nigeria
IOSR Journals , 2019
Uterine leiomyomas are the commonest benign tumours of the female genital tract, occurring in young women of reproductive age. Treatment modalities, in our setting, are mainly surgical. The aim was to determine the incidence, patterns of presentation and appraise the intra and post-operative morbidities associated with the surgical methods of management. A retrospective review of surgically managed cases of uterine fibroids over a five-year period from September, 2002-August, 2007 was carried out at the Federal Medical Centre, Makurdi, Nigeria. Data was obtained from the medical records department, gynaecology ward admissions and theatre registers. Statistical analysis was performed using SPSS for windows version 16 and significance was set at P-value of < 0.05%. One hundred and thirty one cases of uterine fibroids were reviewed. They constituted 8.4% and 14.9% of new gynaecological admissions and surgeries respectively. Uterine fibroids were commoner amongst nulliparous or low parity women, namely para 0-2, 116 (88.5%) and within the 3 rd and 4 th decades of life 108 (82.4%). Majority of patients had abdominal swelling 58.8%, and menorrhagia 52.7%. Surgical treatment was the major mode of management of the condition, with myomectomy accounting for 84.0% and hysterectomy 16.0% of the cases. Pyrexia (26.0%), anaemia (19.8%), and prolonged hospital stay (16.0%) constituted the major post-operative morbidities. Uterine fibroids are a major gynaecological condition among women of low parity in the third and fourth decade of life in Makurdi. Surgery was the mainstay of management. The post operative morbidities were pyrexia, anaemia, and occasionally prolonged hospital stay.
Uterine fibroids — Causes, impact, treatment, and lens to the African perspective
Frontiers in Pharmacology
Leiomyomas, or uterine fibroids as they are commonly known, are mostly seen in women of reproductive age. However, they can go undetected in most women, and approximately 25% of women show clinical symptoms. Although fibroids are a global burden impacting 80% of premenopausal women, they are more prevalent among Black women than among women of other races. Based on clinical diagnosis, the estimated cumulative incidence of fibroids in women ≤50 years old is significantly higher for black (>80%) versus white women (∼70%). The cause of leiomyomas is not clearly known, but studies have shown evidence of factors that drive the development or exacerbation of the disease. Evidence has linked risk factors such as lifestyle, age, environment, family history of uterine fibroids, and vitamin D deficiencies to an increased risk of uterine fibroids, which impact women of African descent at higher rates. Treatments may be invasive, such as hysterectomy and myomectomy, or non-invasive, such as ...
Exploring uterine fibroids and its treatment in current scenario
IP International Journal of Comprehensive and Advanced Pharmacology
Uterine Fibroids (leiomyoma) are made of muscle cells and other grow tissues grow in and around of the wall of the uterus. Uterine fibroids benign tumors in women reproduction age worldwide. Many are discovered incidentally on clinically examination. Approximately 30% of women with uterine fibroids will present with severe symptoms, which can include abdominal uterine bleeding, anemia, pelvic pain and constipation. Infertility and recurrent miscarriage may also be symptoms of fibroids, depending on their location and size, especially for sub mucous and intramural myelomas distorting the uterine cavity. Current option for symptomatic fibroid treatment includes expectant medical and surgical management radiology procedures. Ultrasound can be done, when a patient is symptomatic of uterine fibroids. Fibroids are generally classified by their location; intramural fibroids, subserosal fibroids, submucosal fibroids. The cause of uterine fibroids is unknown, But research and clinical experi...