Analysis of the human alpha-globin gene cluster in transgenic mice (original) (raw)
Analysis of a 70 kb segment of DNA containing the human ζ and α-globin genes linked to their regulatory element (HS-40) in transgenic mice
Dominic Wells
Nucleic Acids Research, 1994
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High-level erythroid expression of human alpha-globin genes in transgenic mice
Tim Townes
Proceedings of the National Academy of Sciences, 1989
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A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice
Tim Townes
Genes & Development, 1989
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Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes
Michael Antoniou
Genes & Development, 1993
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Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice
Tim Townes
Proceedings of the National Academy of Sciences, 1991
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Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells
Thalia Papayannopoulou
Proceedings of the National Academy of Sciences, 1995
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Position-independent, high-level expression of the human β-globin gene in transgenic mice
David Greaves
Cell, 1987
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Erythroid-specific expression of human beta-globin genes in transgenic mice
Tim Townes
The EMBO Journal, 1985
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High-level, erythroid-specific expression of the human alpha-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes
Miguel Vidal
Genes & Development, 1989
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Targeted inactivation of the major positive regulatory element (HS-40) of the human alpha-globin gene locus
D. Picketts
Blood, 1995
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Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice
Tim Townes
Proceedings of the National Academy of Sciences, 1987
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Multiple elements in human β-globin locus control region 5′ HS 2 are involved in enhancer activity and position independent, transgene expression
Dominic Ciavatta
Nucleic Acids Research, 1994
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Comparative analysis of the locus control region of the rabbit β-like globin gene cluster: HS3 increases transient expression of an embryonic ε-globin gene
Olga Selifonova
Nucleic Acids Research, 1993
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An embryonic-specific repressor element located 3′ to the Aγ-globin gene influences transcription of the human β-globin locus in transgenic mice
Eleni Katsantoni
Experimental Hematology, 2004
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Human gamma- to beta-globin gene switching in transgenic mice
Tim Townes
Genes & Development, 1990
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Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription
Mark Fear
Molecular and cellular biology, 1999
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Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expression
Dominic Ciavatta
Nucleic acids research, 1994
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Deletion of the mouse alpha -globin regulatory element (HS -26) has an unexpectedly mild phenotype
Jacqueline Sharpe
Blood, 2002
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Developmental regulation of human gamma- and beta-globin genes in the absence of the locus control region
Ajay Bhargava
Blood, 1994
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Hypersensitive Site 2 Specifies a Unique Function within the Human β-Globin Locus Control Region To Stimulate Globin Gene Transcription
Mark Fear
Molecular and Cellular Biology, 1999
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Correlation between patterns of DNase I-hypersensitive sites and upstream promoter activity of the human epsilon-globin gene at different stages of erythroid development
Pierre Bushel
Molecular and cellular biology, 1990
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Hypersensitive Site 2 Specifies a Unique Function within the Human b-Globin Locus Control Region To Stimulate Globin Gene Transcription
Mark Fear
1999
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Regulation of the Globin Genes
Paolo Moi
Pediatric Research, 2002
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High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells
W. Forrester
Proceedings of the National Academy of Sciences, 1990
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Full Activity From Human β-Globin Locus Control Region Transgenes Requires 5′HS1, Distal β-Globin Promoter, and 3′ β-Globin Sequences
Dylan Pannell
Blood, 1998
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Analysis of Mice Containing a Targeted Deletion of b-Globin Locus Control Region 59Hypersensitive Site 3
Elliot Epner
1996
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Expression of Human Globin Genes in Transgenic Mice Carrying the ?-Globin Gene Cluster with a Mutation Causing G ?? + Hereditary Persistence of Fetal Hemoglobin
Ajay Bhargava
Annals of the New York Academy of Sciences, 1990
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Coactivation of human α1- and α2-globin genes in single induced MEL cells containing one human α-globin locus
Francois Morle
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1997
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Derepression of human embryonic ζ-globin promoter by a locus-control region sequence
Bryan Huang
Proceedings of the National Academy of Sciences, 1998
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Tissue-specific histone modification and transcription factor binding in globin gene expression
Jacqueline Sharpe
Blood, 2007
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Conservation of position and sequence of a novel, widely expressed gene containing the major human α-globin regulatory element
D. Picketts
1995
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Expression of Human Globin Genes in Transgenic Mice Carrying the β‐Globin Gene Cluster with a Mutation Causing Gγβ+ Hereditary Persistence of Fetal Hemoglobina
Ajay Bhargava
Annals of the New York Academy of Sciences, 1990
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The "beta-like-globin" gene domain in human erythroid cells
Đào Văn Tuấn
Proceedings of the National Academy of Sciences, 1985
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Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region
W. Forrester, Elliot Epner
Genes & Development, 1992
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Promoters of the murine embryonic -like globin genes Ey and h1 do not compete for interaction with the -globin locus control region
Steven Fiering
Proceedings of the National Academy of Sciences, 2003
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