SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes (original) (raw)

Anaerobic sulfatase-maturating enzyme - A mechanistic link with glycyl radical-activating enzymes

Sowmya Subramanian

Febs Journal, 2010

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Anaerobic sulfatase-maturating enzymes, first dual substrate radical S-adenosylmethionine enzymes

Hubert Vaudry

The Journal of biological chemistry, 2008

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S-Adenosylmethionine radical enzymes

Anjali Patwardhan

Bioorganic Chemistry, 2004

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Mechanistic Investigations of Anaerobic Sulfatase-Maturating Enzyme: Direct Cβ H-Atom Abstraction Catalyzed by a Radical AdoMet Enzyme

Hubert Vaudry

Journal of the American Chemical Society, 2009

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Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism

Catherine Drennan

Nature Chemical Biology, 2013

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Characterization of auxiliary iron-sulfur clusters in a radicalS-adenosylmethionine enzyme PqqE fromMethylobacterium extorquensAM1

Natsaran Saichana

FEBS Open Bio, 2017

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Structural diversity in the AdoMet radical enzyme superfamily

Anna Croft

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Radical S-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

Angad Mehta

Journal of Biological Chemistry, 2014

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At the confluence of ribosomally synthesized peptide modification and radical S-adenosylmethionine (SAM) enzymology

Judith Klinman

Journal of Biological Chemistry, 2017

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The generation of 5′-deoxyadenosyl radicals by adenosylmethionine-dependent radical enzymes

J. Jarrett

Current Opinion in Chemical Biology, 2003

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Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme

Boris Dzikovski

Journal of the American Chemical Society, 2016

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Mechanistic Studies of Radical SAM Enzymes: Pyruvate Formate-Lyase Activating Enzyme and Lysine 2,3-Aminomutase Case Studies

Stella Impano

Methods in Enzymology, 2018

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The Radical S-Adenosyl-L-methionine Enzyme QhpD Catalyzes Sequential Formation of Intra-protein Sulfur-to-Methylene Carbon Thioether Bonds

Motonari Tsubaki

The Journal of biological chemistry, 2015

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Anaerobic Sulfatase-Maturating Enzymes: Radical SAM Enzymes Able To Catalyze in Vitro Sulfatase Post-translational Modification

Hubert Vaudry

Journal of the American Chemical Society, 2007

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Radical SAM enzymes in methylation and methylthiolation

Rachel Hutcheson

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Radical SAM Enzymes and Metallocofactor Assembly: A Structural Point of View

Yvain Nicolet

ACS Bio & Med Chem Au, 2021

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Substrate-Dependent Cleavage Site Selection by Unconventional Radical SAM Enzymes in Diphthamide Biosynthesis

Boris Dzikovski

Journal of the American Chemical Society, 2017

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Carbon–sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE

Yvain Nicolet

Nature Chemistry, 2016

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Structure and Catalytic Mechanism of Radical SAM Methylases

Yvain Nicolet

Life

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Resolving the Multidecade-Long Mystery in MoaA Radical SAM Enzyme Reveals New Opportunities to Tackle Human Health Problems

Kenichi Yokoyama

ACS Bio & Med Chem Au

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Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

Jorge Spíndola

Nucleic Acids Research, 2001

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Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes

Jürgen Moser

The EMBO Journal, 2003

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How a Subfamily of Radical S-Adenosylmethionine Enzymes Became a Mainstay of Ribosomally Synthesized and Post-translationally Modified Peptide Discovery

Aigera Mendauletova

ACS Bio & Med Chem Au

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Physical and Functional Interactions of a Monothiol Glutaredoxin and an Iron Sulfur Cluster Carrier Protein with the Sulfur-donating Radical S-Adenosyl-L-methionine Enzyme MiaB

Edward Baidoo

Journal of Biological Chemistry, 2013

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4-Demethylwyosine Synthase from Pyrococcus abyssi Is a Radical-S-adenosyl-l-methionine Enzyme with an Additional [4Fe-4S]+2 Cluster That Interacts with the Pyruvate Co-substrate

Velavan Kathirvelu

Journal of Biological Chemistry, 2012

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X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE

Judith Klinman

Biochemistry, 2018

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The Radical SAM Superfamily

Adrian Hegeman

Critical Reviews in Biochemistry and Molecular Biology, 2008

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Lessons From the Studies of a CC Bond Forming Radical SAM Enzyme in Molybdenum Cofactor Biosynthesis

Kenichi Yokoyama

Methods in enzymology, 2018

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X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

Catherine Drennan

Proceedings of the National Academy of Sciences, 2013

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Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme

Rachel Hutcheson

Journal of the American Chemical Society, 2017

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S-Adenosyl-l-methionine Enzyme MiaB Sulfur-donating Radical Cluster Carrier Protein with the Sulfur Monothiol Glutaredoxin and an Iron Physical and Functional Interactions of a

Jay D Keasling

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Structural Insights into Radical Generation by the Radical SAM Superfamily

Catherine Drennan

Chemical Reviews, 2011

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Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme

F. Berkovitch, J. Jarrett, Yvain Nicolet, Catherine Drennan

Science, 2004

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On the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes

Simon Arragain

Frontiers in Chemistry, 2017

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S K-edge XAS and DFT Calculations on SAM Dependent Pyruvate Formate-Lyase Activating Enzyme: Nature of Interaction between the Fe 4 S 4 Cluster and SAM and its Role in Reactivity

Abhishek Dey

Journal of the American Chemical Society, 2011

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