Prediction and Experimental Validation of Novel STAT3 Target Genes in Human Cancer Cells (original) (raw)
Genome-wide discovery of functional transcription factor binding sites by comparative genomics: The case of Stat3
Emanuela Pupo
Proceedings of The National Academy of Sciences, 2009
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Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors
Mohammad Aziz
Cancer Biology & Therapy, 2011
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Impact of the N-terminal domain of STAT3 in STAT3-dependent transcriptional activity
Jaison Jacob
Molecular and cellular biology, 2015
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Identification of Human STAT5-dependent Gene Regulatory Elements Based on Interspecies Homology
Sarah Walker
Journal of Biological Chemistry, 2006
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QUICK identification and SPR validation of signal transducers and activators of transcription 3 (Stat3) interacting proteins
Chongyang Li
Journal of Proteomics, 2012
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Methods Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic
Akshay Bhinge
2007
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Genome-wide analysis of STAT target genes: Elucidating the mechanism of STAT-mediated oncogenesis
James James Alvarez
Cancer Biology & Therapy, 2004
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Identification of Novel STAT3 Target Genes Associated with Oncogenesis
Rachel Haviland
2011
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Isolation of Unique STAT5 Targets by Chromatin Immunoprecipitation-based Gene Identification
David Frank
Journal of Biological Chemistry, 2004
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Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein
Patrick Gunning
ChemMedChem, 2008
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CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3
David Frank
Neoplasia, 2020
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The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions
Eleni Katsantoni
Nucleic Acids Research, 2016
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Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells
Jakub Mieczkowski, Bozena Kaminska
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2014
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Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
Joel Drewry
… and Cell Biology, 2009
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Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
Thomas Zeng
Nature Methods, 2007
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STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain
Anatoly Dritschilo
Proceedings of the National Academy of Sciences, 2013
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A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites
Christoph Herrmann-Lingen
PloS one, 2014
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The Sin3a repressor complex is a master regulator of STAT transcriptional activity
Judith Verhelst
Proceedings of the National Academy of Sciences, 2012
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TrFAST: A Tool to Predict Signaling Pathway-specific Transcription Factor Binding Sites
Muhammad Sulaman Nawaz
Genomics, Proteomics & Bioinformatics, 2012
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STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
Leo Koenderman
The Journal of biological chemistry, 1996
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STAT proteins: novel molecular targets for cancer drug discovery
James Turkson
Oncogene, 2000
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The Biological Functions of the Versatile Transcription Factors STAT3 and STAT5 and New Strategies for their Targeted Inhibition
Itamar Barash
Journal of Mammary Gland Biology and Neoplasia, 2006
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The STAT3 oncogene as a predictive marker of drug resistance
Igor Roninson
Trends in Molecular Medicine, 2007
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