New dioxaborolane chemistry enables [18F]-positron-emitting, fluorescent [18F]-multimodality biomolecule generation from the solid-phase (original) (raw)

Design, Synthesis, and Characterization of a Dual Modality Positron Emission Tomography and Fluorescence Imaging Agent for Monoclonal Antibody Tumor-Targeted …

Ranjan Banerjee

J. Med. …, 2007

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Toward preparation of antibody-based imaging probe libraries for dual-modality positron emission tomography and fluorescence imaging

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Prostate Cancer PET Bioprobes: Synthesis of [18F]-Radiolabeled Hydroxyflutamide Derivatives

Michael Gozin

Bioorganic & medicinal …, 2005

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Arylfluoroborates and Alkylfluorosilicates as Potential PET Imaging Agents: High-Yielding Aqueous Biomolecular 18 F-Labeling

Thomas Ruth

Journal of the American Chemical Society, 2005

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Dual mode fluorescent (18)F-PET tracers: efficient modular synthesis of rhodamine-[cRGD]2-[(18)F]-organotrifluoroborate, rapid, and high yielding one-step (18)F-labeling at high specific activity, and correlated in vivo PET imaging and ex vivo fluorescence

Donald Yapp

Bioconjugate chemistry, 2014

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One-step and one-pot-two-step radiosynthesis of cyclo-RGD-(18)F-aryltrifluoroborate conjugates for functional imaging

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American journal of nuclear medicine and molecular imaging, 2013

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Design, Synthesis, and Preliminary in Vitro and in Vivo Evaluation of N -(2-diethylaminoethyl)-4-[ 18 F]fluorobenzamide ([ 18 F]-DAFBA): A Novel Potential PET Probe to Image Melanoma Tumors

Aniruddha Doke

Bioconjugate Chemistry, 2009

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An organotrifluoroborate for broadly applicable one-step 18F-labeling

Donald Yapp

Angewandte Chemie (International ed. in English), 2014

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Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Nic Gillings

Nuclear Medicine and Biology, 2011

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ImmunoPET using engineered antibody fragments: fluorine-18 labeled diabodies for same-day imaging

Clifton Shen

Tumor Biology, 2012

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A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Inês Antunes

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Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: Synthesis and biological evaluation

Federica Pisaneschi

Bioorganic & Medicinal Chemistry, 2010

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Pyrazoles as Key Scaffolds for the Development of Fluorine-18-Labeled Radiotracers for Positron Emission Tomography (PET)

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A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

Jacob Hooker

2011

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A Dual Reporter Iodinated Labeling Reagent for Cancer Positron Emission Tomography Imaging and Fluorescence-Guided Surgery

John Maher

Journal of medicinal chemistry, 2018

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1-[3-(2-[ 18 F]Fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: Design, Synthesis, and Radiosynthesis of a New [ 18 F]Fluoropyridine-Based Maleimide Reagent for the Labeling of Peptides and Proteins

Raphaël Boisgard, Frédéric Dollé, Bertrand Tavitian

Bioconjugate Chemistry, 2005

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One-pot production of 18F-biotin by conjugation with 18F-FDG for pre-targeted imaging: Synthesis and radio-labelling of a PEGylated precursor

Tim Smith

Applied Radiation and Isotopes, 2011

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Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-γ ligands: potential positron emission tomography imaging agents

Carmen S Dence

2009

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Late stage 18F‐difluoromethyl labeling of N‐heteroaromatics with high molar activity for PET imaging

Joël Mercier

Angewandte Chemie

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[18F]ODIBO: a prosthetic group for bioorthogonal radiolabeling of macromolecules via strain-promoted alkyne–azide cycloaddition

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Organic and Biomolecular Chemistry, 2018

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One-step radiosynthesis of 4-nitrophenyl 2-[ 18 F]fluoropropionate ([ 18 F]NFP); improved preparation of radiolabeled peptides for PET imaging

Craig Hutton

Journal of Labelled Compounds and Radiopharmaceuticals, 2013

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Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents

Hermis Iatrou

Journal of the American Chemical Society, 2008

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The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule

Javad Garousi

Scientific Reports, 2017

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Synthesis and Binding Affinity of a Fluorine-Substituted Peroxisome Proliferator-Activated Gamma (PPARγ) Ligand as a Potential Positron Emission Tomography (PET) Imaging Agent

Robert Mach

Bioconjugate Chemistry, 2007

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Novel carbon-11 labeled 4-dimethylamino-but-2-enoic acid [4-(phenylamino)-quinazoline-6-yl]-amides: potential PET bioprobes for molecular imaging of EGFR-positive tumors

Yulia Rozen

Nuclear Medicine and Biology, 2004

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Preclinical Evaluation of [68Ga]Ga-DFO-ZEGFR:2377: A Promising Affibody-Based Probe for Noninvasive PET Imaging of EGFR Expression in Tumors

maryam oroujeni

Cells, 2018

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Late‐Stage 18 F‐Difluoromethyl Labeling of N‐Heteroaromatics with High Molar Activity for PET Imaging

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Angewandte Chemie, 2019

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Luminescent Difluoroboron β-Diketonate PEG-PLA Oxygen Nanosensors for Tumor Imaging

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Macromolecular Rapid Communications, 2015

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Using 5-deoxy-5-[18F]fluororibose to glycosylate peptides for positron emission tomography

Anne Roivainen

Nature Protocols, 2013

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Synthesis of 68Ga-Labeled Biopolymer-based Nanoparticle Imaging Agents for Positron-emission Tomography

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Anticancer Research, 2019

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Facile labelling of an anti-epidermal growth factor receptor Nanobody with 68Ga via a novel bifunctional desferal chelate for immuno-PET

Paul M. P. Bergen Henegouwen

European Journal of Nuclear Medicine and Molecular Imaging, 2011

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Formation of fluorine-18 labeled diaryl ureas—labeled VEGFR-2/PDGFR dual inhibitors as molecular imaging agents for angiogenesis

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Bioorganic & Medicinal Chemistry, 2008

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18F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry

Paul Kozlowski

Bioconjugate chemistry, 2015

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Pretargeted Positron Emission Tomography Imaging that Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry

Ziyue Jiang

ACS nano, 2016

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Cancer Imaging With Fluorine-18–Labeled Choline Derivatives

Marc Coel

Seminars in Nuclear Medicine, 2007

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