Section 1C: Assessment of the functional activity and IgG Fc receptor utilisation of 64 IgG Rh monoclonal antibodies. Coordinator’s report (original) (raw)

Clearance of Human IgG1-Sensitised Red Blood Cells In Vivo in Humans Relates to the In Vitro Properties of Antibodies from Alternative Cell Lines

Mike Clark

PLoS ONE, 2014

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All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes

peter ralph

The Journal of Immunology

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Binding and endocytosis of erythrocytes sensitized with rabbit IgG via Fcγ receptors of human monocytes

Edit Gyimesi

Immunology

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Development of an Immunoassay for the Detection of Minute Amounts of IgG-Coated Erythrocytes in Whole Blood and Its Application for the Assessment of Fc-Mediated Clearance of Anti-D-Coated Erythrocytes in vivo

Lars Lööf

Vox Sanguinis, 1989

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Multifactorial aspects of antibody-mediated blood cell destruction

Peter Ligthart

2014

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The use of anti-IgG monoclonal antibodies in mapping the monocyte receptor site on IgG

J. Woof

Molecular Immunology, 1986

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IgG-mediated immunosuppression is not dependent on erythrocyte clearance or immunological evasion: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the newborn?

Alan Lazarus

British Journal of Haematology, 2007

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Low-affinity FcγR interactions can decide the fate of novel human IgG-sensitised red blood cells and platelets

Mike Clark

European Journal of Immunology, 2014

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Fc-Dependent IgG-Mediated Suppression of the Antibody Response: Fact or Artefact?

Birgitta Heyman

Scandinavian Journal of Immunology, 1990

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Heterogeneity of IgG1 monoclonal anti-Rh(D): an investigation using ADCC and macrophage binding assays

Marcela Contreras

British Journal of Haematology, 1987

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A human anti-D monoclonal antibody selected for enhanced FcγRIII engagement clears RhD + autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies

Jean-francois Prost

British Journal of Haematology, 2008

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Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils

Harvey Cohen, H. Fleit

Journal of Experimental Medicine, 1986

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Red cell Fc receptors and their participation in the passive haemagglutination mediated by non precipitating antibodies

Silvia Hajos

Immunology

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Dual Immunoregulatory Effects of Monoclonal IgG-Antibodies: Suppression and Enhancement of the Antibody Response

Birgitta Heyman

Scandinavian Journal of Immunology, 1989

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Inhibition of Fc R-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and Fc RIIb in human macrophages

Iwan Kustiawan, Gestur Vidarsson

Blood, 2014

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Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fcγ receptor

Gabriella Sarmay

Molecular Immunology, 1992

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Functional in vitro studies of recombinant human immunoglobulin�G and immunoglobulin�A anti-D

Leif Nielsen

Transfusion, 2007

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Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies

HERMAN WALDMANN

Journal of Experimental Medicine, 1987

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The specificity of the Fc receptor on murine lymphocytes for immunoglobulins of the IgG and IgM classes

Ranjan Ramasamy

Immunology

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Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions

Raymond Dwek

Journal of Molecular Biology, 2012

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IgG Suppresses Antibody Responses to Sheep Red Blood Cells in Double Knock-Out Mice Lacking Complement Factor C3 and Activating Fcγ-Receptors

Birgitta Heyman

Frontiers in Immunology, 2020

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Bispecific anti-human red blood Rhesus-D antigen × anti FcγRI targeted antibody-dependent cell-mediated cytotoxicity and phagocytosis by mononuclear leucocytes

Jean-Loup Romet-Lemonne

Clinical and Experimental Immunology, 2008

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Dichotomous effect of monocyte Fc receptor interaction on anti-CD3-induced immunoglobulin synthesis

W. Pichler

Cellular Immunology, 1990

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Monomeric IgG in intravenous Ig preparations is a functional antagonist of FcγRII and FcγRIIIb

Wim Bleeker

The Journal of …, 2004

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Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc RI, in the presence of monomeric IgG

Jeanette Leusen

Blood, 2010

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Cytotoxicity mediated by human Fc receptors for IgG

Paul Guyre

Immunology Today, 1989

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Comparison of the cytophilic activities of guinea pig IgG1 and IgG2 antibodies

Bob Leslie

European Journal of Immunology, 1976

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Differential Contribution of Three Activating IgG Fc Receptors (Fc RI, Fc RIII, and Fc RIV) to IgG2a- and IgG2b-Induced Autoimmune Hemolytic Anemia in Mice

Falk Nimmerjahn

The Journal of Immunology, 2008

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IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors

Birgitta Heyman

PloS one, 2015

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Polymorphonuclear leukocyte function triggered through the high affinity Fc receptor for monomeric IgG

Paul Guyre

Journal of Immunology, 1987

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The Binding of Human IgG to Minipig FcγRs – Implications for Preclinical Assessment of Therapeutic Antibodies

Tilman Schlothauer

Pharmaceutical Research, 2019

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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy

Radka Saldova

Scientific Reports

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Subclass specificity of the Fc receptor for human IgG on K562*1

Giuseppe Teti

Cellular Immunology, 1988

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Binding of immunoglobulin G to peripheral blood lymphocytes

KRISHNAN HAJELA

Immunology Letters, 1988

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IgG-Fc-receptors: ligand binding and lysis induction

Gabriella Sarmay

Immunology Letters, 1989

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