IgG-mediated immune suppression in mice is epitope specific except during high epitope density conditions (original) (raw)

IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors

Birgitta Heyman

PloS one, 2015

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IgG‐mediated suppression of antibody responses: Hiding or snatching epitopes?

Birgitta Heyman

2020

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Epitope-Specific Suppression of IgG Responses by Passively Administered Specific IgG: Evidence of Epitope Masking

Birgitta Heyman

Frontiers in immunology, 2017

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Efficient IgG-mediated suppression of primary antibody responses in Fcγ receptor-deficient mice

Teresita de Ståhl

Proceedings of the National Academy of Sciences, 1999

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IgG Suppresses Antibody Responses to Sheep Red Blood Cells in Double Knock-Out Mice Lacking Complement Factor C3 and Activating Fcγ-Receptors

Birgitta Heyman

Frontiers in Immunology, 2020

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Fc-Dependent IgG-Mediated Suppression of the Antibody Response: Fact or Artefact?

Birgitta Heyman

Scandinavian Journal of Immunology, 1990

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Dual Immunoregulatory Effects of Monoclonal IgG-Antibodies: Suppression and Enhancement of the Antibody Response

Birgitta Heyman

Scandinavian Journal of Immunology, 1989

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Fc RIIB in IgG-Mediated Suppression of Antibody Responses: Different Impact In Vivo and In Vitro

Birgitta Heyman

The Journal of Immunology, 2001

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Complement activation is not required for IgG-mediated suppression of the antibody response

Birgitta Heyman

European Journal of Immunology, 1988

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Section 1C: Assessment of the functional activity and IgG Fc receptor utilisation of 64 IgG Rh monoclonal antibodies. Coordinator’s report

Peter Ligthart

Transfusion Clinique et Biologique, 2002

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IgG-effector functions: “The Good, The Bad and The Ugly”

Gestur Vidarsson

Immunology Letters, 2014

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Complement Receptors 1 and 2 in Murine Antibody Responses to IgM-Complexed and Uncomplexed Sheep Erythrocytes

Frida Johnson, Jenny Martinsson

PLoS ONE, 2012

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Immunoregulation by monoclonal sheep erythrocyte-specific IgG antibodies: suppression is correlated to level of antigen binding and not to isotype

Birgitta Heyman

The Journal of Immunology

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Clearance of Human IgG1-Sensitised Red Blood Cells In Vivo in Humans Relates to the In Vitro Properties of Antibodies from Alternative Cell Lines

Mike Clark

PLoS ONE, 2014

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Hyperacute Rejection by Anti-Gal IgG1, IgG2a, and IgG2b Is Dependent on Complement and Fc- Receptors

Sjef Verbeek

The Journal of Immunology, 2008

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The Ligands for Human IgG and Their Effector Functions

Gestur Vidarsson

Antibodies

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Stuart, S. G. et al. Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium. EMBO J. 8, 3657-3666

Neil Simister

The EMBO Journal

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IgG-Mediated Enhancement of Antibody Responses Is Low in Fc Receptor γ Chain-Deficient Mice and Increased in FcγRII-Deficient Mice

Sjef Verbeek

The Journal of Immunology, 1999

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IgM-mediated enhancement of in vivo anti-sheep erythrocyte antibody responses: Isotype analysis of the enhanced responses

Birgitta Heyman

Cellular Immunology, 1985

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Mice Immunized with IgG Anti-Sheep Red Blood Cells (SRBC) Together With SRBC Have a Suppressed Anti-SRBC Antibody Response but Generate Germinal Centers and Anti-IgG Antibodies in Response to the Passively Administered IgG

Birgitta Heyman

Frontiers in Immunology, 2017

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Specific IgM and Regulation of Antibody Responses

Birgitta Heyman

Current Topics in Microbiology and Immunology, 2017

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IgG-mediated immunosuppression is not dependent on erythrocyte clearance or immunological evasion: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the newborn?

Alan Lazarus

British Journal of Haematology, 2007

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Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium

Neil Simister

The EMBO Journal, 1989

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Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (Fc R)

Hiromi Kubagawa

Proceedings of the National Academy of Sciences, 2012

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IgE-mediated enhancement of antibody responses: the beneficial function of IgE?

Birgitta Heyman

Allergy, 2002

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Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

Werner Muller

Proceedings of the National Academy of Sciences, 2009

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IgG subclasses and allotypes: from structure to effector functions

Gestur Vidarsson

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Antigen specificity determines anti-red blood cell IgG-Fc alloantibody glycosylation and thereby severity of haemolytic disease of the fetus and newborn

Peter Ligthart

British Journal of Haematology

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All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes

peter ralph

The Journal of Immunology

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IgG Fe receptors that resemble class I major histocompatibility complex antigens

Neil Simister

Biochemical Society Transactions, 1993

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IgG3-Mediated Enhancement of the Antibody Response is Normal in FcgammaRI-Deficient Mice

Sjef Verbeek

Scandinavian Journal of Immunology, 2005

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The IgG Subclass Pattern of Complement Activation Depends on Epitope Density and Antibody and Complement Concentration

T. Michaelsen

Scandinavian Journal of Immunology, 1989

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Low-affinity FcγR interactions can decide the fate of novel human IgG-sensitised red blood cells and platelets

Mike Clark

European Journal of Immunology, 2014

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Impact of a Three Amino Acid Deletion in the CH2 Domain of Murine IgG1 on Fc-Associated Effector Functions

Falk Nimmerjahn

The Journal of Immunology, 2008

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