Asp49 phospholipase A 2–elaidoylamide complex: a new mode of inhibition (original) (raw)
Design of specific peptide inhibitors of phospholipase A 2 : structure of a complex formed between Russell's viper phospholipase A 2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS)
Jayasankar Jasti
Acta Crystallographica Section D Biological Crystallography, 2002
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Crystallographic portrayal of different conformational states of a Lys49 phospholipase A2 homologue: Insights into structural determinants for myotoxicity and dimeric configuration
Raghuvir Arni
International Journal of Biological Macromolecules, 2012
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Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms
Angelo Magro
Protein & Peptide Letters, 2009
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Crystallization and preliminary X-ray diffraction analysis of a Lys49-phospholipase A2 complexed with caffeic acid, a molecule with inhibitory properties against snake venoms
Marcos Fontes
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2011
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Crystal structure of the complex formed between a group I Phospholipase A2 and a naturally occurring fatty acid at 2.7 A resolution
TEJ SINGH
Protein Science, 2005
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Exploring the potent inhibitors and binding modes of phospholipase A2 through in silico investigation
Suvendu Ray
Journal of Biomolecular Structure and Dynamics, 2019
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Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A 2 class
Juliana dos Santos
Proteins: Structure, Function, and Bioinformatics, 2010
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Crystal structure of a novel myotoxic Arg49 phospholipase A2 homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus
Ulrich Kuch
Toxicon, 2008
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Crystal structure of a novel phospholipase A2 from crude venom of Indian cobra sub-species Naja naja sagittifera at 1.48 angstoms resolution
TEJ SINGH
Indian Journal of Biochemistry Biophysics, 2005
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Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)
Julián Fernández
Scientific Reports
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Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights
Marcos Fontes
Biochemical and Biophysical Research Communications, 2003
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The structure of the D49 phospholipase A2piratoxin III fromBothrops pirajaireveals unprecedented structural displacement of the calcium-binding loop: possible relationship to cooperative substrate binding
I. Polikarpov
Acta Crystallographica Section D Biological Crystallography, 2003
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Structure of N-Terminal Sequence Asp-Ala-Glu-Phe-Arg-His-Asp-Ser of Aβ-Peptide with Phospholipase A2 from Venom of Andaman Cobra Sub-Species Naja naja sagittifera at 2.0 Å Resolution
زينات مرزا سجاد كريم
International Journal of Molecular Sciences, 2014
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Crystallization and preliminary X-ray diffraction analysis of a novel Arg49 phospholipase A2homologue fromZhaoermia mangshanensisvenom
Ulrich Kuch
Acta crystallographica, 2007
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Structural and functional properties of BaTX, a new Lys49 phospholipase A 2 homologue isolated from the venom of the snake Bothrops alternatus
Bruno Lomonte
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Functions, structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A2 from Vipera nikolskii venom
Ru Bi
Toxicon, 2009
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In silico identification of viper phospholipaseA2 inhibitors: validation by in vitro, in vivo studies
mohd alam
Journal of Molecular Modeling
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Structural Elements of Ligand Recognition Site in Secretory Phospholipase A2 and Structure-Based Design of Specific Inhibitors
TEJ SINGH
Current Topics in Medicinal Chemistry, 2007
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Phospholipases A2 Protein Structure and Natural Products Interactions in Development of New Pharmaceuticals
Marcos Hikari Toyama
Protein Structure, 2012
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Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids
Marcos Fontes
PLOS ONE, 2015
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