Idiopathic Calcinosis Cutis of Hip: A Case Report and Review of Literature (original) (raw)
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Calcinosis Cutis of the Thigh: A Surgeon's Perspective and Recent Advances
Zenodo (CERN European Organization for Nuclear Research), 2022
Calcinosis cutis is a clinical condition in which calcium salts are deposited in the skin and subcutaneous tissue. It is classified into four major types-dystrophic, metastatic, iatrogenic and idiopathic. Clinically, non-specific skin nodules to cutaneous swellings are seen. Diagnosis of calcinosis cutis is difficult alone and the need for ancillary techniques likes histological examination, laboratory techniques to determine metabolic abnormalities and radiological examination including plain X-ray, CT scanning to demonstrate the extent of tissue calcification. We report a 72 year old female who presented with a painless swelling over the right thigh since 2 years. Biopsy revealed calcinosis cutis. Radiological imaging was suggestive of a lesion confined to the skin. We report a case of calcinosis cutis of the thigh with relevant discussion on the same. Calcinosis cutis of the thigh is a rare clinical entity with only a handful of cases reported till date. In this case report, we discuss about calcinosis cutis and throw light on the various types, clinical presentation, diagnosis and management of the same.
Unusually diffuse idiopathic calcinosis cutis
Clinical Rheumatology, 2006
Calcifications in idiopathic calcinosis cutis are most commonly localized to one area. We herein report a 66-year-old woman with idiopathic calcinosis cutis who unusually exhibited widespread calcific deposits. In this report, we will also briefly discuss the pathogenesis, differential diagnosis, and current treatment of this disease.
Clinicopathological study of 6 cases of idiopathic calcinosis cutis: A case series
Indian Journal of Pathology and Oncology
Calcinosis cutis is a rare, benign and usually asymptomatic condition which may involve any part of skin. Characterized histologically by deposition of calcium within the dermis. Can present at variable site with variable pathogenesis. This case series present the rare entity of idiopathic cutaneous calcinosis which can be diagnosed accurately with clinical, pathological and metabolic correlation, is completely curable by surgical excision and has an excellent prognosis.
https://www.ijhsr.org/IJHSR\_Vol.7\_Issue.4\_April2017/IJHSR\_Abstract.073.html, 2017
Calcinosis cutis is a rare soft tissue lesion characterized by the deposition of calcium salts. There are varied clinical settings attributed to calcium deposition and these can be subjected to fine-needle aspiration (FNA). Since cutaneous calcific deposits may clinically mimic a tumor, it is advisable to diagnose them by FNA cytology (FNAC) which is a rapid, reliable and simple procedure. Were ported three cases of idiopathic calcinosis cutis by FNA. Cytological finding of amorphous granular material consistent with calcium salts and the appropriate clinical background led to the cytodiagnosis of idiopathic calcinosis cutis further confirmed by special stains on cytosmears in all the three cases. Points of concern for a correct interpretation of the cytological findings along with review of literature are also discussed.
Calcinosis Cutis: A Rare Case Report
Journal of Evidence Based Medicine and Healthcare, 2015
Calcinosis cutis is a condition of accumulation of calcium salts within the dermis. We are presenting a case of calcinosis cutis occurring in healthy individuals, with normal serum calcium and phosphorus levels.
Calcinosis universalis: a rare diagnosis
Journal of Pediatric Orthopaedics B, 2005
Calcinosis universalis is characterized by the deposit of calcium salts in skin, subcutaneous tissue, tendons and muscles. Most cases become apparent during the first decade of life. Clinical aspects may vary from arthralgia to movement limitation, with calcification of soft tissues. Differential diagnosis should exclude fibrodysplasia ossificans progressive, progressive osseous heterodysplasia, myositis ossificans and dermatopolymyositis. There is no specific treatment, but the use of calcium chelates (EDTA), biphosphonates (disodium etidronate) and steroids are mentioned. This paper presents a review of the literature and adds a new case of calcinosis universalis and its evolution in 28 months, describing laboratory and radiograph findings and suggesting the differential diagnosis among processes of soft tissue calcification.
