Evaluation of [11C]Me-NB1 as a potential PET radioligand for measuring GluN2B-containing NMDA receptors, drug occupancy and receptor crosstalk (original ) (raw )Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ1-Receptor–Targeted PET Imaging
Adrienne Herde
Journal of Nuclear Medicine, 2019
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Evaluation of the Novel PET Tracer [11C]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates
Jasper van der Aart
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Evaluation of 11C-NR2B-SMe and Its Enantiomers as PET Radioligands for Imaging the NR2B Subunit Within the NMDA Receptor Complex in Rats
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Journal of Nuclear Medicine, 2020
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Synthesis and in vitro evaluation of 18F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PET
Bengt Långström
Bioorganic & Medicinal Chemistry Letters, 2010
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In vivo evaluation of [ 11C]N-(2-chloro-5-thiomethylphenyl)-N′- (3-methoxy-phenyl)-N′-methylguanidine ([ 11C]GMOM) as a potential PET radiotracer for the PCP/NMDA receptor
abida sultana
Nuclear Medicine and Biology, 2004
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{"__content__"=>"Evaluation of the Novel PET Tracer [C]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates.", "sup"=>{"__content__"=>"11"}}
Jan Langermans
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2018
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Electrophysiological study, biodistribution in mice, and preliminary PET evaluation in a rhesus monkey of 1-amino-3-[18F]fluoromethyl-5-methyl- adamantane (18F-MEM): A potential radioligand for mapping the NMDA-receptor complex
Simon Ametamey , Samuel Samnick
1998
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Synthesis and preclinical evaluation of carbon-11 labelled N-((5-(4-fluoro-2-[(11)C]methoxyphenyl)pyridin-3-yl)methyl)cyclopentanamine as a PET tracer for NR2B subunit-containing NMDA receptors
Adriaan A Lammertsma
Nuclear medicine and biology, 2014
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Fluorine-18 Radiolabelling, Biodistribution Studies and Preliminary Pet Evaluation of a New Memantine Derivative for Imaging the NMDA Receptor
Simon Ametamey , Samuel Samnick
Journal of Receptors and Signal Transduction, 1999
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Jasper van der Aart
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Preclinical evaluation of [(18)F]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors
Josee Leysen
Nuclear medicine and biology, 2015
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MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit
Michela Fagiolini
PloS one, 2016
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Radiolabeling of [ 18 F]-fluoroethylnormemantine and initial in vivo evaluation of this innovative PET tracer for imaging the PCP sites of NMDA receptors
Hafid Belhadj-tahar , Anne-sophie Salabert
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A novel binding mode reveals two distinct classes of NMDA receptor GluN2B-selective antagonists
Derek Buhl
Molecular pharmacology, 2016
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Towards NR2B receptor selective imaging agents for PET—synthesis and evaluation of N-[11C]-(2-methoxy)benzyl (E)-styrene-, 2-naphthyl- and 4-trifluoromethoxyphenylamidine
Gjermund Henriksen
Bioorganic & Medicinal Chemistry, 2006
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Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity
Christian Madry
Frontiers in Pharmacology
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Development & Evaluation of Monoaminergic Agonist PET Tracers
Mikael Palner
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CP-101,606: An NR2B-Selective NMDA Receptor Antagonist
Ajit Shah , Frank Menniti , Keith Wilner
CNS Drug Reviews, 2006
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N′-3-(Trifluoromethyl)phenyl Derivatives of N-Aryl-N′-methylguanidines as Prospective PET Radioligands for the Open Channel of the N-Methyl-d-aspartate (NMDA) Receptor: Synthesis and Structure–Affinity Relationships
Robert Innis
Journal of Medicinal Chemistry, 2015
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Synthesis and evaluation in primates of (N-[11C]methyl)-benperidol as a pet tracer of cerebral D2 receptor binding
S. Moerlein
Journal of Labelled Compounds and Radiopharmaceuticals, 2001
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Evaluation of [methyl-3H]L655,708 and [ethyl-3H]RY80 as putative PET ligands for central GABAA receptors containing α5 subunit
Jolanta Opacka-Juffry
Nuclear Medicine and Biology, 1999
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N’ -3-(Trifluoromethyl)phenyl derivatives of N -aryl- N’ -methylguanidines as prospective PET radioligands for the open channel of the N -methyl-D-asparate (NMDA) receptor: synthesis and structure-affinity relationships
Lisheng Cai
Journal of Medicinal Chemistry, 2015
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[11C]Cyclopropyl-FLB 457: A PET radioligand for low densities of dopamine D2 receptors
Jogeshwar Mukherjee
Bioorganic & Medicinal Chemistry, 2008
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New N-aryl-N′-(3-(substituted)phenyl)-N′-methylguanidines as leads to potential PET radioligands for imaging the open NMDA receptor
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Bioorganic & Medicinal Chemistry Letters, 2015
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