Section 1C: Assessment of the functional activity and IgG Fc receptor utilisation of 64 IgG Rh monoclonal antibodies. Coordinator’s report (original ) (raw )Clearance of Human IgG1-Sensitised Red Blood Cells In Vivo in Humans Relates to the In Vitro Properties of Antibodies from Alternative Cell Lines
Mike Clark
PLoS ONE, 2014
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All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes
peter ralph
The Journal of Immunology
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Binding and endocytosis of erythrocytes sensitized with rabbit IgG via Fcγ receptors of human monocytes
Edit Gyimesi
Immunology
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Development of an Immunoassay for the Detection of Minute Amounts of IgG-Coated Erythrocytes in Whole Blood and Its Application for the Assessment of Fc-Mediated Clearance of Anti-D-Coated Erythrocytes in vivo
Lars Lööf
Vox Sanguinis, 1989
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Multifactorial aspects of antibody-mediated blood cell destruction
Peter Ligthart
2014
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The use of anti-IgG monoclonal antibodies in mapping the monocyte receptor site on IgG
J. Woof
Molecular Immunology, 1986
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IgG-mediated immunosuppression is not dependent on erythrocyte clearance or immunological evasion: implications for the mechanism of action of anti-D in the prevention of haemolytic disease of the newborn?
Alan Lazarus
British Journal of Haematology, 2007
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Low-affinity FcγR interactions can decide the fate of novel human IgG-sensitised red blood cells and platelets
Mike Clark
European Journal of Immunology, 2014
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Fc-Dependent IgG-Mediated Suppression of the Antibody Response: Fact or Artefact?
Birgitta Heyman
Scandinavian Journal of Immunology, 1990
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Heterogeneity of IgG1 monoclonal anti-Rh(D): an investigation using ADCC and macrophage binding assays
Marcela Contreras
British Journal of Haematology, 1987
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A human anti-D monoclonal antibody selected for enhanced FcγRIII engagement clears RhD + autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies
Jean-francois Prost
British Journal of Haematology, 2008
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Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils
Harvey Cohen , H. Fleit
Journal of Experimental Medicine, 1986
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Red cell Fc receptors and their participation in the passive haemagglutination mediated by non precipitating antibodies
Silvia Hajos
Immunology
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Dual Immunoregulatory Effects of Monoclonal IgG-Antibodies: Suppression and Enhancement of the Antibody Response
Birgitta Heyman
Scandinavian Journal of Immunology, 1989
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Inhibition of Fc R-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and Fc RIIb in human macrophages
Iwan Kustiawan , Gestur Vidarsson
Blood, 2014
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Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fcγ receptor
Gabriella Sarmay
Molecular Immunology, 1992
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Functional in vitro studies of recombinant human immunoglobulin�G and immunoglobulin�A anti-D
Leif Nielsen
Transfusion, 2007
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Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies
HERMAN WALDMANN
Journal of Experimental Medicine, 1987
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The specificity of the Fc receptor on murine lymphocytes for immunoglobulins of the IgG and IgM classes
Ranjan Ramasamy
Immunology
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Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions
Raymond Dwek
Journal of Molecular Biology, 2012
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IgG Suppresses Antibody Responses to Sheep Red Blood Cells in Double Knock-Out Mice Lacking Complement Factor C3 and Activating Fcγ-Receptors
Birgitta Heyman
Frontiers in Immunology, 2020
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Bispecific anti-human red blood Rhesus-D antigen × anti FcγRI targeted antibody-dependent cell-mediated cytotoxicity and phagocytosis by mononuclear leucocytes
Jean-Loup Romet-Lemonne
Clinical and Experimental Immunology, 2008
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Dichotomous effect of monocyte Fc receptor interaction on anti-CD3-induced immunoglobulin synthesis
W. Pichler
Cellular Immunology, 1990
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Monomeric IgG in intravenous Ig preparations is a functional antagonist of FcγRII and FcγRIIIb
Wim Bleeker
The Journal of …, 2004
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Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc RI, in the presence of monomeric IgG
Jeanette Leusen
Blood, 2010
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Cytotoxicity mediated by human Fc receptors for IgG
Paul Guyre
Immunology Today, 1989
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Comparison of the cytophilic activities of guinea pig IgG1 and IgG2 antibodies
Bob Leslie
European Journal of Immunology, 1976
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Differential Contribution of Three Activating IgG Fc Receptors (Fc RI, Fc RIII, and Fc RIV) to IgG2a- and IgG2b-Induced Autoimmune Hemolytic Anemia in Mice
Falk Nimmerjahn
The Journal of Immunology, 2008
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IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors
Birgitta Heyman
PloS one, 2015
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Polymorphonuclear leukocyte function triggered through the high affinity Fc receptor for monomeric IgG
Paul Guyre
Journal of Immunology, 1987
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The Binding of Human IgG to Minipig FcγRs – Implications for Preclinical Assessment of Therapeutic Antibodies
Tilman Schlothauer
Pharmaceutical Research, 2019
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Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy
Radka Saldova
Scientific Reports
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Subclass specificity of the Fc receptor for human IgG on K562*1
Giuseppe Teti
Cellular Immunology, 1988
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Binding of immunoglobulin G to peripheral blood lymphocytes
KRISHNAN HAJELA
Immunology Letters, 1988
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IgG-Fc-receptors: ligand binding and lysis induction
Gabriella Sarmay
Immunology Letters, 1989
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