Idiopathic calcinosis cutis of the right iliac region: Common lesion at uncommon
Indian Journal of Case Reports, 2022
Calcinosis cutis is an uncommon soft tissue lesion characterized by the deposition of calcium salts in the skin or subcutaneous tissue attributed to a wide variety of causes. We present a case of idiopathic calcinosis cutis in an adult male, who presented with a swelling in the right iliac region. Chalky white aspirate and amorphous basophilic granular material on microscopy suggestive of calcium deposits were noted. Histopathological examination of the excised mass coupled with appropriate clinical background led to the final diagnosis of idiopathic calcinosis cutis. We present this case with a complete diagnostic workup to undermine the importance of considering this lesion in the differential diagnoses of a subcutaneous hard lump in an otherwise healthy patient.
Calcinosis Cutis of the Hand in a Renal Failure Patient: A Case Report
Journal of Orthopaedic Surgery, 2011
A 25-year-old woman with end-stage renal failure presented with subcutaneous calcinosis cutis that grew rapidly in both hands. Radiographs showed subcutaneous lobulated calcific deposits. Magnetic resonance imaging revealed a heterogeneous mass encasing segments of the abductor pollicis longus and extensor pollicis brevis tendons. Excision of the masses was performed. Histopathology revealed amorphous calcified deposits in fibrous tissue and a foreign body reaction. There was no evidence of a tubercular lesion. Further investigation revealed the presence of hyperphosphataemia and secondary hyperparathyroidism, despite a normal serum calcium level. Oral phosphate-lowering agents failed to control the condition, and recurrence was noted 6 months later. The patient finally underwent parathyroidectomy and has had no further recurrence.
Calcinosis cutis: A rare feature of adult dermatomyositis
European Journal of Internal Medicine, 2013
Dermatomyositis is an idiopathic inflammatory myopathy with characteristic cutaneous manifestations. We describe a case of a 55year-old woman with dermatomyositis who presented with dystrophic calcinosis resistant to medical treatment. Dermatomyositis is an idiopathic inflammatory myopathy with characteristic cutaneous manifestations, including heliotrope rash, Gottron papules, periungual telangiectasias, photodistributed erythema, poikiloderma, and alopecia. Although heliotrope rash and Gottron papules are specific cutaneous features, calcinosis of the skin or muscles is unusual in adults with dermatomyositis. However, it may occur in up to 40 percent of children or adolescents [1]. Calcinosis cutis is the deposition of insoluble calcium salts in the skin. Calcinosis cutis may be divided into four categories according to the pathogenesis as follows: dystrophic, metastatic, idiopathic, and iatrogenic. In connective tissue diseases, calcinosis is mostly of the dystrophic type and it seems to be a localized process rather than an imbalance of calcium homeostasis. Calcium deposits may be intracutaneous, subcutaneous, fascial, or intramuscular. Clinical synopsis A 55-year-old woman was referred for evaluation because of multiple, firm nodules of the lateral hips since 1994. At that time, dermatomyositis was diagnosed based on cutaneous, muscular and pulmonary involvement. The nodules, gradually enlarging since 1999, have begun to cause incapacitation pain and many exude a yellowish material suggestive of calcium. She denied an inciting traumatic event. Combinations of oral prednisone, hydroxychloroquine, or chloroquine, have been able to control the heliotrope rash, Gottron papules, and myositis, but have not prevented progression of nodule formation. Physical examination revealed multiple, firm, erythematous, whitish nodules, some of which exuded a chalky white material. They were located on the face, arms, and lateral hips; the largest were more than 6 cm in diameter (Fig. 1).
“Milk of calcium”: a rare presentation of calcinosis1
Revista brasileira de reumatologia, 2014
Rheumatic diseases such as juvenile dermatomyositis (JDM), juvenile sistemic lupus erythematosus (JSLE) and sistemic sclerosis may have calcium deposits in the subcutaneous and muscle tissues known as calcinosis. Extensive calcium-laden fl uid collections referred as "milk of calcium" are rare forms of calcinosis in JDM. We describe a 15-year old patient with overlap syndrome (sclerodermatomyositis and JSLE), whose magnetic resonance imaging (MRI) showed perimusculares fl uid collections in the lower limbs. During surgery, we observed the presence of whitish fl uid collection suggestive of "milk of calcium".