The Na+/Ca2+ exchanger inhibitor KB-R7943 activates large-conductance Ca2+-activated K+ channels in endothelial and vascular smooth muscle cells (original) (raw)

Single-Channel Characterization of the Pharmacological Properties of the K(Ca 2+ ) Channel of Intermediate Conductance in Bovine Aortic Endothelial Cells

Remy Sauve

Journal of Membrane Biology, 1998

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In Situ Characterization of the Ca2+ Sensitivity of Large Conductance Ca2+-Activated K+ Channels: Implications for Their Use as Near-Membrane Ca2+ Indicators in Smooth Muscle Cells

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Biophysical Journal, 1998

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Vincent Groppi

The Journal of Membrane Biology, 1994

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An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Carlota Abella

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High-conductance Ca2+-activated K+ channels: Pharmacology and molecular characterization

G. Kaczorowski

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Philip Langton

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Ion channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle

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High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943

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Mechanisms of Cs+ blockade in a Ca2+-activated K+ channel from smooth muscle

Osvaldo Alvarez

Biophysical Journal, 1987

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Cecilia Vergara

Current Opinion in Neurobiology, 1998

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Trafficking of Intermediate (KCa3.1) and Small (KCa2.x) Conductance, Ca 2+ -Activated K + Channels: a Novel Target for Medicinal Chemistry Efforts?

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ChemMedChem, 2012

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Activation of BK channels in rat chromaffin cells requires summation of Ca(2+) influx from multiple Ca(2+) channels

Murali Prakriya

Journal of neurophysiology, 2000

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Potassium Channels and Membrane Potential in the Modulation of Intracellular Calcium in Vascular Endothelial Cells

David J Adams

Journal of Cardiovascular Electrophysiology, 2004

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